Ikenna Obi

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Works at

Staff scientist at Department of Medical Biochemistry and Biophysics Section: Nasim Sabouri group

KB. A5, Campus, Umeå Umeå universitet, 901 87 Umeå

A new G-quadruplex-specific photosensitizer inducing genome instability in cancer cells by triggering oxidative DNA damage and impeding replication fork progression

Nucleic Acids Research, Oxford University Press 2023, Vol. 51, (12) : 6264-6285

Deiana, Marco; Andrés Castán, José María; Josse, Pierre; et al.

A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures

ACS Chemical Biology, American Chemical Society (ACS) 2021, Vol. 16, (8) : 1365-1376

Deiana, Marco; Obi, Ikenna; Andréasson, Måns; et al.

The RGG domain in the C-terminus of the DEAD box helicases Dbp2 and Ded1 is necessary for G-quadruplex destabilization

Nucleic Acids Research, Oxford University Press 2021, Vol. 49, (14) : 8339-8354

Yan, Kok-Phen; Obi, Ikenna; Sabouri, Nasim

A Site-Specific Self-Assembled Light-up Rotor Probe for Selective Recognition and Stabilization of c-MYC G-Quadruplex DNA

Nanoscale, Royal Society of Chemistry 2020, Vol. 12, (24) : 12950-12957

Deiana, Marco; Chand, Karam; Jamroskovic, Jan; et al.

A Light‐up Logic Platform for Selective Recognition of Parallel G‐Quadruplex Structures via Disaggregation‐Induced Emission

Angewandte Chemie International Edition, Wiley-VCH Verlagsgesellschaft 2020, Vol. 59, (2) : 896-902

Deiana, Marco; Chand, Karam; Jamroskovic, Jan; et al.

Unravelling the cellular emission fingerprint of the benchmark G-quadruplex-interactive compound Phen-DC3

Chemical Communications, Royal Society of Chemistry 2020, Vol. 56, (91) : 14251-14254

Deiana, Marco; Jamroskovic, Jan; Obi, Ikenna; et al.

Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex Stabilization

Journal of the American Chemical Society, Vol. 142, (6) : 2876-2888

Jamroskovic, Jan; Doimo, Mara; Chand, Karam; et al.

Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication

Nucleic Acids Research, Oxford University Press 2020, Vol. 48, (19) : 10998-11015

Obi, Ikenna; Rentoft, Matilda; Singh, Vandana; et al.

Identification of putative G-quadruplex DNA structures in S. pombe genome by quantitative PCR stop assay

DNA Repair, Vol. 82

Jamroskovic, Jan; Obi, Ikenna; Movahedi, Anahita; et al.

The Yersinia pseudotuberculosis Cpx envelope stress system contributes to transcriptional activation of rovM

Virulence, Taylor & Francis Group 2019, Vol. 10, (1) : 37-57

Thanikkal, Edvin J.; Kumar Gahlot, Dharmender; Liu, Junfa; et al.

Helicobacter pylori Outer Membrane Vesicles Protect the Pathogen From Reactive Oxygen Species of the Respiratory Burst

Frontiers in Microbiology, Frontiers Media S.A. 2018, Vol. 9

Lekmeechai, Sujinna; Su, Yu-Ching; Brant, Marta; et al.

BabA dependent binding of Helicobacter pylori to human gastric mucins cause aggregation that inhibits proliferation and is regulated via ArsS

Scientific Reports, Vol. 7

Skoog, Emma C.; Padra, Medea; Åberg, Anna; et al.

Uptake of Helicobacter pylori vesicles is facilitated by clathrin-dependent and clathrin-independent endocytic pathways

mBio, Vol. 5, (3) : e00979-14-

Olofsson, Annelie; Nygård Skalman, Lars; Obi, Ikenna; et al.

Demarcating SurA activities required for outer membrane targeting of Yersinia pseudotuberculosis adhesins

Infection and Immunity, Washington: American Society for Microbiology 2013, Vol. 81, (7) : 2296-2308

Obi, Ikenna; Francis, Matthew

Elevated CpxR~P levels repress the Ysc-Yop type III secretion system of Yersinia pseudotuberculosis

Research in Microbiology, Elsevier: 2012, Vol. 163, (8) : 518-530

Liu, Junfa; Thanikkal, Edvin; Obi, Ikenna; et al.

Phosphorylated CpxR Restricts Production of the RovA Global Regulator in Yersinia pseudotuberculosis

PLOS ONE, Public Library of Science 2011, Vol. 6, (8) : e23314-

Liu, Junfa; Obi, Ikenna R; Thanikkal, Edvin J; et al.

Varying dependency of periplasmic peptidylprolyl cis-trans isomerases in promoting Yersinia pseudotuberculosis stress tolerance and pathogenicity

Biochemical Journal, United Kingdom: Portland Press Limited 2011, Vol. 439, (2) : 321-332

Obi, Ikenna; Nordfelth, Roland; Francis, Matthew

The Yersinia pseudotuberculosis Cpx envelope stress system contributes to transcription activation of rovM

Thanikkal, Edvin; Obi, Ikenna; Liu, Junfa; et al.

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Research groups

Group member

Nasim Sabouri