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Mattias Landfors
Contact
E-mail
mattias.landfors@umu.se
Phone
+46 90 785 44 10
Works at
Affiliation
Staff scientist at
Department of Medical Biosciences
Location
By 6M, Sjukhusområdet
Umeå universitet, 901 85 Umeå
Publications
Publications
Research
Research
2024
Semimethylation is a feature of diffuse large B-cell lymphoma, and subgroups with poor prognosis are characterized by global hypomethylation and short telomere length
Clinical Epigenetics
, BioMed Central (BMC) 2024, Vol. 16, (1)
Carlund, Olivia; Thörn, Elina; Osterman, Pia; et al.
2023
DNA methylation variations and epigenetic aging in telomere biology disorders
Scientific Reports
, Springer Nature 2023, Vol. 13, (1)
Carlund, Olivia; Norberg, Anna; Osterman, Pia; et al.
2023
Pre-clinical evaluation of the hypomethylating agent decitabine for the treatment of t-cell lymphoblastic lymphoma
Cancers
, MDPI 2023, Vol. 15, (3)
Provez, Lien; Putteman, Tom; Landfors, Mattias; et al.
2023
Sixteen-year longitudinal evaluation of blood-based DNA methylation biomarkers for early prediction of Alzheimer’s disease
Journal of Alzheimer's Disease
, IOS Press 2023, Vol. 94, (4) : 1443-1464
Schäfer Hackenhaar, Fernanda; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
2023
DNA methylation changes and increased mRNA expression of coagulation proteins, factor V and thrombomodulin in Fuchs endothelial corneal dystrophy
Cellular and Molecular Life Sciences (CMLS)
, Springer 2023, Vol. 80, (3)
Westin, Ida Maria; Landfors, Mattias; Giannopoulos, Antonios; et al.
2021
A novel DNA methylation signature is associated with androgen receptor activity and patient prognosis in bone metastatic prostate cancer
Clinical Epigenetics
, BioMed Central 2021, Vol. 13, (1)
Bovinder Ylitalo, Erik; Thysell, Elin; Landfors, Mattias; et al.
2021
Short leukocyte telomeres, but not telomere attrition rates, predict memory decline in the 20-year longitudinal Betula study
The journals of gerontology. Series A, Biological sciences and medical sciences
, Oxford University Press 2021, Vol. 76, (6) : 955-963
Pudas, Sara; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
2021
Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-
APOE
ε4-carriers
Alzheimer's Research & Therapy
, BioMed Central (BMC) 2021, Vol. 13
Schäfer Hackenhaar, Fernanda; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
2020
Combining epigenetic and clinicopathological variables improves specificity in prognostic prediction in clear cell renal cell carcinoma
Journal of Translational Medicine
, Vol. 18, (1)
Andersson-Evelönn, Emma; Vidman, Linda; Källberg, David; et al.
2020
DNA methylation and copy number variation profiling of T-cell lymphoblastic leukemia and lymphoma
Blood Cancer Journal
, Nature Publishing Group 2020, Vol. 10, (4)
Haider, Zahra; Landfors, Mattias; Golovleva, Irina; et al.
2020
Hematopoietic cellular aging is not accelerated during the first 2 years of life in children born preterm
Pediatric Research
, Nature Publishing Group 2020, Vol. 88
Henckel, Ewa; Landfors, Mattias; Haider, Zahra; et al.
2020
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia
Blood cancer discovery
, American Association for Cancer Research 2020, Vol. 1, (3) : 274-289
Roels, Juliette; Thénoz, Morgan; Szarzyńska, Bronisława; et al.
2019
DNA methylation associates with survival in non-metastatic clear cell renal cell carcinoma
BMC Cancer
, BioMed Central 2019, Vol. 19
Andersson Evelönn, Emma; Landfors, Mattias; Haider, Zahra; et al.
2019
An integrated transcriptome analysis in T-cell acute lymphoblastic leukemia links DNA methylation subgroups to dysregulated TAL1 and ANTP homeobox gene expression
Cancer Medicine
, John Wiley & Sons 2019, Vol. 8, (1) : 311-324
Haider, Zahra; Larsson, Pär; Landfors, Mattias; et al.
2018
DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia
Clinical Epigenetics
, BioMed Central 2018, Vol. 10
Borssén, Magnus; Nordlund, Jessica; Haider, Zahra; et al.
2017
Maintained memory in aging is associated with young epigenetic age
Neurobiology of Aging
, Elsevier 2017, Vol. 55 : 167-171
Degerman, Sofie; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
2017
Decreased telomere length in children with cartilage-hair hypoplasia
Journal of Medical Genetics
, BMJ PUBLISHING GROUP 2017, Vol. 54, (5) : 365-370
Kostjukovits, Svetlana; Degerman, Sofie; Pekkinen, Minna; et al.
2016
DNA methylation status defines clinicopathological parameters including survival for patients with clear cell renal cell carcinoma (ccRCC)
Tumor Biology
, Vol. 37, (8) : 10219-10228
Andersson Evelönn, Emma; Degerman, Sofie; Köhn, Linda; et al.
2016
DNA Methylation Adds Prognostic Value to Minimal Residual Disease Status in Pediatric T-Cell Acute Lymphoblastic Leukemia
Pediatric Blood & Cancer
, Vol. 63, (7) : 1185-1192
Borssén, Magnus; Haider, Zahra; Landfors, Mattias; et al.
2014
Long Leukocyte Telomere Length at Diagnosis Is a Risk Factor for Dementia Progression in Idiopathic Parkinsonism
PLOS ONE
, Vol. 9, (12)
Degerman, Sofie; Domellöf, Magdalena; Landfors, Mattias; et al.
2014
Immortalization of T-Cells Is Accompanied by Gradual Changes in CpG Methylation Resulting in a Profile Resembling a Subset of T-Cell Leukemias
Neoplasia
, Vol. 16, (7) : 606-615
Degerman, Sofie; Landfors, Mattias; Siwicki, Jan Konrad; et al.
2012
Pr is a member of a restricted class of σ70-dependent promoters that lack a recognizable -10 element
Nucleic Acids Research
, Vol. 40, (22) : 11308-11320
Del Peso-Santos, Teresa; Landfors, Mattias; Skärfstad, Eleonore; et al.
2012
Normalization and analysis of high-dimensional genomics data
Umeå: Umeå Universitet 2012
Landfors, Mattias
2011
Normalization of high dimensional genomics data where the distribution of the altered variables is skewed
PLOS ONE
, Vol. 6, (11) : e27942-
Landfors, Mattias; Philip, Philge; Rydén, Patrik; et al.
2011
Classification of microarrays: synergistic effects between normalization, gene selection and machine learning
BMC Bioinformatics
, BioMed Central 2011, Vol. 12, (1)
Önskog, Jenny; Freyhult, Eva; Landfors, Mattias; et al.
2010
Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
BMC Bioinformatics
, BioMed Central 2010, Vol. 11
Freyhult, Eva; Landfors, Mattias; Önskog, Jenny; et al.
2009
Bioinformatics strategies for cDNA-microarray data processing
Batch effects and noise in microarray experiments: sources and solutions
, Wiley and Sons 2009 : 61-74
Fahlén, Jessica; Landfors, Mattias; Freyhult, Eva; et al.
2009
MC-normalization: a novel method for dye-normalization of two-channel microarray data
Statistical Applications in Genetics and Molecular Biology
, Berkeley: The Berkeley Electronic Press (bepress) 2009, Vol. 8, (1) : 42-
Landfors, Mattias; Fahlén, Jessica; Rydén, Patrik
2006
Evaluation of microarray data normalization procedures using spike-in experiments
BMC Bioinformatics
, London: BioMed Central Ltd 2006, Vol. 7, (300) : 17-
Rydén, Patrik; Andersson, Henrik; Landfors, Mattias; et al.
Combining epigenetic and clinicopathological variables improves prognostic prediction in clear cell Renal Cell Carcinoma
Andersson-Evelönn, Emma; Vidman, Linda; Källberg, David; et al.
Integrated DNA methylation and gene expression analysis of molecular heterogeneity in prostate cancer bone metastasis
Bovinder Ylitalo, Erik; Thysell, Elin; Landfors, Mattias; et al.
Epigenetic and genetic distinctions between T-cell acute lymphoblastic leukemia and lymphoma
Haider, Zahra; Landfors, Mattias; Golovleva, Irina; et al.
Prognostic Significance of Hypermethylation in the Promoter Region of the Wilms’ Tumour Gene 1 in Clear Cell Renal Cell Carcinoma
Li, Xingru; Andersson-Evelönn, Emma; Wang, Sihan; et al.
View publications in DiVA
Research groups
Group member
Sofie Degerman Lab
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