Ulf Lerner

Kontakt

ulf.lerner@umu.se

090-785 62 90

Verksam vid

Anknuten som övrig/annan befattning till Institutionen för odontologi Enhet: Tandläkarutbildningen, Parodontologi

5A, våning 5, Norrlands universitetssjukhus Umeå universitet, 901 85 Umeå

Toll-like receptor-2 induced inflammation causes local bone formation and activates canonical Wnt signaling

Frontiers in Immunology, Frontiers Media S.A. 2024, Vol. 15

Henning, Petra; Kassem, Ali; Westerlund, Anna; et al.

The novel cytotoxic polybisphosphonate osteodex decreases bone resorption by enhancing cell death of mature osteoclasts without affecting osteoclastogenesis of RANKL-stimulated mouse bone marrow macrophages

Investigational new drugs, Springer 2024, Vol. 42, (2) : 207-220

Henning, Petra; Westerlund, Anna; Movérare-Skrtic, Sofia; et al.

The PerioGene North Study uncovers serum proteins related to periodontitis

Journal of Dental Research, Sage Publications 2024, Vol. 103, (10) : 999-1007

Wänman, Magnus; Betnér, Staffan; Esberg, Anders; et al.

Mechanical load, sex hormones, and bone modeling

Biological Mechanisms of Tooth Movement, John Wiley & Sons 2021 : 100-116

Windahl, Sara H.; Lerner, Ulf H.

Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D₃ and parathyroid hormone–induced osteoclastogenesis

The FASEB Journal, Federation Amer Soc Exp Biol 2019, Vol. 33, (12) : 14394-14409

Conaway, H. Herschel; Henning, Petra; Lie, Antia; et al.

The critical interplay between bone resorbing and bone forming cells

Journal of Clinical Periodontology, John Wiley & Sons 2019, Vol. 46 : 33-51

Lerner, Ulf H.; Kindstedt, Elin; Lundberg, Pernilla

Activation of Shc1 Allows Oncostatin M to Induce RANKL and Osteoclast Formation More Effectively Than Leukemia Inhibitory Factor

Frontiers in Immunology, Frontiers Media S.A. 2019, Vol. 10

Persson, Emma; Souza, Pedro P. C.; Floriano-Marcelino, Thais; et al.

Activation of Toll-like receptor 2 induces B1 and B2 kinin receptors in human gingival fibroblasts and in mouse gingiva

Scientific Reports, Nature Publishing Group 2019, Vol. 9

Souza, Pedro P. C.; Lundberg, Pernilla; Lundgren, Inger; et al.

Bone remodeling in relation to androgen receptor activity in prostate cancer bone metastases

Cancer Research, American Association for Cancer Research 2018, Vol. 78, (16) : 50-50

Bovinder Ylitalo, Erik; Nordstrand, Annika; Thysell, Elin; et al.

Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor Activity

International Journal of Molecular Sciences, MDPI 2018, Vol. 19, (4)

Nordstrand, Annika; Bovinder Ylitalo, Erik; Thysell, Elin; et al.

Inhibition of the insulin-like growth factor-1 receptor potentiates acute effects of castration in a rat model for prostate cancer growth in bone

Clinical and Experimental Metastasis, Springer 2017, Vol. 34, (3-4) : 261-271

Nordstrand, Annika; Halin Bergström, Sofia; Thysell, Elin; et al.

SNX10 gene mutation leading to osteopetrosis with dysfunctional osteoclasts

Scientific Reports, Nature Publishing Group 2017, Vol. 7

Stattin, Eva-Lena; Henning, Petra; Klar, Joakim; et al.

Inhibition of lipopolysaccharide-induced osteoclast formation and bone resorption in vitro and in vivo by cysteine proteinase inhibitors

Journal of Leukocyte Biology, FEDERATION AMER SOC EXP BIOL 2017, Vol. 101, (5) : 1233-1243

Strålberg, Fredrik; Kassem, Ali; Kasprzykowski, Franciszek; et al.

Activation of dimeric glucocorticoid receptors in osteoclast progenitors potentiates RANKL induced mature osteoclast bone resorbing activity

Bone, Vol. 93 : 43-54

Conaway, H. Herschel; Henning, Petra; Lie, Anita; et al.

Toll-Like Receptor 2 Stimulation of Osteoblasts Mediates Staphylococcus Aureus Induced Bone Resorption and Osteoclastogenesis through Enhanced RANKL

PLOS ONE, Vol. 11, (6)

Kassem, Ali; Lindholm, Catharina; Lerner, Ulf H.

High plasma osteocalcin is associated with low blood haemoglobin in elderly men: the MrOS Sweden Study

Journal of Internal Medicine, Vol. 280, (4) : 398-406

Lewerin, C.; Johansson, H.; Karlsson, M. K.; et al.

Osteoblast differentiation is enhanced by a nano-to-micro hybrid titanium surface created by Yb:YAG laser irradiation

Clinical Oral Investigations, Springer 2016, Vol. 20, (3) : 503-511

Mariscal-Munoz, Eduardo; Costa, Carlos A. S.; Tavares, Hewerson S.; et al.

Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory Cytokines

PLOS ONE, Vol. 10, (8)

Boström, Elisabeth A.; Kindstedt, Elin; Sulniute, Rima; et al.

A new WNT on the bone: WNT16, cortical bone thickness, porosity and fractures

BoneKEy Reports, Vol. 4

Gori, Francesca; Lerner, Ulf; Ohlsson, Claes; et al.

Retinoid receptors in bone and their in bone remodeling

Frontiers in Endocrinology, Vol. 6

Henning, Petra; Conaway, H. Herschel; Lerner, Ulf H.

TLR5, a novel mediator of innate immunity-induced osteoclastogenesis and bone loss

The FASEB Journal, Vol. 29, (11) : 4449-4460

Kassem, Ali; Henning, Petra; Kindlund, Bert; et al.

Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-kappa B Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts

Journal of Biological Chemistry, Vol. 290, (33) : 20147-20158

Kassem, Ali; Henning, Petra; Lundberg, Pernilla; et al.

The WNT system: background and its role in bone

Journal of Internal Medicine, Wiley-Blackwell 2015, Vol. 277, (6) : 630-649

Lerner, Ulf H; Ohlsson, C

High serum adiponectin is associated with low blood haemoglobin in elderly men: the Swedish MrOS study

Journal of Internal Medicine, Vol. 278, (1) : 68-76

Lewerin, C.; Johansson, H.; Lerner, Ulf H.; et al.

Mechanical load, sex hormones, and bone modeling

Biological mechanisms of tooth movement, Wiley Blackwell 2015 : 82-96

Windahl, Sara H.; Lerner, Ulf H.

Low holotranscobalamin and cobalamins predict incident fractures in elderly men: the MrOS Sweden

Osteoporosis International, Springer London 2014, Vol. 25, (1) : 131-140

Lewerin, C.; Nilsson-Ehle, H.; Jacobsson, S.; et al.

Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

Nature Medicine, Nature Publishing Group 2014, Vol. 20, (11) : 1279-1288

Movérare-Skrtic, Sofia; Henning, Petra; Liu, Xianwen; et al.

Vitamin A metabolism, action, and role in skeletal homeostasis

Endocrine reviews, The Endocrine Society 2013, Vol. 34, (6) : 766-797

Conaway, H. Herschel; Henning, Petra; Lerner, Ulf H.

Low-dose prednisolone in early rheumatoid arthritis inhibits collagen type I degradation by matrix metalloproteinases as assessed by serum 1CTP--a possible mechanism for specific inhibition of radiological destruction

Rheumatology, Vol. 52, (4) : 733-742

Engvall, Inga-Lill; Svensson, Björn; Boonen, Annelies; et al.

Osteoclast progenitor cells present in significant amounts in mouse calvarial osteoblast isolations and osteoclastogenesis increased by BMP-2

Bone, Vol. 52, (1) : 83-92

Granholm, Susanne; Henning, Petra; Lindholm, Catharina; et al.

Inhibition of the insulin-like growth factor-1 receptor enhances effects of Simvastatin on prostate cancer cells in co-culture with bone

Cancer Microenvironment, Springer 2013, Vol. 6, (3) : 231-240

Nordstrand, Annika; Lundholm, Marie; Larsson, Andreas; et al.

Activation of the liver X receptor-beta potently inhibits osteoclastogenesis from lipopolysaccharide-exposed bone marrow-derived macrophages

Journal of Leukocyte Biology, Vol. 93, (1) : 71-82

Remen, Kirsten M. Robertson; Lerner, Ulf H.; Gustafsson, Jan-Åke; et al.

Activation of the liver X receptor-β potently inhibits osteoclastogenesis from lipopolysaccharide-exposed bone marrowderived macrophages

Journal of Leukocyte Biology, Vol. 93, (1) : 71-82

Robertson Remen, K. M.; Lerner, Ulf H.; Gustafsson, J.; et al.

IL-4 and IL-13 inhibit IL-1 beta and TNF-alpha induced kinin B-1 and B-2 receptors through a STAT6-dependent mechanism

British Journal of Pharmacology, Vol. 169, (2) : 400-412

Souza, P. P. C.; Brechter, A. B.; Reis, R. I.; et al.

The role of cytokines in inflammatory bone loss

Immunological Investigations, Vol. 42, (7) : 555-622

Souza, Pedro P. C.; Lerner, Ulf H.

Cysteine proteinase inhibitors regulate human and mouse osteoclastogenesis by interfering with RANK signaling

The FASEB Journal, Vol. 27, (7) : 2687-2701

Strålberg, Fredrik; Henning, Petra; Gjertsson, Inger; et al.

Estrogen Receptor-alpha is required for the Osteogenic Response to mechanical loading in a Ligand-Independent manner involving its activation function 1 but Not 2

Journal of Bone and Mineral Research, Vol. 28, (2) : 291-301

Windahl, Sara H.; Saxon, Leanne; Borjesson, Anna E.; et al.

Inhibition of osteoclast formation in human peripheral CD14+cells by vitamin A

Bone, Vol. 50, (Supplement 1) : S92-S92

Henning, P.; Kindlund, B.; Pettersson, Ulrika; et al.

Interleukin 15 mediates joint destruction in staphylococcus aureus arthritis

Journal of Infectious Diseases, Vol. 206, (5) : 687-696

Henningsson, Louise; Jirholt, Pernilla; Bogestal, Yalda Rahpeymai; et al.

High serum adiponectin predicts incident fractures in elderly men: mr os sweden

Osteoporosis International, Vol. 23, (Suppl 2) : S306-S307

Johansson, H.; Oden, A.; Lerner, Ulf H.; et al.

High serum adiponectin predicts incident fractures in elderly men: osteoporotic fractures in men (MrOS) Sweden

Journal of Bone and Mineral Research, Vol. 27, (6) : 1390-1396

Johansson, Helena; Oden, Anders; Lerner, Ulf H; et al.

Regulation of osteoclast formation by toll-like receptors 2 and 5

Bone, Vol. 50, (Supplement 1) : S67-S67

Kassem, Ali; Lunberg, Pernilla; Lindholm, C.; et al.

Regulation of osteoclast formation by toll-like receptors 2 and 5

Bone, Vol. 50, (Supplement 1) : S86-S87

Kassem, Ali; Lunberg, Pernilla; Lindholm, C.; et al.

Stimulation of bone resorption in calvarial bones by toll-like2 receptor through enhanced rankl

Annals of the Rheumatic Diseases, Vol. 71 : A68-A68

Kassem, Ali; Souza, Pedro C. C.; Lundberg, Pernilla; et al.

Endokrin reglering av benförlust och benregeneration

BestPractice Reumatologi, (13) : 14-18

Lerner, Ulf

Skelettet i käkar och annorstädes: 4. Skelettet som ett hormonproducerande organ med betydelse för energimetabolism och fosfatutsöndring

Tandläkartidningen, Vol. 104, (8) : 60-68

Lerner, Ulf H

The biology of bone remodelling in jaw bones with and without teeth

Textbook of removable prosthodontics: the Scandinavian approach, Munksgaard Forlag 2012 : 51-60

Lerner, Ulf H

Osteoblasts, Osteoclasts, and Osteocytes: Unveiling Their Intimate-Associated Responses to Applied Orthodontic Forces

Seminars in orthodontics, Elsevier 2012, Vol. 18, (4) : 237-248

Lerner, Ulf H

Behandlingsprinciper för olika läkemedel vid osteoporos: skelettet i käkar och annorstädes, del 5

Tandläkartidningen, Vol. 104, (11) : 64-79

Lerner, Ulf H; Mellström, Dan

The gut microbiota regulates bone mass in mice

Journal of Bone and Mineral Research, Vol. 27, (6) : 1357-1367

Sjögren, Klara; Engdahl, Cecilia; Henning, Petra; et al.

Visa publikationer i DiVA

Forskningsprojekt

3 december 2007 till 31 december 2007

Nedbrytning och uppbyggnad av benvävnad