Simon Tuck

Research qualifications: Docent

Contact

simon.tuck@umu.se

+46 90 786 67 87

Works at

Professor at Department of Medical and Translational Biology Section: Section for Molecular Medicine

hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå

Homepage

LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes

Communications Biology, Springer Nature 2021, Vol. 4, (1)

Herdenberg, Carl; Mutie, Pascal; Billing, Ola; et al.

C. elegans TAT-6, a putative aminophospholipid translocase, is expressed in sujc cells in the hermaphrodite gonad

microPublication biology

Nilsson, Lars; Rahmani, Shapour; Tuck, Simon

EGL-4 promotes turning behavior of C. elegans males during mating

microPublication biology

Rahmani, Shapour; Tuck, Simon

Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems

Molecular Nutrition & Food Research, WILEY 2019, Vol. 63, (9)

Rohn, Isabelle; Raschke, Stefanie; Aschner, Michael; et al.

Flagella-mediated secretion of a novel Vibrio cholerae cytotoxin affecting both vertebrate and invertebrate hosts

Communications Biology, Springer Nature Publishing AG 2018, Vol. 1

Dongre, Mitesh; Singh, Bhupender; Aung, Kyaw Min; et al.

Selenium species-dependent toxicity, bioavailability and metabolic transformations in Caenorhabditis elegans

Metallomics, Royal Society of Chemistry 2018, Vol. 10, (6) : 818-827

Rohn, Isabelle; Marschall, Talke Anu; Kroepfl, Nina; et al.

Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses

PLOS Genetics, Vol. 13, (7)

Navarro-Gonzalez, Carmen; Moukadiri, Ismail; Villarroya, Magda; et al.

Fourier transform infrared microspectroscopy for the analysis of the biochemical composition of C. elegans worms

Worm, Taylor & Francis 2016, Vol. 5, (1)

Sheng, Ming; Gorzsás, András; Tuck, Simon

Aberrant Fat Metabolism in Caenorhabditis elegans Mutants with Defects in the Defecation Motor Program

PLOS ONE, PLOS one 2015, Vol. 10, (4)

Sheng, Ming; Hosseinzadeh, Ava; Muralidharan, Somsundar Veppil; et al.

The control of cell growth and body size in Caenorhabditis elegans

Experimental Cell Research, Vol. 321, (1) : 71-76

Tuck, Simon

S6K links cell fate, cell cycle and nutrient response in C. elegans germline stem/progenitor cells.

Development, Vol. 139, (5) : 859-870

Korta, Dorota Z; Tuck, Simon; Hubbard, E Jane Albert

Tissue- and paralogue-specific functions of acyl-CoA-binding proteins in lipid metabolism in Caenorhabditis elegans

Biochemical Journal, Vol. 437, (2) : 231-241

Elle, Ida C; Simonsen, Karina T; Olsen, Louise C B; et al.

Caenorhabditis elegans Numb Inhibits Endocytic Recycling by Binding TAT-1 Aminophospholipid Translocase

Traffic: the International Journal of Intracellular Transport, Malden: Wiley-Blackwell 2011, Vol. 12, (12) : 1839-1849

Nilsson, Lars; Jonsson, Eva; Tuck, Simon

Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans

Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, (3) : 1064-1069

Stenvall, Jörgen; Fierro-González, Juan Carlos; Swoboda, Peter; et al.

Extracellular vesicles: budding regulated by a phosphatidylethanolamine translocase

Current Biology, Vol. 21, (24) : R988-R990

Tuck, Simon

TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans

Molecular Biology of the Cell, American Society for Cell Biology 2010, Vol. 21, (13) : 2285-2296

Chotard, Laëtitia; Mishra, Ashwini K; Sylvain, Marc-André; et al.

Defects in tRNA modification associated with neurological and developmental dysfunctions in Caenorhabditis elegans elongator mutants

PLoS genetics, Vol. 5, (7) : e1000561-

Chen, Changchun; Tuck, Simon; Byström, Anders S

The C. elegans P4-ATPase TAT-1 regulates Lysosome Biogenesis and Endocytosis

Traffic: the International Journal of Intracellular Transport, Vol. 10, (1) : 88-100

Ruaud, Anne-Françoise; Nilsson, Lars; Richard, Fabrice; et al.

Caenorhabditis elegans num-1 negatively regulates endocytic recycling

Genetics, Vol. 179 : 375-387

Nilsson, Lars; Conradt, Barbara; Ruaud, Anne-Françoise; et al.

Diet-dependent depletion of queuosine in tRNAs in Caenorhabditis elegans does not lead to a developmental block.

J Biosci, Vol. 32, (4) : 747-54

Gaur, Rahul; Björk, Glenn; Tuck, Simon; et al.

ASNA-1 positively regulates insulin secretion in C. elegans and mammalian cells.

Cell, Vol. 128, (3) : 577-87

Kao, Gautam; Nordenson, Cecilia; Still, Maria; et al.

MAA-1, a novel acyl-CoA-binding protein involved in endosomal vesicle transport in Caenorhabditis elegans.

Mol Biol Cell, Vol. 17, (10) : 4318-29

Larsen, Morten K; Tuck, Simon; Faergeman, Nils J; et al.

A Vibrio cholerae protease needed for killing of Caenorhabditis elegans has a role in protection from natural predator grazing

Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, (24) : 9280-9285

Vaitkevicius, Karolis; Lindmark, Barbro; Ou, Gangwei; et al.

A Caenorhabditis elegans mutant lacking functional nicotinamide nucleotide transhydrogenase displays increased sensitivity to oxidative stress.

Free Radic Biol Med, Vol. 38, (11) : 1518-25

Arkblad, Eva L; Tuck, Simon; Pestov, Nikolay B; et al.

Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling.

Proc Natl Acad Sci U S A, Vol. 102, (33) : 11757-62

Rocheleau, Christian E; Rönnlund, Agneta; Tuck, Simon; et al.

C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage.

Cell Death Differ, Vol. 12, (2) : 153-61

Schumacher, B; Schertel, C; Wittenburg, N; et al.

lin-1 has both positive and negative functions in specifying multiple cell fates induced by Ras/MAP kinase signaling in C. elegans.

Dev Biol, Vol. 286, (1) : 338-51

Tiensuu, Teresa; Larsen, Morten Krog; Vernersson, Emma; et al.

C. elegans SUR-6/PR55 cooperates with LET-92/protein phosphatase 2A and promotes Raf activity independently of inhibitory Akt phosphorylation sites

Development, Cambridge: Company of Biologists Limited 2004, Vol. 131, (4) : 755-765

Kao, Gautam; Tuck, Simon; Baillie, David; et al.

Stress response in Caenorhabditis elegans caused by optical tweezers: wavelength, power, and time dependence

Biophysical Journal, Biophysical Society 2002, Vol. 82, (4) : 2224-2231

Leitz, Guenther; Fällman, Erik; Tuck, Simon; et al.

Increased or decreased levels of Caenorhabditis elegans lon-3, a gene encoding a collagen, cause reciprocal changes in body length.

Genetics, Vol. 161, (1) : 83-97

Nyström, Josefin; Shen, Zai-Zhong; Aili, Margareta; et al.

EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans.

Mol Biol Cell, Vol. 11, (4) : 1401-19

Furuta, T; Tuck, S; Kirchner, J; et al.

Caenorhabditis elegans lin-25: a study of its role in multiple cell fate specification events involving Ras and the identification and characterization of evolutionarily conserved domains.

Genetics, Vol. 156, (3) : 1083-96

Nilsson, L; Tiensuu, T; Tuck, S

A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting.

Development, Vol. 126, (3) : 597-606

Yochem, J; Tuck, S; Greenwald, I; et al.

Caenorhabditis elegans lin-25: cellular focus, protein expression and requirement for sur-2 during induction of vulval fates.

Development, Vol. 125, (23) : 4809-19

Nilsson, L; Li, X; Tiensuu, T; et al.

TAT-5 and TAT-6 P4-family ATPases regulate the release of extracellular vesicles containing polycystins from Caenorhabditis elegans sensilla

Nilsson, Lars; Rahmani, Shapour; Hubert, Madlen; et al.

Increased release of extracellular vesicles from C. elegans sensilla in mutants with lysosomal defects

Rahmani, Shapour; Tuck, Simon

Activation of cGMP signalling inhibits response behaviour of C. elegans males during mating

Rahmani, Shapour; Tuck, Simon

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Research groups

Head of research

Simon Tuck lab