Sven Bergström

Research qualifications: Docent

Contact

sven.bergstrom@umu.se

+46 90 785 67 26

Works at

Professor at Department of Molecular Biology Section: Research group Sven Bergström

6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå

Cultivation methods of spirochetes from Borrelia burgdorferi sensu lato complex and relapsing fever Borrelia

Journal of Visualized Experiments, Journal of Visualized Experiments 2022, (189)

Berthold, Anne; Faucillion, Marie-Line; Nilsson, Ingela; et al.

Identification of amino acid domains of Borrelia burgdorferi P66 that are surface exposed and important for localization, oligomerization, and porin function of the protein

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2022, Vol. 12

Curtis, Michael W.; Fierros, Christa H.; Hahn, Beth L.; et al.

K₂S₂O₈-mediated coupling of 6-amino-7-aminomethyl-thiazolino-pyridones with aldehydes to construct amyloid affecting pyrimidine-fused thiazolino-2-pyridones

Organic and biomolecular chemistry, The Royal Society of Chemistry 2021, Vol. 19, (44) : 9758-9772

Bharate, Jaideep B.; Ådén, Jörgen; Gharibyan, Anna; et al.

Pathogenesis of relapsing fever

Current Issues in Molecular Biology, Caister Academic Press 2021, Vol. 42 : 519-550

Lopez, Job; Hovius, Joppe W.; Bergström, Sven

A 2-pyridone amide inhibitor of transcriptional activity in Chlamydia trachomatis

Antimicrobial Agents and Chemotherapy, American Society for Microbiology 2021, Vol. 65, (5)

Núñez-Otero, Carlos; Bahnan, Wael; Vielfort, Katarina; et al.

Circumpolar diversification of the Ixodes uriae tick virome

PLoS Pathogens, Public Library Science 2020, Vol. 16, (8)

Pettersson, John H.-O.; Ellström, Patrik; Ling, Jiaxin; et al.

Methyl sulfonamide substituents improve the pharmacokinetic properties of bicyclic 2-pyridone based Chlamydia trachomatis inhibitors

MedChemComm, Royal Society of Chemistry 2019, Vol. 10, (11) : 1966-1987

Kulén, Martina; Núñez-Otero, Carlos; Cairns, Andrew G.; et al.

Joint and unique multiblock analysis of biological data: multiomics malaria study

Faraday discussions, Cambridge: Royal Society of Chemistry 2019, Vol. 218 : 268-283

Surowiec, Izabella; Skotare, Tomas; Sjögren, Rickard; et al.

Microbiological features distinguishing Lyme disease and relapsing fever spirochetes

Wiener Klinische Wochenschrift, Springer 2018, Vol. 130, (15-16) : 484-490

Bergström, Sven; Normark, Johan

Levels of human proteins in plasma associated with acute paediatric malaria

Malaria Journal, BioMed Central (BMC) 2018, Vol. 17

Reuterswärd, Philippa; Bergström, Sofia; Orikiiriza, Judy; et al.

Quantification of run order effect on chromatography: mass spectrometry profiling data

Journal of Chromatography A, Vol. 1568 : 229-234

Surowiec, Izabella; Johansson, Erik; Stenlund, Hans; et al.

Relapsing Fevers: Neglected Tick-Borne Diseases

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2018, Vol. 8

Talagrand-Reboul, Emilie; Boyer, Pierre H.; Bergström, Sven; et al.

Chromosome and Megaplasmid Sequences of Borrelia anserina (Sakharoff 1891), the Agent of Avian Spirochetosis and Type Species of the Genus

Genome Announcements, American Society for Microbiology 2017, Vol. 5, (11)

Elbir, Haitham; Sitlani, Parth; Bergström, Sven; et al.

Thiazolino 2-pyridone amide isosteres as inhibitors of Chlamydia trachomatis infectivity

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2017, Vol. 60, (22) : 9393-9399

Good, James A. D.; Kulén, Martina; Silver, Jim; et al.

Lipid response patterns in acute phase paediatric Plasmodium falciparum malaria

Metabolomics, Vol. 13, (4)

Orikiiriza, Judy; Surowiec, Izabella; Lindquist, Elisabeth; et al.

The oxylipin and endocannabidome responses in acute phase Plasmodium falciparum malaria in children

Malaria Journal, BIOMED CENTRAL LTD 2017, Vol. 16

Surowiec, Izabella; Gouveia-Figueira, Sandra; Orikiiriza, Judy; et al.

Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2016, Vol. 59, (5) : 2094-2108

Good, James A. D.; Silver, Jim; Núñez-Otero, Carlos; et al.

Expansion of the Chlamydia trachomatis inclusion does not require bacterial replication

International Journal of Medical Microbiology, Vol. 305, (3) : 378-382

Engström, Patrik; Bergström, Malin; Alfaro, Astrid C.; et al.

A 2-Pyridone-Amide Inhibitor Targets the Glucose Metabolism Pathway of Chlamydia trachomatis

mBio, Vol. 6, (1)

Engström, Patrik; Krishnan, K. Syam; Ngyuen, Bidong D.; et al.

Integrin binding by Borrelia burgdorferi P66 facilitates dissemination but is not required for infectivity

Cellular Microbiology, Vol. 17, (7) : 1021-1036

Ristow, Laura; Bonde, Mari; Lin, Yi-Pin; et al.

Complete Genome Sequence of Borrelia afzelii K78 and Comparative Genome Analysis

PLOS ONE, Vol. 10, (3)

Schueler, Wolfgang; Bunikis, Ignas; Weber-Lehman, Jacqueline; et al.

Metabolic signature profiling as a diagnostic and prognostic tool in paediatric Plasmodium falciparum malaria

Open Forum Infectious Diseases, Oxford University Press 2015, Vol. 2, (2)

Surowiec, Izabella; Orikiiriza, Judy; Karlsson, Elisabeth; et al.

Study of the protein complex, pore diameter, and pore-forming activity of the Borrelia burgdorferi P13 porin

Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2014, Vol. 289, (27) : 18614-18624

Bárcena-Uribarri, Iván; Thein, Marcus; Barbot, Mariam; et al.

Genome Sequence of the Asiatic Species Borrelia persica

Genome Announcements, Vol. 2, (1)

Elbir, Haitham; Larsson, Pär; Normark, Johan; et al.

Genome sequence of the relapsing fever borreliosis species Borrelia hispanica

Genome Announcements, American Society for Microbiology 2014, Vol. 2, (1)

Elbir, Haitham; Larsson, Pär; Upreti, Mukunda; et al.

Neuroborreliosis: nervous system involvement with borrelia species

Infections of the central nervous system, Wolters Kluwer 2014 : 674-685

Halperin, John J.; Bergström, Sven; Wormser, Gary P.

Maladjusted Host Immune Responses Induce Experimental Cerebral Malaria-Like Pathology in a Murine Borrelia and Plasmodium Co-Infection Model

PLOS ONE, PLOS ONE 2014, Vol. 9, (7)

Normark, Johan; Nelson, Maria; Engström, Patrik; et al.

Early cytokine release in response to live Borrelia burgdorferi sensu lato spirochetes is largely complement independent

PLOS ONE, Vol. 9, (9) : e108013-

Sandholm, Kerstin; Henningsson, Anna J.; Save, Susanne; et al.

Use of Nonelectrolytes Reveals the Channel Size and Oligomeric Constitution of the Borrelia burgdorferi P66 Porin

PLOS ONE, Public Library of Science 2013, Vol. 8, (11) : e78272-

Barcena-Uribarri, Ivan; Thein, Marcus; Maier, Elke; et al.

Mutations in hemG Mediate Resistance to Salicylidene Acylhydrazides, Demonstrating a Novel Link between Protoporphyrinogen Oxidase (HemG) and Chlamydia trachomatis Infectivity

Journal of Bacteriology, Washington DC, USA: American Society for Microbiology 2013, Vol. 195, (18) : 4221-4230

Engström, Patrik; Nguyen, Bidong D.; Normark, Johan; et al.

Complete genome sequence of Borrelia crocidurae

Journal of Bacteriology, American Society of Microbiology, Washington, USA 2012, Vol. 194, (14) : 3723-3724

Elbir, Haitham; Gimenez, Gregory; Robert, Catherine; et al.

Complement activation and phagocytosis in vitro of two strains of Borrelia burgdorferi S.L

Immunobiology, Vol. 217, (11) : 1153-1153

Sandholm, Kerstin; Henningsson, Anna J.; Bergström, Sven; et al.

Adaptive and innate immune responsiveness to Borrelia burgdorferi sensu lato in exposed Asymptomatic children and children with Previous Clinical Lyme Borreliosis

Clinical & Developmental Immunology, Hindawi Publishing Corporation 2012, Vol. 2012 : 294587-294597

Skogman, Barbro H.; Hellberg, Sandra; Ekerfelt, Christina; et al.

DipA, a Pore-Forming Protein in the Outer Membrane of Lyme Disease Spirochetes Exhibits Specificity for the Permeation of Dicarboxylates

PLOS ONE, Vol. 7, (5) : e36523-

Thein, Marcus; Bonde, Mari; Bunikis, Ignas; et al.

Multiplex PCR as a tool for validating plasmid content of Borrelia burgdorferi.

Journal of Microbiological Methods, Vol. 86, (2) : 243-7

Bunikis, Ignas; Bonde, Mari; Kutschan-Bunikis, Sabrina; et al.

Specificity and role of the borrelia burgdorferi CtpA protease in outer membrane protein processing

Journal of Bacteriology, Baltimore: Williams & Wilkins 2011, Vol. 193, (20) : 5759-5765

Kumru, Ozan S.; Bunikis, Ignas; Sorokina, Irina; et al.

Decreased Th1-type inflammatory cytokine expression in the skin is associated with persisting symptoms after treatment of erythema migrans

PLOS ONE, Vol. 6, (3) : e18220-

Sjöwall, Johanna; Fryland, Linda; Nordberg, Marika; et al.

Structure, function and biogenesis of the Borrelia cell envelope

Borrelia, molecular biology, host interactions and pathogenesis, Norfolk, UK: Caister Academic Press 2010 : 139-166

Bergström, Sven; Zückert, Wolfram R

P66 porins are present in both Lyme disease and relapsing fever spirochetes: a comparison of the biophysical properties of P66 porins from six Borrelia species

Biochimica et Biophysica Acta - Biomembranes, Elsevier 2010, Vol. 1798, (6) : 1197-1203

Bárcena-Uribarri, Iván; Thein, Marcus; Sacher, Anna; et al.

Campylobacter volucris sp nov., isolated from black-headed gulls (Larus ridibundus)

International Journal of Systematic and Evolutionary Microbiology, Vol. 60, (8) : 1870-1875

Debruyne, L; Broman, T; Bergström, Sven; et al.

Campylobacter subantarcticus sp nov., isolated from birds in the sub-Antarctic region

International Journal of Systematic and Evolutionary Microbiology, Vol. 60 : 815-819

Debruyne, Lies; Broman, Tina; Bergström, Sven; et al.

Dissemination of spotted fever rickettsia agents in Europe by migrating birds

PLOS ONE, Vol. 5, (1) : e8572-

Elfving, Karin; Olsen, Björn; Bergström, Sven; et al.

A comparative study of RNA and DNA as internal gene expression controls early in the developmental cycle of Chlamydia pneumoniae

FEMS Immunology and Medical Microbiology, Vol. 58, (2) : 244-253

Engström, Patrik; Bailey, Leslie; Önskog, Thomas; et al.

Concomitant Infection Decreases the Malaria Burden but Escalates Relapsing Fever Borreliosis

Infection and Immunity, American Society for Microbiology 2010, Vol. 78, (5) : 1924-1930

Lundqvist, Jenny; Larsson, Christer; Nelson, Maria; et al.

Synthesis and characterization of a multi ring-fused 2-pyridone-based fluorescent scaffold

European Journal of Organic Chemistry, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim 2010, (32) : 6171-6178

Sellstedt, Magnus; Nyberg, Anders; Rosenbaum, Erik; et al.

Phylogenetic analysis of a virulent Borrelia species isolated from patients with relapsing fever

Journal of Clinical Microbiology, Vol. 48, (7) : 2484-2489

Toledo-Arana, A; Anda, P; Escudero, R; et al.

Prevalence and diversity of Borrelia species in ticks that have bitten humans in Sweden

Journal of Clinical Microbiology, Vol. 48, (11) : 4169-4176

Wilhelmsson, Peter; Fryland, Linda; Börjesson, Stefan; et al.

Complex population structure of Lyme borreliosis group spirochete Borrelia garinii in subarctic Eurasia.

PloS one, Vol. 4, (6) : e5841-

Comstedt, Pär; Asokliene, Loreta; Eliasson, Ingvar; et al.

Relapsing fever Borrelia binds to neolacto glycans and mediates rosetting of human erythrocytes.

Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, (46) : 19280-19285

Guo, Betty P; Teneberg, Susann; Münch, Robert; et al.

Risk indicators for the tick Ixodes ricinus and Borrelia burgdorferi sensu lato in Sweden.

Medical and Veterinary Entomology, Vol. 23, (3) : 226-37

Jaenson, T G T; Eisen, L; Comstedt, Pär; et al.

View publications in DiVA

Research groups

Head of research

Sven Bergström Lab