Jörgen Johansson

How can bacteria understand where they are and coordinate their ability to cause disease? To understand this, Professor Jörgen Johansson is studying the bacterium Listeria monocytogenes.

Research qualifications: Docent

Contact

jorgen.johansson@umu.se

+46 90 785 25 35

Works at

Professor at Department of Molecular Biology Section: Research group Jörgen Johansson

6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå

The virulence and infectivity of Listeria monocytogenes are not substantially altered by elevated SigB activity

Infection and Immunity, American Society for Microbiology 2023, Vol. 91, (6)

de Oliveira, Ana H.; Tiensuu, Teresa; Guerreiro, Duarte; et al.

Structural insights into CodY activation and DNA recognition

Nucleic Acids Research, Oxford University Press 2023, Vol. 51, (14) : 7631-7648

Hainzl, Tobias; Bonde, Mari; Almqvist, Fredrik; et al.

Super-resolving microscopy reveals the localizations and movement dynamics of stressosome proteins in Listeria monocytogenes

Communications Biology, Nature Publishing Group 2023, Vol. 6, (1)

Tran, Buu Minh; Linnik, Dmitrii Sergeevich; Punter, Christiaan Michiel; et al.

A highly substituted ring-fused 2-pyridone compound targeting PrfA and the efflux regulator BrtA in listeria monocytogenes

mBio, American Society for Microbiology 2023, Vol. 14, (3)

Tükenmez, Hasan; Singh, Pardeep; Sarkar, Souvik; et al.

Listeria monocytogenes requires the RsbX protein to prevent SigB-activation under non-stressed conditions

Journal of Bacteriology, American Society for Microbiology 2022, Vol. 204, (1)

de Oliveira, Ana Henriques; Tiensuu, Teresa; Guerreiro, Duarte N.; et al.

Acid stress signals are integrated into the σb-dependent general stress response pathway via the stressosome in the food-borne pathogen Listeria monocytogenes

PLoS Pathogens, Public Library of Science 2022, Vol. 18, (3)

Guerreiro, Duarte N.; Pucciarelli, M. Graciela; Tiensuu, Teresa; et al.

Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes

Nucleic Acids Research, Oxford University Press 2022, Vol. 50, (19) : 11285-11300

Koller, Timm O.; Turnbull, Kathryn Jane; Vaitkevicius, Karolis; et al.

Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics

Proceedings of the National Academy of Sciences of the United States of America, PNAS 2022, Vol. 119, (43)

Nye, Taylor M.; Tükenmez, Hasan; Singh, Pardeep; et al.

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages

PLoS Pathogens, Public Library Science 2022, Vol. 18, (1)

Tran, Thao Thanh; Mathmann, Carmen D.; Gatica-Andrades, Marcela; et al.

Complete Genome Sequence of the Uropathogenic Methicillin-Resistant Staphylococcus aureus Strain MRSA-1369

Microbiology Resource Announcements, American Society for Microbiology 2022, Vol. 11, (10)

Tükenmez, Hasan; Nye, Taylor M.; Bonde, Mari; et al.

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens

Nature Communications, Springer Nature 2021, Vol. 12, (1)

Crowe-McAuliffe, Caillan; Murina, Victoriia; Turnbull, Kathryn Jane; et al.

Mild Stress Conditions during Laboratory Culture Promote the Proliferation of Mutations That Negatively Affect Sigma B Activity in Listeria monocytogenes

Journal of Bacteriology, American Society for Microbiology 2020, Vol. 202, (9)

Guerreiro, Duarte N.; Wu, Jialun; Dessaux, Charlotte; et al.

A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes

Journal of Bacteriology, American Society for Microbiology 2020, Vol. 202, (11)

Hansen, Sabine; Hall, Michael; Grundström, Christin; et al.

An mRNA-mRNA Interaction Couples Expression of a Virulence Factor and Its Chaperone in Listeria monocytogenes

Cell Reports, cell press 2020, Vol. 30, (12) : 4027-+

Ignatov, Dmitriy; Vaitkevicius, Karolis; Durand, Sylvain; et al.

Generation of Sequencing Libraries for Structural Analysis of Bacterial 5′ UTRs

STAR Protocols, Vol. 1, (2)

Ignatov, Dmitriy; Vaitkevicius, Karolis; Johansson, Jörgen

Feeling the heat at the millennium: thermosensors playing with fire

Molecular Microbiology, John Wiley & Sons 2020, Vol. 113, (3) : 588-592

Mandin, Pierre; Johansson, Jörgen

Regulation of Listeria monocytogenes Virulence

Microbiology Spectrum, American Society for Microbiology 2019, Vol. 7, (4)

Johansson, Jörgen; Freitag, Nancy E.

The σ^B-dependent regulatory sRNA Rli47 represses isoleucine biosynthesis in Listeria monocytogenes through a direct interaction with the ilvA transcript

RNA Biology, Taylor & Francis 2019, Vol. 16, (10) : 1424-1437

Marinho, Catarina M.; Dos Santos, Patricia T.; Kallipolitis, Birgitte H.; et al.

Urea dilution of serum for reproducible anti-HSV1 IgG avidity index

BMC Infectious Diseases, BioMed Central 2019, Vol. 19

Olsson, Jan; Johansson, Jörgen; Honkala, Emma; et al.

Flick of a switch: regulatory mechanisms allowing Listeria monocytogenes to transition from a saprophyte to a killer

Microbiology, MICROBIOLOGY SOC 2019, Vol. 165, (8) : 819-833

Tiensuu, Teresa; Guerreiro, Duarte N.; de Oliveira, Ana Henriques; et al.

Structure-based design of inhibitors targeting PrfA, the master virulence regulator of Listeria monocytogenes

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2018, Vol. 61, (9) : 4165-4175

Kulén, Martina; Lindgren, Marie; Hansen, Sabine; et al.

Role in virulence of phospholipases, listeriolysin O and listeriolysin S from epidemic Listeria monocytogenes using the chicken embryo infection model

Veterinary research (Print), BioMed Central 2018, Vol. 49

Quereda, Juan J.; Andersson, Christopher; Cossart, Pascale; et al.

RNA-mediated signal perception in pathogenic bacteria

Wiley Interdisciplinary Reviews-RNA, John Wiley & Sons 2017, Vol. 8, (6)

Ignatov, Dmitriy; Johansson, Jörgen

Two Are Better Than One: Dual Targeting of Riboswitches by Metabolite Analogs

Cell Chemical Biology, Vol. 24, (5) : 535-537

Krajewski, Stefanie Sandra; Ignatov, Dmitry; Johansson, Jörgen

Antibacterial and antivirulence effect of 6-N-hydroxylaminopurine in Listeria monocytogenes

Nucleic Acids Research, Vol. 45, (4) : 1914-1924

Krajewski, Stefanie Sandra; Isoz, Isabelle; Johansson, Jörgen

A Novel Role of Listeria monocytogenes Membrane Vesicles in Inhibition of Autophagy and Cell Death

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2017, Vol. 7

Vdovikova, Svitlana; Luhr, Morten; Szalai, Paula; et al.

Attenuating Listeria monocytogenes virulence by targeting the regulatory protein PrfA

Cell chemical biology, Vol. 23, (3) : 404-414

Good, James A. D.; Andersson, Christopher; Hansen, Sabine; et al.

Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria

Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, (51) : 14733-14738

Hall, Michael; Grundström, Christin; Begum, Afshan; et al.

Battling the bureaucracy hydra

Science, Vol. 351, (6272) : 530-530

Johansson, Jörgen

Uptake and Metabolism of Antibiotics Roseoflavin and 8-Demethyl-8-Aminoriboflavin in Riboflavin-Auxotrophic Listeria monocytogenes

Journal of Bacteriology, Vol. 198, (23) : 3233-3243

Matern, Andreas; Pedrolli, Danielle; Großhennig, Stephanie; et al.

RNA helicase important for Listeria monocytogenes hemolytic activity and virulence factor expression

Infection and Immunity, American Society for Microbiology 2016, Vol. 84, (1) : 67-76

Netterling, Sakura; Bäreclev, Caroline; Vaitkevicius, Karolis; et al.

Blue-Light Inhibition of Listeria monocytogenes Growth Is Mediated by Reactive Oxygen Species and Is Influenced by sigma(B) and the Blue-Light Sensor Lmo0799

Applied and Environmental Microbiology, Vol. 82, (13) : 4017-4027

O'Donoghue, Beth; NicAogain, Kerrie; Bennett, Claire; et al.

Using the chicken embryo to assess virulence of Listeria monocytogenes and to model other microbial infections

Nature Protocols, Nature Publishing Group 2015, Vol. 10, (8) : 1155-1164

Andersson, Christopher; Gripenland, Jonas; Johansson, Jörgen

The multicopy sRNA LhrC controls expression of the oligopeptide-binding protein OppA in Listeria monocytogenes

RNA Biology, [Sievers, Susanne; Lund, Anja; Menendez-Gil, Pilar; Nielsen, Aaraby; Storm Mollerup, Maria; Lambert Nielsen, Stine; Buch Larsson, Pernille; Borch-Jensen, Jonas; Kallipolitis, Birgitte Haahr] Univ Southern Denmark, Dept Biochem & Mol Biol, Odense, Denmark. [Sievers, Susanne] Ernst Moritz Arndt Univ Greifswald, Inst Microbiol, Greifswald, Germany. [Johansson, Joergen] Umea Univ, Dept Mol Biol, Umea, Sweden.: 2015, Vol. 12, (9) : 985-997

Sievers, Susanne; Lund, Anja; Menendez-Gil, Pilar; et al.

DExD-box RNA-helicases in Listeria monocytogenes are important for growth, ribosomal maturation, rRNA processing and virulence factor expression

RNA Biology, Vol. 11, (11) : 1458-1467

Bäreclev, Caroline; Vaitkevicius, Karolis; Netterling, Sakura; et al.

Exploring the chicken embryo as a possible model for studying Listeria monocytogenes pathogenicity

Frontiers in Cellular and Infection Microbiology, Vol. 4

Gripenland, Jonas; Andersson, Christopher; Johansson, Jörgen

Inducible CYP2J2 and its product 11,12-EET promotes bacterial phagocytosis: a role for CYP2J2 deficiency in the pathogenesis of Crohn's disease?

PLOS ONE, Public Library of Science 2013, Vol. 8, (9)

Byström, Jonas; Thomson, Scott J.; Johansson, Jörgen; et al.

A riboswitch-regulated antisense RNA in Listeria monocytogenes

Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, (32) : 13132-13137