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Umeå universitet
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Personalbild Thomas Brännström
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Thomas Brännström

Vetenskaplig meritering: Docent

Kontakt

E-post
thomas.brannstrom@umu.se
Telefon
090-785 15 23

Verksam vid

Anknytning
Professor, överläkare vid Institutionen för medicinsk biovetenskap Enhet: Patologi Roll: Avdelningschef
Plats
By 6M, vån , Sjukhusområdet Umeå universitet, 901 85 Umeå
Myofiber type shift in extraocular muscles in amyotrophic lateral sclerosis
Investigative Ophthalmology and Visual Science, Association for Research in Vision and Ophthalmology (ARVO) 2023, Vol. 64, (5)
Behzadi, Arvin; Tjust, Anton Erik; Liu, Jing-Xia; et al.
Widespread CNS pathology in amyotrophic lateral sclerosis homozygous for the D90A SOD1 mutation
Acta Neuropathologica, Springer-Verlag New York 2023, Vol. 145, (1) : 13-28
Forsberg, Karin; Graffmo, Karin Sixtensdotter; Stenvall, Erica; et al.
Distinct metabolic hallmarks of WHO classified adult glioma subtypes
Neuro-Oncology, Oxford University Press 2022, Vol. 24, (9) : 1454-1468
Björkblom, Benny; Wibom, Carl; Eriksson, Maria; et al.
Respiratory onset of amyotrophic lateral sclerosis in a pregnant woman with a novel SOD1 mutation
European Journal of Neurology, John Wiley & Sons 2022, Vol. 29, (4) : 1279-1283
Masrori, Pegah; Ospitalieri, Simona; Forsberg, Karin; et al.
Peripheral administration of SOD1 aggregates does not transmit pathogenic aggregation to the CNS of SOD1 transgenic mice
Acta neuropathologica communications, BioMed Central 2021, Vol. 9, (1)
Keskin, Isil; Ekhtiari Bidhendi, Elaheh; Marklund, Matthew; et al.
Aggregate-selective antibody attenuates seeded aggregation but not spontaneously evolving disease in SOD1 ALS model mice
Acta neuropathologica communications, BMC 2020, Vol. 8, (1)
Lehmann, Manuela; Marklund, Matthew; Bolender, Anna-Lena; et al.
Mutant SOD1 aggregates from human ventral horn transmit templated aggregation and fatal ALS-like disease
Brain Pathology, John Wiley & Sons 2019, Vol. 29 : 90-90
Brännström, Thomas; Andersen, Peter M.; Bergh, Johan; et al.
Misfolded SOD1 inclusions in patients with mutations in C9orf72 and other ALS/FTD-associated genes
Journal of Neurology, Neurosurgery and Psychiatry, BMJ Publishing Group Ltd 2019, Vol. 90, (8) : 861-869
Forsberg, Karin; Graffmo, Karin Sixtensdotter; Pakkenberg, Bente; et al.
The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension
Acta Neuropathologica, New York: Springer 2019, Vol. 138, (1) : 85-101
Keskin, Isil; Forsgren, Elin; Lehmann, Manuela; et al.
The Genetic Architecture of Gliomagenesis-Genetic Risk Variants Linked to Specific Molecular Subtypes
Cancers, MDPI 2019, Vol. 11, (12)
Wu, Wendy Yi-Ying; Johansson, Gunnar; Wibom, Carl; et al.
Mutant superoxide dismutase aggregates from human spinal cord transmit amyotrophic lateral sclerosis
Acta Neuropathologica, Springer 2018, Vol. 136, (6) : 939-953
Ekhtiari Bidhendi, Elaheh; Bergh, Johan; Zetterström, Per; et al.
Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis
Scientific Reports, Nature Publishing Group 2018, Vol. 8
Paré, Bastien; Lehmann, Manuela; Beaudin, Marie; et al.
Telomere length, allergies and risk of Glioma
Neuro-Oncology, Oxford University Press 2017, Vol. 19, (S3) : 23-23
Andersson, Ulrika; Degerman, Sofie; Dahlin, Anna; et al.
Molecular classification of malignat glioma
Neuro-Oncology, Oxford University Press 2017, Vol. 19, (S3) : 88-88
Johansson, Gunnar; Brännström, Thomas; Andersson, Ulrika; et al.
Sequence variations in C9orf72 downstream of the hexanucleotide repeat region and its effect on repeat-primed PCR interpretation: a large multinational screening study
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Vol. 18, (3-4) : 256-264
Nordin, Angelica; Akimoto, Chizuru; Wuolikainen, Anna; et al.
Radiotherapy induces an immediate inflammatory reaction in malignant glioma: a clinical microdialysis study
Journal of Neuro-Oncology, Springer 2017, Vol. 131, (1) : 83-92
Tabatabaei, Pedram; Visse, Eward; Bergström, Per; et al.
Impact of Amyotrophic Lateral Sclerosis on Slow Tonic Myofiber Composition in Human Extraocular Muscles
Investigative Ophthalmology and Visual Science, ASSOC RESEARCH VISION OPHTHALMOLOGY INC 2017, Vol. 58, (9) : 3708-3715
Tjust, Anton E.; Danielsson, Adam; Andersen, Peter M.; et al.
The Glioma International Case-Control Study: A Report From the Genetic Epidemiology of Glioma International Consortium
American Journal of Epidemiology, Vol. 183, (2) : 85-91
Amirian, E. Susan; Armstrong, Georgina N.; Zhou, Renke; et al.
Relation between Established Glioma Risk Variants and DNA Methylation in the Tumor
PLOS ONE, Public library science 2016, Vol. 11, (10)
Dahlin, Anna M.; Wibom, Carl; Ghasimi, Soma; et al.
Two superoxide dismutase prion strains transmit amyotrophic lateral sclerosis-like disease
Journal of Clinical Investigation, Vol. 126, (6) : 2249-2253
Ekhtiari Bidhendi, Elaheh; Bergh, Johan; Zetterström, Per; et al.
Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma
Journal of Neuro-Oncology, Vol. 127, (3) : 483-492
Ghasimi, Soma; Wibom, Carl; Dahlin, Anna M.; et al.
Unchanged neurotrophic factors and their receptors correlate with sparing in extraocular muscles in amyotrophic lateral sclerosis
Investigative Ophthalmology and Visual Science, Rockville: The association for research in vision and ophthalmology 2016, Vol. 57, (15) : 6831-6842
Harandi, Vahid M; Gaied, Aida RN; Brännström, Thomas; et al.
Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase
Acta neuropathologica communications, Vol. 4
Tokuda, Eiichi; Brännström, Thomas; Andersen, Peter M.; et al.
Structural and kinetic analysis of protein-aggregate strains in vivo using binary epitope mapping
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 2015, Vol. 112, (14) : 4489-4494
Bergh, Johan; Zetterström, Per; Andersen, Peter M.; et al.
Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
Nature Neuroscience, Vol. 18, (5) : 631-+
Freischmidt, Axel; Wieland, Thomas; Richter, Benjamin; et al.
SOD1 aggregation in ALS mice shows simplistic test tube behavior
Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, (32) : 9878-9883
Lang, Lisa; Zetterström, Per; Brännström, Thomas; et al.
Metabolomic screening of tumor tissue and serum in glioma patients reveals diagnostic and prognostic information
Metabolites, MDPI 2015, Vol. 5, (3) : 502-520
Mörén, Lina; Bergenheim, A Tommy; Ghasimi, Soma; et al.
Extensive size variability of the GGGGCC expansion in C9orf72 in both neuronal and non-neuronal tissues in 18 patients with ALS or FTD
Human Molecular Genetics, Vol. 24, (11) : 3133-3142
Nordin, Angelica; Akimoto, Chizuru; Wuolikainen, Anna; et al.
Targeting glucosylceramide synthase induction of cell surface globotriaosylceramide (Gb3) in acquired cisplatin-resistance of lung cancer and malignant pleural mesothelioma cells
Experimental Cell Research, Vol. 336, (1) : 23-32
Tyler, Andreas; Johansson, Anders; Karlsson, Terese; et al.
A Generic Method for Design of Oligomer-Specific Antibodies
PLOS ONE, Vol. 9, (3) : e90857-
Brännström, Kristoffer; Lindhagen-Persson, Malin; Gharibyan, Anna L.; et al.
Induction of ubiquilin differs between different SOD1 transgenic strains
Neuropathology and Applied Neurobiology, Vol. 40, (S1) : 22-22
Brännström, Thomas; Sirkka, S.
Wnt and Extraocular Muscle Sparing in Amyotrophic Lateral Sclerosis
Investigative Ophthalmology and Visual Science, ARVO, The Association for Reserach in Vision and Ophthalmology 2014, Vol. 55, (9) : 5482-5496
McLoon, Linda K; Harandi, Vahid M; Brännstrom, Thomas; et al.
Analysis of Neurotrophic Factors in Limb and Extraocular Muscles of Mouse Model of Amyotrophic Lateral Sclerosis
PLOS ONE, Vol. 9, (10)
Vahid, Harandi M.; Susanne, Lindquist; Shrikant, Shantilal Kolan; et al.
The role of pro-inflammatory S100A9 in Alzheimer's disease amyloid-neuroinflammatory cascade
Acta Neuropathologica, Vol. 127, (4) : 507-522
Wang, Chao; Klechikov, Alexey G.; Gharibyan, Anna L.; et al.
Expression of wild-type human superoxide dismutase-1 in mice causes amyotrophic lateral sclerosis
Human Molecular Genetics, Vol. 22, (1) : 51-60
Graffmo, Karin S.; Forsberg, Karin; Bergh, Johan; et al.
Distinct changes in synaptic protein composition at neuromuscular junctions of extraocular muscles versus limb muscles of ALS donors
PLOS ONE, Vol. 8, (2) : e57473-
Liu, Jing-Xia; Brännström, Thomas; Andersen, Peter M; et al.
Fatal neuroinflammation in a case of multiple sclerosis with anti-natalizumab antibodies
Neurology, Vol. 80, (10) : 965-967
Svenningsson, Anders; Dring, Ann Marie; Fogdell-Hahn, Anna; et al.
Composition of soluble misfolded superoxide Dismutase-1 in murine models of Amyotrophic Lateral Sclerosis
Neuromolecular medicine, Vol. 15, (1) : 147-158
Zetterström, Per; Graffmo, Karin S.; Andersen, Peter M; et al.
Cisplatin Resistance in Malignant Pleural Mesothelioma
Mesotheliomas: Synonyms and Definition, Epidemiology, Etiology, Pathogenesis, Cyto-Histopathological Features, Clinic, Diagnosis, Treatment, Prognosis, Zagreb: InTech 2012 : 169-186
Behnam-Mothlag, Parviz; Tyler, Andreas; Brännström, Thomas; et al.
Immunohistochemical analysis of LRIG proteins in meningiomas: correlation between estrogen receptor status and LRIG expression
Neuro-Oncology, Oxford University Press 2012, Vol. 14, (Suppl 3) : 69-69
Ghasimi, Soma; Haapasalo, H.; Eray, M.; et al.
Immunohistochemical analysis of LRIG proteins in meningiomas: correlation between estrogen receptor status and LRIG expression
Journal of Neuro-Oncology, Vol. 108, (3) : 435-441
Ghasimi, Soma; Haapasalo, Hannu; Eray, Mine; et al.
Radioligand binding to brain dopamine and serotonin receptors and transporters in Parkinson's disease: relation to gene polymorphisms
International Journal of Neuroscience, New York: Gordon and Breach 2012, Vol. 122, (3) : 124-132
Güzey, Cüneyt; Allard, Per; Brännström, Thomas; et al.
EGFR expression and glioblastoma outcome
Neuro-Oncology, Oxford: Oxford University Press 2012, Vol. 14, (Suppl. 3) : 19-19
Sjöström, Sara; Ghasimi, Soma; Broholm, H.; et al.
Microbubbles of air may occur in the organs of hemodialysis patients
ASAIO journal (1992), Vol. 58, (2) : 177-179
Stegmayr, Bernd; Brännström, Thomas; Forsberg, Ulf; et al.
Unaffected motor endplate occupancy in eye muscles of ALS G93A mouse model
Frontiers in bioscience (Scholar edition), Frontiers in Bioscience 2012, Vol. 4 : 1547-1555
Tjust, Anton E; Brännstrom, Thomas; Pedrosa Domellöf, Fatima
EGFR gene variants are associated with specific somatic aberrations in glioma
Neuro-Oncology, Vol. 14, (Suppl. 3) : 46-46
Wibom, Carl; Ghasimi, Soma; Van Loo, P.; et al.
EGFR gene variants are associated with specific somatic aberrations in glioma
PLOS ONE, plosone.org 2012, Vol. 7, (12) : e47929-
Wibom, Carl; Ghasimi, Soma; Van Loo, Peter; et al.
DNA-repair gene variants are associated with glioblastoma survival
Acta Oncologica, Informa Healthcare 2012, Vol. 51, (3) : 325-332
Wibom, Carl; Sjöström, Sara; Henriksson, Roger; et al.
Co-expression of Globotriasosylceramide (Gb3) With MDR1 in Cisplatin-resistant Pleural Mesothelioma and Non-small Cell Lung Cancer Cell May Lead to a New Tumour Resistance Treatment Approach
European Journal of Cancer, Vol. 47 Suppl. 1
Behnam Motlagh, Parviz; Tyler, Andreas; Johansson, Anders; et al.
Analysis of DNA repair gene polymorphisms and survival in low-grade and anaplastic gliomas
Journal of Neuro-Oncology, Vol. 105, (3) : 531-538
Berntsson, Shala Ghaderi; Wibom, Carl; Sjöström, Sara; et al.
Visa publikationer i DiVA

Forskargrupper

Forskningsledare
ALS-forskning Umeå
Styrgrupp
StratNeuro
Forskningsledare
Thomas Brännströms labb
Gruppmedlem
Medical Humanities Network
Thomas Brännström: Klumpar av protein en orsak till ALS

Klumpar av protein i nervcellerna finns hos alla patienter med ALS.