Postdoctoral scholarship (2 years) within regulation of membrane protein transport
The Department of Chemistry is offering a postdoctoral scholarship within regulation of membrane protein transport. The scholarship is full-time for two years with access 1 September 2024 or by agreement. Last day to apply is 15 June 2024.
Project description
The goal of the lab is to determine structural principles in regulation of ATP-dependent transport proteins. This project is aimed specifically at understanding calcium and zinc signalling - with effects on e.g. heart muscle relaxation, stress response in plants, and antimicrobial resistance. We use a wide range of structural biology techniques to determine structures of intermediate states and their kinetics, such as cryo-EM and X-ray solution scattering – a particular focus is on time-resolved methods to track protein dynamics in real time. We have regular access to state-of-the-art cryo-EM and synchrotron facilities in Sweden and France. The project is fully financed by the Kempe foundation.
The project is in an interesting phase with most protocols for production of nanodisc-inserted membrane transporters being established in the lab – which will enable a postdoc to focus more on the structural characterization.
The tax-free 2-year fellowship is funded by the Kempe Foundation, and it amounts to 336 000 SEK per year.
Qualifications
To qualify as a postdoctoral scholarship holder, the postdoctoral fellow is required to have completed a doctoral degree or a foreign degree deemed equivalent to a doctoral degree. This qualification requirements must be fulfilled no later than at the time of the decision about scholarship recipient.
Priority should be given to candidates who completed their doctoral degree, according to what is stipulated in the paragraph above, no later than three years prior. If there are special reasons, candidates who completed their doctoral degree prior to that may also be eligible. Special reasons include absence due to illness, parental leave, appointments of trust in trade union organizations, military service, or similar circumstances, as well as clinical practice or other forms of appointment/assignment relevant to the subject area.
Doctoral degree should be within chemistry, biochemistry, molecular biology, biophysics, structural biology, or similar subject areas.
Additional requirements are:
Practical experience and expertise of protein production and purification.
Good knowledge of the English language, both written and spoken.
Meriting criteria are:
Experience in cryo-EM structure or X-ray crystallography or X-ray solution scattering.
Experience from working with membrane proteins, nanodiscs, and structural biology techniques.
We are looking for candidates who have good collaboration skills, a high degree of independence, and problem-solving analytical ability.
Application
A full application should include:
A cover letter summarizing your qualifications, your scientific interests, your motives for applying to this particular position, and how you feel you meet the essential and meriting criteria (max 2 pages),
Curriculum vitae (CV) with publication list,
Copy of doctoral degree certificate or documentation that clarifies when the degree of doctor is expected to be obtained,
Copies of other diplomas, list of completed academic courses and grades,
Copy of doctoral thesis and up to 5 relevant articles,
Other documents that the applicant wishes to claim.
Contact information to two persons willing to act as references.
Submit your application as a PDF marked with the reference number FS 2.1.6-875-24, both in the file name and in the subject field of the email, to medel@diarie.umu.se. The application should be written in English or Swedish. The application deadline is 15 June 2024.
The position will be located in Umeå, and will begin 1 September 2024 or by agreement.
The Department of Chemistry is one of the largest departments within the Faculty of Science and Technology with approximately 200 employees and strong and expanding research. The Department has four major research areas: Biological Chemistry, IBEAM, Organic chemistry and Technical Chemistry. We are also a strong partner in the KBC, Chemical-Biological Center.
