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Sture Forsgren
Contact
E-mail
sture.forsgren@umu.se
Phone
+46 90 786 51 47
Works at
Affiliation
Affiliated as professor emeritus at
Department of Medical and Translational Biology
Section: Teachers A-wing, Teachers D1-wing, Group Patrik Danielson
Location
hus H, Johan Bures väg 12, Biologihuset
Umeå universitet, 901 87 Umeå
Publications
Publications
2019
Neurotrophic factor BDNF is upregulated in soft palate muscles of snorers and sleep apnea patients
Laryngoscope Investigative Otolaryngology (LIO)
, Wiley Periodicals, Inc. 2019, Vol. 4, (1) : 174-180
Shah, Farhan; Forsgren, Sture; Holmlund, Thorbjörn; et al.
2019
Desmin and dystrophin abnormalities in upper airway muscles of snorers and patients with sleep apnea
Respiratory Research
, BioMed Central 2019, Vol. 20
Shah, Farhan; Franklin, Karl A; Holmlund, Thorbjörn; et al.
2018
Apolipoprotein A1 distribution pattern in the human Achilles tendon
Scandinavian Journal of Medicine and Science in Sports
, WILEY 2018, Vol. 28, (5) : 1506-1513
Gaida, James Edmund; Alfredson, Håkan; Scott, A.; et al.
2018
Axon and Schwann Cell Degeneration in Nerves of Upper Airway Relates to Pharyngeal Dysfunction in Snorers and Patients With Sleep Apnea
Chest
, Elsevier 2018, Vol. 154, (5) : 1091-1098
Shah, Farhan; Holmlund, Thorbjörn; Levring Jäghagen, Eva; et al.
2017
Bilateral muscle fiber and nerve influences by TNF-alpha in response to unilateral muscle overuse: studies on TNF receptor expressions
BMC Musculoskeletal Disorders
, Vol. 18, (1)
Renström, Lina; Stål, Per; Song, Yafeng; et al.
2017
Marked expression of TNF receptors in human peritendinous tissues including in nerve fascicles with axonal damage: Studies on tendinopathy and tennis elbow
Journal of Musculoskeletal and Neuronal Interactions - JMNI
, JMNI 2017, Vol. 17, (3) : 226-236
Spang, Christoph; Renström, Lina; Alfredson, Håkan; et al.
2016
A pilot study on biomarkers for tendinopathy: lower levels of serum TNF-alpha and other cytokines in females but not males with Achilles tendinopathy
BMC Sports Science, Medicine and Rehabilitation
, Vol. 8
Gaida, James E.; Alfredson, Håkan; Forsgren, Sture; et al.
2015
Further proof of the existence of a non-neuronal cholinergic system in the human Achilles tendon: Presence of the AChR alpha 7 receptor in tendon cells and cells in the peritendinous tissue
International Immunopharmacology
, Vol. 29, (1) : 195-200
Forsgren, Sture; Alfredson, Håkan; Andersson, Gustav
2015
Serum Levels of Oxylipins in Achilles Tendinopathy: An Exploratory Study
PLOS ONE
, Vol. 10, (4)
Gouveia-Figueira, Sandra; Nording, Malin L.; Gaida, Jamie E.; et al.
2015
Choline acetyltransferase and the nicotinic acetylcholine receptor AChR alpha 7 in experimental myositis
International Immunopharmacology
, Vol. 29, (1) : 189-194
Spang, Christoph; Forsgren, Sture
2015
Marked innervation but also signs of nerve degeneration in between the Achilles and plantaris tendons and presence of innervation within the plantaris tendon in midportion Achilles tendinopathy
Journal of Musculoskeletal and Neuronal Interactions - JMNI
, Vol. 15, (2) : 197-206
Spang, Christoph; Harandi, Vahid M; Alfredsson, Håkan; et al.
2014
Unilateral surgical treatment for patients with midportion Achilles tendinopathy may result in bilateral recovery
British Journal of Sports Medicine
, BMJ Publishing Group 2014, Vol. 48, (19) : 1421-1424
Alfredson, Håkan; Spang, Christoph; Forsgren, Sture
2014
Decreased tumour necrosis factor alpha (tnf-a) in serum of patients with achilles tendinopathy: further evidence against the role of inflammation in the chronic stage
British Journal of Sports Medicine
, BMJ Groups 2014, Vol. 48, (7) : 597-
Gaida, J; Alfredson, Håkan; Forsgren, Sture; et al.
2014
Unilateral muscle overuse causes bilateral changes in muscle fiber composition and vascular supply
PLOS ONE
, Vol. 9, (12) : e116455-
Song, Yafeng; Forsgren, Sture; Liu, Jing-Xia; et al.
2014
Inhibitors of endopeptidase and angiotensin-converting enzyme lead to an amplification of the morphological changes and an upregulation of the substance P system in a muscle overuse model
BMC Musculoskeletal Disorders
, BioMed Central 2014, Vol. 15 : 126-
Song, Yafeng; Stål, Per S; Yu, Ji-Guo; et al.
2013
Bilateral Achilles tendinosis: the similar morphological appearance and the benefit of unilateral treatment has benefits for the contralateral tendon
International journal of experimental pathology (Print)
, Vol. 94, (4) : A18-A18
Alfredson, Håkan; Spang, Christoph; Forsgren, Sture
2013
Nerve ingrowth into tendon tissue in Achilles tendinosis: a Case Report
International journal of experimental pathology (Print)
, Vol. 94, (4) : A8-A8
Bagge, J.; Alfredson, Håkan; Forsgren, Sture
2013
Recent studies using an overuse animal model show that signal substances are highly involved in muscle derangement and muscle inflammation
Proceedings of the International Congress on Sports Science Research and Technology Support
, SciTePress 2013 : 64-70
Forsgren, Sture
2013
In mid-portion Achilles tendinosis the plantaris tendon shows the same tendinosis-like morphological features and expression of the non-neuronal cholinergic system as the Achilles tendon itself
International journal of experimental pathology (Print)
, Vol. 94, (4) : A3-A3
Forsgren, Sture; Spang, Christoph; Alfredson, Håkan
2013
TNF-alpha in an Overuse Muscle Model - Relationship to Muscle Fiber Necrosis/Regeneration, the NK-1 Receptor and an Occurrence of Bilateral Involvement
Journal of Clinical & Cellular Immunology
, Vol. 4, (2)
Renström, Lina; Song, Yafeng; Stål, Per; et al.
2013
Marked effects of tachykinin in myositis both in the experimental side and contralaterally: studies on NK-1 receptor expressions in an animal model
ISRN Inflammation
, Vol. 2013, (907821)
Song, Yafeng; Stål, Per; Yu, Jiguo; et al.
2013
Bilateral increase in expression and concentration of tachykinin in a unilateral rabbit muscle overuse model that leads to myositis
BMC Musculoskeletal Disorders
, BioMed Central 2013, Vol. 14
Song, Yafeng; Stål, Per; Yu, Jiguo; et al.
2013
The plantaris tendon in association with mid-portion Achilles tendinosis: tendinosis-like morphological features and presence of a non-neuronal cholinergic system
Histology and Histopathology
, Vol. 28 : 623-632
Spang, Christoph; Alfredson, Håkan; Ferguson, Mark; et al.
2013
Achilles tendinopathy is a troublesome sports-related condition involving blood vessel ingrowth into the tendon tissue: Studies on the adjacent plantaris tendon and the peritendinous connective tissue suggest that TNF-alpha can be highly involved in the vascular and tissue changes
Proceedings of the International Congress on Sports Science Research and Technology Support
, SciTePress 2013 : 45-50
Spang, Christoph; Alfredson, Håkan; Forsgren, Sture
2012
In situ hybridization studies favouring the occurrence of a local production of BDNF in the human Achilles tendon
Histology and Histopathology
, Vol. 27, (9) : 1239-1246
Bagge, Johan; Danielson, Patrik; Forsgren, Sture
2012
The Cholinergic System Can Be of Unexpected Importance in Osteoarthritis
Priciples of Osteoarthritis, Its definition, character, derivation and modality-related recognition
, InTech 2012 : 461-472
Forsgren, Sture
2012
Presence of ChAT mRNA and a very marked alpha 7nAChR immunoreaction in the synovial lining layer of the knee joint
Life Sciences
, Elsevier 2012, Vol. 91, (21-22) : 1043-1047
Forsgren, Sture
2012
TNF-Alpha in the Locomotor System beyond Joints: High Degree of Involvement in Myositis in a Rabbit Model.
International Journal of Rheumatology
, Vol. 2012 : 637452-
Forsgren, Sture; Renström, Lina; Purdam, Craig; et al.
2012
Evidence of the TNF-α system in the human Achilles tendon: expression of TNF-α and TNF receptor at both protein and mRNA levels in the tenocytes
Cells Tissues Organs
, S. Karger 2012, Vol. 196, (4) : 339-352
Gaida, James Edmund; Bagge, Johan; Purdam, Craig; et al.
2012
Epithelial Expression of Vasoactive Intestinal Peptide in Ulcerative Colitis: Down-Regulation in Markedly Inflamed Colon
Digestive Diseases and Sciences
, Dordrecht: Springer 2012, Vol. 57, (2) : 303-310
Jonsson, Maria; Norrgard, Orjan; Forsgren, Sture
2012
Effects on contralateral muscles after unilateral electrical muscle stimulation and exercise
PLOS ONE
, Public Library Science 2012, Vol. 7, (12) : e52230-
Song, Yafeng; Forsgren, Sture; Yu, Jiguo; et al.
2012
VGluT2 and NMDAR1 expression in cells in the inflammatory infiltrates in experimentally induced myositis: evidence of local glutamate signaling suggests autocrine/paracrine effects in an overuse injury model
Inflammation
, Vol. 35, (1) : 39-48
Spang, Christoph; Scott, Alexander; Danielson, Patrik; et al.
2011
Ultrasound and doppler-guided artthroscopic shaving for the treatment of patellar tendinopathy/jumper´s knee: biological background and description of method
Anterior knee pain and patellar instability
, London: Springer London 2011 : 367-371
Alfredson, Håkan; Willberg, Lotta; Öhberg, Lars; et al.
2011
Substance P accelerates hypercellularity and angiogenesis in tendon tissue and enhances paratendinitis in response to Achilles tendon overuse in a tendinopathy model
British Journal of Sports Medicine
, Loughborough: British Assoc. of Sport and Medicine 2011, Vol. 45, (13) : 1017-1022
Andersson, Gustav; Backman, Ludvig; Scott, Alexander; et al.
2011
Tenocyte hypercellularity and vascular proliferation in a rabbit model of tendinopathy: contralateral effects suggest the involvement of central neuronal mechanisms
British Journal of Sports Medicine
, Vol. 45, (5) : 399-406
Andersson, Gustav; Forsgren, Sture; Scott, Alexander; et al.
2011
Endogenous substance P production in the Achilles tendon increases with loading in an in vivo model of tendinopathy: peptidergic elevation preceding tendinosis-like tissue changes
Journal of Musculoskeletal and Neuronal Interactions - JMNI
, International Society of Musculoskeletal and Neuronal Interactions 2011, Vol. 11, (2) : 133-140
Backman, Ludvig; Andersson, Gustav; Wennstig, Gabriel; et al.
2011
Physical activity level in Achilles tendinosis is associated with blood levels of pain-related factors: a pilot study
Scandinavian Journal of Medicine and Science in Sports
, Vol. 21, (6) : E430-E438
Bagge, Johan; Gaida, JE; Danielson, Patrik; et al.
2011
Increased expression of cannabinoid CB(1) receptors in achilles tendinosis
PLOS ONE
, San Francisco, CA: Public Library of Science 2011, Vol. 6, (9) : e24731-
Björklund, Emmelie; Forsgren, Sture; Alfredson, Håkan; et al.
2011
Measurements in the Blood of BDNF for RA Patients and in Response to Anti-TNF Treatment Help Us to Clarify the Magnitude of Centrally Related Pain and to Explain the Relief of This Pain upon Treatment
International Journal of Inflammation
, Sage-Hindawi 2011, Vol. 2011 : 650685-
Forsgren, Sture; Grimsholm, Ola; Dalén, Tore; et al.
2009
Unexpected presence of the neurotrophins NGF and BDNF and the neurotrophin receptor p75 in the tendon cells of the human Achilles tendon
Histology and Histopathology
, Vol. 24, (7) : 839-848
Bagge, Johan; Lorentzon, Ronny; Alfredson, Håkan; et al.
2009
Presence of the neuropeptide Y 1 receptor in tenocytes and blood vessel walls in the human Achilles tendon
British Journal of Sports Medicine
, BMJ Publishing Group 2009, Vol. 43, (13) : 1136-1142
Bjur, Dennis; Alfredson, Håkan; Forsgren, Sture
2009
New data favouring that neurotrophins are of importance in arthritis
Arthritis Research & Therapy
, Vol. 11, (4) : 122-
Forsgren, Sture
2009
Novel information on the non-neuronal cholinergic system in orthopedics provides new possible treatment strategies for inflammatory and degenerative diseases
Orthopedic Reviews
, Vol. 1, (1) : 39-46
Forsgren, Sture; Alfredson, Håkan; Bjur, Dennis; et al.
2008
Effect of betamethasone on the degree of macrophage recruitment and nerve growth factor receptor p75 immunoreaction during recovery of the sciatic nerve after injury: an experimental study in rats.
British Journal of Oral & Maxillofacial Surgery
, Vol. 46, (6) : 455-9
Al-Bishri, Awwad; Forsgren, Sture; Al-Thobaiti, Yasser; et al.
2008
Presence of substance P and the neurokinin-1 receptor in tenocytes of the human Achilles tendon
Regulatory Peptides
, Vol. 150, (1-3) : 81-87
Andersson, Gustav; Danielson, Patrik; Alfredson, Håkan; et al.
2008
Immunohistochemical and in situ hybridization observations favor a local catecholamine production in the human Achilles tendon
Histology and Histopathology
, Vol. 23, (2) : 197-208
Bjur, Dennis; Danielson, Patrik; Alfredson, Håkan; et al.
2008
Presence of a non-neuronal cholinergic system and occurrence of up- and down-regulation in expression of M2 muscarinic acetylcholine receptors: new aspects of importance regarding Achilles tendon tendinosis (tendinopathy)
Cell and Tissue Research
, Vol. 331, (2) : 385-400
Bjur, Dennis; Danielson, Patrik; Alfredson, Håkan; et al.
2008
Marked sympathetic component in the perivascular innervation of the dorsal paratendinous tissue of the patellar tendon in arthroscopically treated tendinosis patients.
Knee Surgery, Sports Traumatology, Arthroscopy
, Vol. 16, (6) : 621-6
Danielson, Patrik; Andersson, Gustav; Alfredson, Håkan; et al.
2008
Expression patterns of neurotrophins and neurotrophin receptors in articular chondrocytes and inflammatory infiltrates in knee joint arthritis.
Cells, tissues, organs
, Vol. 188, (3) : 299-309
Grimsholm, Ola; Guo, Yongzhi; Ny, Tor; et al.
2008
Unexpected finding of a marked non-neuronal cholinergic system in human knee joint synovial tissue.
Neuroscience Letters
, Vol. 442, (2) : 128-33
Grimsholm, Ola; Rantapää-Dahlqvist, Solbritt; Dalén, Tore; et al.
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