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English
Simon Tuck
Vetenskaplig meritering:
Docent
Kontakt
E-post
simon.tuck@umu.se
Telefon
090-786 67 87
Verksam vid
Anknytning
Professor vid
Institutionen för medicinsk och translationell biologi
Enhet: Avdelningen för molekylär medicin
Plats
hus H, Johan Bures väg 12, Biologihuset
Umeå universitet, 901 87 Umeå
Presentation
Presentation
Publikationer
Publikationer
Forskning
Forskning
Hemsida
2025
Shaker/Kv1 potassium channel SHK-1 protects against pathogen infection and oxidative stress in C. elegans
PLOS Genetics
, Public Library of Science (PLoS) 2025, Vol. 21, (2)
Pu, Longjun; Wang, Jing; Nilsson, Lars; et al.
2021
LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes
Communications Biology
, Springer Nature 2021, Vol. 4, (1)
Herdenberg, Carl; Mutie, Pascal; Billing, Ola; et al.
2021
C. elegans TAT-6, a putative aminophospholipid translocase, is expressed in sujc cells in the hermaphrodite gonad
microPublication biology
Nilsson, Lars; Rahmani, Shapour; Tuck, Simon
2021
EGL-4 promotes turning behavior of C. elegans males during mating
microPublication biology
Rahmani, Shapour; Tuck, Simon
2019
Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems
Molecular Nutrition & Food Research
, WILEY 2019, Vol. 63, (9)
Rohn, Isabelle; Raschke, Stefanie; Aschner, Michael; et al.
2018
Flagella-mediated secretion of a novel
Vibrio cholerae
cytotoxin affecting both vertebrate and invertebrate hosts
Communications Biology
, Springer Nature Publishing AG 2018, Vol. 1
Dongre, Mitesh; Singh, Bhupender; Aung, Kyaw Min; et al.
2018
Selenium species-dependent toxicity, bioavailability and metabolic transformations in
Caenorhabditis elegans
Metallomics
, Royal Society of Chemistry 2018, Vol. 10, (6) : 818-827
Rohn, Isabelle; Marschall, Talke Anu; Kroepfl, Nina; et al.
2017
Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses
PLOS Genetics
, Vol. 13, (7)
Navarro-Gonzalez, Carmen; Moukadiri, Ismail; Villarroya, Magda; et al.
2016
Fourier transform infrared microspectroscopy for the analysis of the biochemical composition of
C. elegans
worms
Worm
, Taylor & Francis 2016, Vol. 5, (1)
Sheng, Ming; Gorzsás, András; Tuck, Simon
2015
Aberrant Fat Metabolism in Caenorhabditis elegans Mutants with Defects in the Defecation Motor Program
PLOS ONE
, PLOS one 2015, Vol. 10, (4)
Sheng, Ming; Hosseinzadeh, Ava; Muralidharan, Somsundar Veppil; et al.
2014
The control of cell growth and body size in Caenorhabditis elegans
Experimental Cell Research
, Vol. 321, (1) : 71-76
Tuck, Simon
2012
S6K links cell fate, cell cycle and nutrient response in C. elegans germline stem/progenitor cells.
Development
, Vol. 139, (5) : 859-870
Korta, Dorota Z; Tuck, Simon; Hubbard, E Jane Albert
2011
Tissue- and paralogue-specific functions of acyl-CoA-binding proteins in lipid metabolism in Caenorhabditis elegans
Biochemical Journal
, Vol. 437, (2) : 231-241
Elle, Ida C; Simonsen, Karina T; Olsen, Louise C B; et al.
2011
Caenorhabditis elegans Numb Inhibits Endocytic Recycling by Binding TAT-1 Aminophospholipid Translocase
Traffic: the International Journal of Intracellular Transport
, Malden: Wiley-Blackwell 2011, Vol. 12, (12) : 1839-1849
Nilsson, Lars; Jonsson, Eva; Tuck, Simon
2011
Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 108, (3) : 1064-1069
Stenvall, Jörgen; Fierro-González, Juan Carlos; Swoboda, Peter; et al.
2011
Extracellular vesicles: budding regulated by a phosphatidylethanolamine translocase
Current Biology
, Vol. 21, (24) : R988-R990
Tuck, Simon
2010
TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans
Molecular Biology of the Cell
, American Society for Cell Biology 2010, Vol. 21, (13) : 2285-2296
Chotard, Laëtitia; Mishra, Ashwini K; Sylvain, Marc-André; et al.
2009
Defects in tRNA modification associated with neurological and developmental dysfunctions in Caenorhabditis elegans elongator mutants
PLoS genetics
, Vol. 5, (7) : e1000561-
Chen, Changchun; Tuck, Simon; Byström, Anders S
2009
The C. elegans P4-ATPase TAT-1 regulates Lysosome Biogenesis and Endocytosis
Traffic: the International Journal of Intracellular Transport
, Vol. 10, (1) : 88-100
Ruaud, Anne-Françoise; Nilsson, Lars; Richard, Fabrice; et al.
2008
Caenorhabditis elegans num-1 negatively regulates endocytic recycling
Genetics
, Vol. 179 : 375-387
Nilsson, Lars; Conradt, Barbara; Ruaud, Anne-Françoise; et al.
2007
Diet-dependent depletion of queuosine in tRNAs in Caenorhabditis elegans does not lead to a developmental block.
J Biosci
, Vol. 32, (4) : 747-54
Gaur, Rahul; Björk, Glenn; Tuck, Simon; et al.
2007
ASNA-1 positively regulates insulin secretion in C. elegans and mammalian cells.
Cell
, Vol. 128, (3) : 577-87
Kao, Gautam; Nordenson, Cecilia; Still, Maria; et al.
2006
MAA-1, a novel acyl-CoA-binding protein involved in endosomal vesicle transport in Caenorhabditis elegans.
Mol Biol Cell
, Vol. 17, (10) : 4318-29
Larsen, Morten K; Tuck, Simon; Faergeman, Nils J; et al.
2006
A
Vibrio cholerae
protease needed for killing of
Caenorhabditis elegans
has a role in protection from natural predator grazing
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 103, (24) : 9280-9285
Vaitkevicius, Karolis; Lindmark, Barbro; Ou, Gangwei; et al.
2005
A Caenorhabditis elegans mutant lacking functional nicotinamide nucleotide transhydrogenase displays increased sensitivity to oxidative stress.
Free Radic Biol Med
, Vol. 38, (11) : 1518-25
Arkblad, Eva L; Tuck, Simon; Pestov, Nikolay B; et al.
2005
Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling.
Proc Natl Acad Sci U S A
, Vol. 102, (33) : 11757-62
Rocheleau, Christian E; Rönnlund, Agneta; Tuck, Simon; et al.
2005
C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage.
Cell Death Differ
, Vol. 12, (2) : 153-61
Schumacher, B; Schertel, C; Wittenburg, N; et al.
2005
lin-1 has both positive and negative functions in specifying multiple cell fates induced by Ras/MAP kinase signaling in C. elegans.
Dev Biol
, Vol. 286, (1) : 338-51
Tiensuu, Teresa; Larsen, Morten Krog; Vernersson, Emma; et al.
2004
C. elegans SUR-6/PR55 cooperates with LET-92/protein phosphatase 2A and promotes Raf activity independently of inhibitory Akt phosphorylation sites
Development
, Cambridge: Company of Biologists Limited 2004, Vol. 131, (4) : 755-765
Kao, Gautam; Tuck, Simon; Baillie, David; et al.
2002
Stress response in
Caenorhabditis elegans
caused by optical tweezers: wavelength, power, and time dependence
Biophysical Journal
, Biophysical Society 2002, Vol. 82, (4) : 2224-2231
Leitz, Guenther; Fällman, Erik; Tuck, Simon; et al.
2002
Increased or decreased levels of Caenorhabditis elegans lon-3, a gene encoding a collagen, cause reciprocal changes in body length.
Genetics
, Vol. 161, (1) : 83-97
Nyström, Josefin; Shen, Zai-Zhong; Aili, Margareta; et al.
2000
EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans.
Mol Biol Cell
, Vol. 11, (4) : 1401-19
Furuta, T; Tuck, S; Kirchner, J; et al.
2000
Caenorhabditis elegans lin-25: a study of its role in multiple cell fate specification events involving Ras and the identification and characterization of evolutionarily conserved domains.
Genetics
, Vol. 156, (3) : 1083-96
Nilsson, L; Tiensuu, T; Tuck, S
1999
A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting.
Development
, Vol. 126, (3) : 597-606
Yochem, J; Tuck, S; Greenwald, I; et al.
1998
Caenorhabditis elegans lin-25: cellular focus, protein expression and requirement for sur-2 during induction of vulval fates.
Development
, Vol. 125, (23) : 4809-19
Nilsson, L; Li, X; Tiensuu, T; et al.
TAT-5 and TAT-6 P4-family ATPases regulate the release of extracellular vesicles containing polycystins from Caenorhabditis elegans sensilla
Nilsson, Lars; Rahmani, Shapour; Hubert, Madlen; et al.
Increased release of extracellular vesicles from C. elegans sensilla in mutants with lysosomal defects
Rahmani, Shapour; Tuck, Simon
Activation of cGMP signalling inhibits response behaviour of C. elegans males during mating
Rahmani, Shapour; Tuck, Simon
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