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Simon Tuck
Vetenskaplig meritering:
Docent
Kontakt
E-post
simon.tuck@umu.se
Telefon
090-786 67 87
Verksam vid
Anknytning
Professor vid
Institutionen för medicinsk och translationell biologi
Enhet: Avdelningen för molekylär medicin
Plats
hus H, Johan Bures väg 12, Biologihuset
Umeå universitet, 901 87 Umeå
Presentation
Presentation
Publikationer
Publikationer
Forskning
Forskning
Hemsida
2021
LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes
Communications Biology
, Springer Nature 2021, Vol. 4, (1)
Herdenberg, Carl; Mutie, Pascal; Billing, Ola; et al.
2021
C. elegans TAT-6, a putative aminophospholipid translocase, is expressed in sujc cells in the hermaphrodite gonad
microPublication biology
Nilsson, Lars; Rahmani, Shapour; Tuck, Simon
2021
EGL-4 promotes turning behavior of C. elegans males during mating
microPublication biology
Rahmani, Shapour; Tuck, Simon
2019
Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems
Molecular Nutrition & Food Research
, WILEY 2019, Vol. 63, (9)
Rohn, Isabelle; Raschke, Stefanie; Aschner, Michael; et al.
2018
Flagella-mediated secretion of a novel
Vibrio cholerae
cytotoxin affecting both vertebrate and invertebrate hosts
Communications Biology
, Springer Nature Publishing AG 2018, Vol. 1
Dongre, Mitesh; Singh, Bhupender; Aung, Kyaw Min; et al.
2018
Selenium species-dependent toxicity, bioavailability and metabolic transformations in
Caenorhabditis elegans
Metallomics
, Royal Society of Chemistry 2018, Vol. 10, (6) : 818-827
Rohn, Isabelle; Marschall, Talke Anu; Kroepfl, Nina; et al.
2017
Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses
PLOS Genetics
, Vol. 13, (7)
Navarro-Gonzalez, Carmen; Moukadiri, Ismail; Villarroya, Magda; et al.
2016
Fourier transform infrared microspectroscopy for the analysis of the biochemical composition of
C. elegans
worms
Worm
, Taylor & Francis 2016, Vol. 5, (1)
Sheng, Ming; Gorzsás, András; Tuck, Simon
2015
Aberrant Fat Metabolism in Caenorhabditis elegans Mutants with Defects in the Defecation Motor Program
PLOS ONE
, PLOS one 2015, Vol. 10, (4)
Sheng, Ming; Hosseinzadeh, Ava; Muralidharan, Somsundar Veppil; et al.
2014
The control of cell growth and body size in Caenorhabditis elegans
Experimental Cell Research
, Vol. 321, (1) : 71-76
Tuck, Simon
2012
S6K links cell fate, cell cycle and nutrient response in C. elegans germline stem/progenitor cells.
Development
, Vol. 139, (5) : 859-870
Korta, Dorota Z; Tuck, Simon; Hubbard, E Jane Albert
2011
Tissue- and paralogue-specific functions of acyl-CoA-binding proteins in lipid metabolism in Caenorhabditis elegans
Biochemical Journal
, Vol. 437, (2) : 231-241
Elle, Ida C; Simonsen, Karina T; Olsen, Louise C B; et al.
2011
Caenorhabditis elegans Numb Inhibits Endocytic Recycling by Binding TAT-1 Aminophospholipid Translocase
Traffic: the International Journal of Intracellular Transport
, Malden: Wiley-Blackwell 2011, Vol. 12, (12) : 1839-1849
Nilsson, Lars; Jonsson, Eva; Tuck, Simon
2011
Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 108, (3) : 1064-1069
Stenvall, Jörgen; Fierro-González, Juan Carlos; Swoboda, Peter; et al.
2011
Extracellular vesicles: budding regulated by a phosphatidylethanolamine translocase
Current Biology
, Vol. 21, (24) : R988-R990
Tuck, Simon
2010
TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans
Molecular Biology of the Cell
, American Society for Cell Biology 2010, Vol. 21, (13) : 2285-2296
Chotard, Laëtitia; Mishra, Ashwini K; Sylvain, Marc-André; et al.
2009
Defects in tRNA modification associated with neurological and developmental dysfunctions in Caenorhabditis elegans elongator mutants
PLoS genetics
, Vol. 5, (7) : e1000561-
Chen, Changchun; Tuck, Simon; Byström, Anders S
2009
The C. elegans P4-ATPase TAT-1 regulates Lysosome Biogenesis and Endocytosis
Traffic: the International Journal of Intracellular Transport
, Vol. 10, (1) : 88-100
Ruaud, Anne-Françoise; Nilsson, Lars; Richard, Fabrice; et al.
2008
Caenorhabditis elegans num-1 negatively regulates endocytic recycling
Genetics
, Vol. 179 : 375-387
Nilsson, Lars; Conradt, Barbara; Ruaud, Anne-Françoise; et al.
2007
Diet-dependent depletion of queuosine in tRNAs in Caenorhabditis elegans does not lead to a developmental block.
J Biosci
, Vol. 32, (4) : 747-54
Gaur, Rahul; Björk, Glenn; Tuck, Simon; et al.
2007
ASNA-1 positively regulates insulin secretion in C. elegans and mammalian cells.
Cell
, Vol. 128, (3) : 577-87
Kao, Gautam; Nordenson, Cecilia; Still, Maria; et al.
2006
MAA-1, a novel acyl-CoA-binding protein involved in endosomal vesicle transport in Caenorhabditis elegans.
Mol Biol Cell
, Vol. 17, (10) : 4318-29
Larsen, Morten K; Tuck, Simon; Faergeman, Nils J; et al.
2006
A
Vibrio cholerae
protease needed for killing of
Caenorhabditis elegans
has a role in protection from natural predator grazing
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 103, (24) : 9280-9285
Vaitkevicius, Karolis; Lindmark, Barbro; Ou, Gangwei; et al.
2005
A Caenorhabditis elegans mutant lacking functional nicotinamide nucleotide transhydrogenase displays increased sensitivity to oxidative stress.
Free Radic Biol Med
, Vol. 38, (11) : 1518-25
Arkblad, Eva L; Tuck, Simon; Pestov, Nikolay B; et al.
2005
Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling.
Proc Natl Acad Sci U S A
, Vol. 102, (33) : 11757-62
Rocheleau, Christian E; Rönnlund, Agneta; Tuck, Simon; et al.
2005
C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage.
Cell Death Differ
, Vol. 12, (2) : 153-61
Schumacher, B; Schertel, C; Wittenburg, N; et al.
2005
lin-1 has both positive and negative functions in specifying multiple cell fates induced by Ras/MAP kinase signaling in C. elegans.
Dev Biol
, Vol. 286, (1) : 338-51
Tiensuu, Teresa; Larsen, Morten Krog; Vernersson, Emma; et al.
2004
C. elegans SUR-6/PR55 cooperates with LET-92/protein phosphatase 2A and promotes Raf activity independently of inhibitory Akt phosphorylation sites
Development
, Cambridge: Company of Biologists Limited 2004, Vol. 131, (4) : 755-765
Kao, Gautam; Tuck, Simon; Baillie, David; et al.
2002
Stress response in
Caenorhabditis elegans
caused by optical tweezers: wavelength, power, and time dependence
Biophysical Journal
, Biophysical Society 2002, Vol. 82, (4) : 2224-2231
Leitz, Guenther; Fällman, Erik; Tuck, Simon; et al.
2002
Increased or decreased levels of Caenorhabditis elegans lon-3, a gene encoding a collagen, cause reciprocal changes in body length.
Genetics
, Vol. 161, (1) : 83-97
Nyström, Josefin; Shen, Zai-Zhong; Aili, Margareta; et al.
2000
EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans.
Mol Biol Cell
, Vol. 11, (4) : 1401-19
Furuta, T; Tuck, S; Kirchner, J; et al.
2000
Caenorhabditis elegans lin-25: a study of its role in multiple cell fate specification events involving Ras and the identification and characterization of evolutionarily conserved domains.
Genetics
, Vol. 156, (3) : 1083-96
Nilsson, L; Tiensuu, T; Tuck, S
1999
A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting.
Development
, Vol. 126, (3) : 597-606
Yochem, J; Tuck, S; Greenwald, I; et al.
1998
Caenorhabditis elegans lin-25: cellular focus, protein expression and requirement for sur-2 during induction of vulval fates.
Development
, Vol. 125, (23) : 4809-19
Nilsson, L; Li, X; Tiensuu, T; et al.
TAT-5 and TAT-6 P4-family ATPases regulate the release of extracellular vesicles containing polycystins from Caenorhabditis elegans sensilla
Nilsson, Lars; Rahmani, Shapour; Hubert, Madlen; et al.
Increased release of extracellular vesicles from C. elegans sensilla in mutants with lysosomal defects
Rahmani, Shapour; Tuck, Simon
Activation of cGMP signalling inhibits response behaviour of C. elegans males during mating
Rahmani, Shapour; Tuck, Simon
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