Mattias Landfors

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Staff scientist at Department of Medical Biosciences

By 6M, Sjukhusområdet Umeå universitet, 901 85 Umeå

Semimethylation is a feature of diffuse large B-cell lymphoma, and subgroups with poor prognosis are characterized by global hypomethylation and short telomere length

Clinical Epigenetics, BioMed Central (BMC) 2024, Vol. 16, (1)

Carlund, Olivia; Thörn, Elina; Osterman, Pia; et al.

DNA methylation variations and epigenetic aging in telomere biology disorders

Scientific Reports, Springer Nature 2023, Vol. 13, (1)

Carlund, Olivia; Norberg, Anna; Osterman, Pia; et al.

Pre-clinical evaluation of the hypomethylating agent decitabine for the treatment of t-cell lymphoblastic lymphoma

Cancers, MDPI 2023, Vol. 15, (3)

Provez, Lien; Putteman, Tom; Landfors, Mattias; et al.

Sixteen-year longitudinal evaluation of blood-based DNA methylation biomarkers for early prediction of Alzheimer’s disease

Journal of Alzheimer's Disease, IOS Press 2023, Vol. 94, (4) : 1443-1464

Schäfer Hackenhaar, Fernanda; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.

DNA methylation changes and increased mRNA expression of coagulation proteins, factor V and thrombomodulin in Fuchs endothelial corneal dystrophy

Cellular and Molecular Life Sciences (CMLS), Springer 2023, Vol. 80, (3)

Westin, Ida Maria; Landfors, Mattias; Giannopoulos, Antonios; et al.

A novel DNA methylation signature is associated with androgen receptor activity and patient prognosis in bone metastatic prostate cancer

Clinical Epigenetics, BioMed Central 2021, Vol. 13, (1)

Bovinder Ylitalo, Erik; Thysell, Elin; Landfors, Mattias; et al.

Short leukocyte telomeres, but not telomere attrition rates, predict memory decline in the 20-year longitudinal Betula study

The journals of gerontology. Series A, Biological sciences and medical sciences, Oxford University Press 2021, Vol. 76, (6) : 955-963

Pudas, Sara; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.

Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-APOE ε4-carriers

Alzheimer's Research & Therapy, BioMed Central (BMC) 2021, Vol. 13

Schäfer Hackenhaar, Fernanda; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.

Combining epigenetic and clinicopathological variables improves specificity in prognostic prediction in clear cell renal cell carcinoma

Journal of Translational Medicine, Vol. 18, (1)

Andersson-Evelönn, Emma; Vidman, Linda; Källberg, David; et al.

DNA methylation and copy number variation profiling of T-cell lymphoblastic leukemia and lymphoma

Blood Cancer Journal, Nature Publishing Group 2020, Vol. 10, (4)

Haider, Zahra; Landfors, Mattias; Golovleva, Irina; et al.

Hematopoietic cellular aging is not accelerated during the first 2 years of life in children born preterm

Pediatric Research, Nature Publishing Group 2020, Vol. 88

Henckel, Ewa; Landfors, Mattias; Haider, Zahra; et al.

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

Blood cancer discovery, American Association for Cancer Research 2020, Vol. 1, (3) : 274-289

Roels, Juliette; Thénoz, Morgan; Szarzyńska, Bronisława; et al.

DNA methylation associates with survival in non-metastatic clear cell renal cell carcinoma

BMC Cancer, BioMed Central 2019, Vol. 19

Andersson Evelönn, Emma; Landfors, Mattias; Haider, Zahra; et al.

An integrated transcriptome analysis in T-cell acute lymphoblastic leukemia links DNA methylation subgroups to dysregulated TAL1 and ANTP homeobox gene expression

Cancer Medicine, John Wiley & Sons 2019, Vol. 8, (1) : 311-324

Haider, Zahra; Larsson, Pär; Landfors, Mattias; et al.

DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia

Clinical Epigenetics, BioMed Central 2018, Vol. 10

Borssén, Magnus; Nordlund, Jessica; Haider, Zahra; et al.

Maintained memory in aging is associated with young epigenetic age

Neurobiology of Aging, Elsevier 2017, Vol. 55 : 167-171

Degerman, Sofie; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.

Decreased telomere length in children with cartilage-hair hypoplasia

Journal of Medical Genetics, BMJ PUBLISHING GROUP 2017, Vol. 54, (5) : 365-370

Kostjukovits, Svetlana; Degerman, Sofie; Pekkinen, Minna; et al.

DNA methylation status defines clinicopathological parameters including survival for patients with clear cell renal cell carcinoma (ccRCC)

Tumor Biology, Vol. 37, (8) : 10219-10228

Andersson Evelönn, Emma; Degerman, Sofie; Köhn, Linda; et al.

DNA Methylation Adds Prognostic Value to Minimal Residual Disease Status in Pediatric T-Cell Acute Lymphoblastic Leukemia

Pediatric Blood & Cancer, Vol. 63, (7) : 1185-1192

Borssén, Magnus; Haider, Zahra; Landfors, Mattias; et al.

Long Leukocyte Telomere Length at Diagnosis Is a Risk Factor for Dementia Progression in Idiopathic Parkinsonism

PLOS ONE, Vol. 9, (12)

Degerman, Sofie; Domellöf, Magdalena; Landfors, Mattias; et al.

Immortalization of T-Cells Is Accompanied by Gradual Changes in CpG Methylation Resulting in a Profile Resembling a Subset of T-Cell Leukemias

Neoplasia, Vol. 16, (7) : 606-615

Degerman, Sofie; Landfors, Mattias; Siwicki, Jan Konrad; et al.

Pr is a member of a restricted class of σ70-dependent promoters that lack a recognizable -10 element

Nucleic Acids Research, Vol. 40, (22) : 11308-11320

Del Peso-Santos, Teresa; Landfors, Mattias; Skärfstad, Eleonore; et al.

Normalization and analysis of high-dimensional genomics data

Umeå: Umeå Universitet 2012

Landfors, Mattias

Normalization of high dimensional genomics data where the distribution of the altered variables is skewed

PLOS ONE, Vol. 6, (11) : e27942-

Landfors, Mattias; Philip, Philge; Rydén, Patrik; et al.

Classification of microarrays: synergistic effects between normalization, gene selection and machine learning

BMC Bioinformatics, BioMed Central 2011, Vol. 12, (1)

Önskog, Jenny; Freyhult, Eva; Landfors, Mattias; et al.

Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering

BMC Bioinformatics, BioMed Central 2010, Vol. 11

Freyhult, Eva; Landfors, Mattias; Önskog, Jenny; et al.

Bioinformatics strategies for cDNA-microarray data processing

Batch effects and noise in microarray experiments: sources and solutions, Wiley and Sons 2009 : 61-74

Fahlén, Jessica; Landfors, Mattias; Freyhult, Eva; et al.

MC-normalization: a novel method for dye-normalization of two-channel microarray data

Statistical Applications in Genetics and Molecular Biology, Berkeley: The Berkeley Electronic Press (bepress) 2009, Vol. 8, (1) : 42-

Landfors, Mattias; Fahlén, Jessica; Rydén, Patrik

Evaluation of microarray data normalization procedures using spike-in experiments

BMC Bioinformatics, London: BioMed Central Ltd 2006, Vol. 7, (300) : 17-

Rydén, Patrik; Andersson, Henrik; Landfors, Mattias; et al.

Combining epigenetic and clinicopathological variables improves prognostic prediction in clear cell Renal Cell Carcinoma

Andersson-Evelönn, Emma; Vidman, Linda; Källberg, David; et al.

Integrated DNA methylation and gene expression analysis of molecular heterogeneity in prostate cancer bone metastasis

Bovinder Ylitalo, Erik; Thysell, Elin; Landfors, Mattias; et al.

Epigenetic and genetic distinctions between T-cell acute lymphoblastic leukemia and lymphoma

Haider, Zahra; Landfors, Mattias; Golovleva, Irina; et al.

Prognostic Significance of Hypermethylation in the Promoter Region of the Wilms’ Tumour Gene 1 in Clear Cell Renal Cell Carcinoma

Li, Xingru; Andersson-Evelönn, Emma; Wang, Sihan; et al.

View publications in DiVA

Research groups

Group member

Sofie Degerman Lab