Ana Virel

Associate Professor and Docent in Histology and Cell Biology.

Department of Medical and Translational Biology.

Research qualifications: Docent

Educational qualifications: Recognised university teacher

Contact

ana.virel@umu.se

+46 90 786 77 93

Works at

Associate professor at Department of Medical and Translational Biology Section: Teachers D1-wing, Group Ana Virel

hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå

Associate Professor at the Department of Medical and Translational Biology.

My research focuses on identifying potential factors contributing to dopamine decline and finding possible therapeutic treatments capable of restoring the compromised dopamine system.

N-acetylcysteine increases dopamine release and prevents the deleterious effects of 6-OHDA on the expression of VMAT2, α-synuclein, and tyrosine hydroxylase

Neurological Research, Taylor & Francis Group 2024, Vol. 46, (5) : 406-415

El-Habta, Roine; af Bjerkén, Sara; Virel, Ana

Amphetamine-induced dopamine release in rat: Whole-brain spatiotemporal analysis with [¹¹C]raclopride and positron emission tomography

Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2024, Vol. 44, (3) : 434-445

Johansson, Jarkko; Ericsson, Madelene; Axelsson, Jan; et al.

N-acetylcysteine decreases dopamine transporter availability in the non-lesioned striatum of the 6-OHDA hemiparkinsonian rat

Neuroscience Letters, Elsevier 2022, Vol. 770

Virel, Ana; Johansson, Jarkko; Axelsson, Jan; et al.

Noradrenaline is crucial for the substantia nigra dopaminergic cell maintenance

Neurochemistry International, Elsevier 2019, Vol. 131

af Bjerkén, Sara; Stenmark Persson, Rasmus; Barkander, Anna; et al.

H-1 NMR profiling of the 6-OHDA parkinsonian rat brain reveals metabolic alterations and signs of recovery after N-acetylcysteine treatment

Molecular and Cellular Neuroscience, Vol. 98 : 131-139

Virel, Ana; Dudka, Ilona; Laterveer, Rutger; et al.

An altered blood–brain barrier contributes to brain iron accumulation and neuroinflammation in the 6-OHDA rat model of Parkinson's disease

Neuroscience, Elsevier 2017, Vol. 362 : 141-151

Olmedo-Díaz, Sonia; Estévez-Silva, Héctor; Orädd, Greger; et al.

Magnetic resonance imaging as a tool to image neuroinflammation in a rat model of Parkinson's disease: phagocyte influx to the brain is promoted by bilberry-enriched diet

European Journal of Neuroscience, Vol. 42, (10) : 2761-2771

Virel, Ana; Rehnmark, Anna; Orädd, Greger; et al.

Magnetic Resonance Imaging (MRI) to Study Striatal Iron Accumulation in a Rat Model of Parkinson's Disease

PLOS ONE, Vol. 9, (11) : e112941-

Virel, Ana; Faergemann, Erik; Orädd, Greger; et al.

Neuroinflammation Using MRI: Phagocytes From Blood to Brain With the Help of Bilberries

Cell Transplantation, Vol. 22, (5) : 917-917

Strömberg, Ingrid; Rehnmark, Anna; Orädd, Greger; et al.

Quantification of prothrombin in human plasma amplified by autocatalytic reaction

Analytical Chemistry, American Chemical Society (ACS) 2012, Vol. 84, (5) : 2380-2387

Virel, Ana; Saa, Laura; Pavlov, Valeri

Analytical applications of enzymatic growth of quantum dots

Chemistry - A European Journal, Wiley-VCH Verlagsgesellschaft 2010, Vol. 16, (21) : 6187-6192

Saa, Laura; Virel, Ana; Sanchez-Lopez, Jose; et al.

Ultrasensitive optical detection of hydrogen peroxide by triggered activation of horseradish peroxidase

The Analyst, Royal Society of Chemistry 2010, Vol. 135, (9) : 2291-2295

Virel, Ana; Saa, Laura; Köster, Stephan David; et al.

Characterization of Entamoeba histolytica α-actinin2

Molecular and Biochemical Parasitology, Vol. 154 : 82-89

Virel, Ana; Addario, Barbara; Backman, Lars

A comparative and phylogenetic analysis of the α-Actinin rod domain

Molecular biology and evolution, Oxford University Press 2007, Vol. 24, (10) : 2254-2265

Virel, Ana; Backman, Lars

Characterization of entamoeba histolytica alpha-actinin

Molecular and biochemical parasitology (Print), Amsterdam: Elsevier/North-Holland 2006, Vol. 145, (1) : 11-17

Virel, Ana; Backman, Lars

Molecular Evolution and Structure of α-Actinin

Molecular biology and evolution, Oxford University Press 2004, Vol. 21, (6) : 1024-1031

Virel, Ana; Backman, Lars

View publications in DiVA

Research groups

Head of research

Laboratory of Neurodegeneration and Repair

I teach Histology and Cell Biology within the medical-, biomedicine-, and dentistry program. I am responsible for the histology part of the Morphology course within the dentistry program.

Pedagogical merits

Recognized university teacher 2024