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Umeå universitet
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Huvudmenyn dold.
Personalbild Sara Pudas

Sara Pudas

Jag forskar om kognitivt och neuralt åldrande.

Vetenskaplig meritering: Docent

Kontakt

E-post
sara.pudas@umu.se
Telefon
090-786 52 29

Verksam vid

Anknytning
Forskare vid Institutionen för medicinsk och translationell biologi Enhet: Grupp Lars Nyberg
Plats
hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå
Anknytning
Universitetslektor vid Institutionen för psykologi
Plats
Hus Y, Beteendevetarhuset, Vindarnas torg, Mediagränd 14, C-216 Umeå universitet, 901 87 Umeå
Anknytning
Anknuten som övrig/annan befattning till Umeå centrum för funktionell hjärnavbildning (UFBI) Roll: Biträdande föreståndare
Plats
Biologihuset, Avdelningen för fysiologi Umeå universitet, 90187 Umeå

Min forskning undersöker orsaker till individuella skillnader i kognitivt åldrande, framförallt i vår minnesförmåga. Med andra ord: varför behåller vissa personer en god minnesförmåga upp i hög ålder, medan andra successivt förlorar den? För att bättre förstå dessa skillnader studerar jag hjärnans struktur och funktion, biologiska markörer, skillnader i livsstil och levnadsförutsättningar, samt kognitiv förmåga tidigt i livet. Min forskning bedrivs främst inom ramen för det longitudinella Betulaprojektet, men jag medverkar också i ett europeiskt konsortium, Lifebrain, för att studera dessa frågor. Jag är även knuten till Umeå center för funktionell hjärnavbildning, UFBI.

Explaining graph convolutional network predictions for clinicians: an explainable AI approach to Alzheimer’s disease classification
Frontiers in Artificial Intelligence, Frontiers Media S.A. 2024, Vol. 6
Anjomshoae, Sule; Pudas, Sara
Revised temperament and character inventory factors predict neuropsychiatric symptoms and aging-related cognitive decline across 25 years
Frontiers in Aging Neuroscience, Frontiers Media S.A. 2024, Vol. 16
Ronat, Lucas; Rönnlund, Michael; Adolfsson, Rolf; et al.
A Bayesian semiparametric approach for inference on the population partly conditional mean from longitudinal data with dropout
Biostatistics, Oxford University Press 2023, Vol. 24, (2) : 372-387
Josefsson, Maria; Daniels, Michael J.; Pudas, Sara
Memory profiles predict dementia over 23–28 years in normal but not successful aging
International psychogeriatrics, Cambridge University Press 2023, Vol. 35, (7) : 351-359
Josefsson, Maria; Sundström, Anna; Pudas, Sara; et al.
Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates
Cerebral Cortex, Oxford University Press 2023, Vol. 33, (9) : 5075-5081
Nyberg, Lars; Andersson, Micael; Lundquist, Anders; et al.
Sixteen-year longitudinal evaluation of blood-based DNA methylation biomarkers for early prediction of Alzheimer’s disease
Journal of Alzheimer's Disease, IOS Press 2023, Vol. 94, (4) : 1443-1464
Schäfer Hackenhaar, Fernanda; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
Healthy Middle-Aged Adults Have Preserved Mnemonic Discrimination and Integration, While Showing No Detectable Memory Benefits
Frontiers in Psychology, Frontiers Media S.A. 2022, Vol. 12
Samrani, George; Lundquist, Anders; Pudas, Sara
No Association Between Loneliness, Episodic Memory and Hippocampal Volume Change in Young and Healthy Older Adults: A Longitudinal European Multicenter Study
Frontiers in Aging Neuroscience, Frontiers Media S.A. 2022, Vol. 14
Solé-Padullés, Cristina; Macià, Dídac; Andersson, Micael; et al.
Education and Income Show Heterogeneous Relationships to Lifespan Brain and Cognitive Differences Across European and US Cohorts
Cerebral Cortex, Oxford University Press 2022, Vol. 32, (4) : 839-854
Walhovd, Kristine B.; Fjell, Anders M.; Wang, Yunpeng; et al.
Poor Self-Reported Sleep is Related to Regional Cortical Thinning in Aging but not Memory Decline-Results From the Lifebrain Consortium
Cerebral Cortex, Oxford University Press 2021, Vol. 31, (4) : 1953-1969
Fjell, Anders M.; Sørensen, Øystein; Amlien, Inge K.; et al.
Self-reported sleep relates to microstructural hippocampal decline in beta-amyloid positive Adults beyond genetic risk
Sleep, Oxford University Press 2021, Vol. 44, (11)
Grydeland, Håkon; Sederevicius, Donatas; Wang, Yunpeng; et al.
Sex-specific effects of polygenic risk for schizophrenia on lifespan cognitive functioning in healthy individuals
Translational Psychiatry, Springer Nature 2021, Vol. 11, (1)
Koch, Elise; Nyberg, Lars; Lundquist, Anders; et al.
Educational attainment does not influence brain aging
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, (18)
Nyberg, Lars; Magnussen, Fredrik; Lundquist, Anders; et al.
Short leukocyte telomeres, but not telomere attrition rates, predict memory decline in the 20-year longitudinal Betula study
The journals of gerontology. Series A, Biological sciences and medical sciences, Oxford University Press 2021, Vol. 76, (6) : 955-963
Pudas, Sara; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease
Nature Communications, Nature Research 2021, Vol. 12, (1)
Roe, James M.; Vidal-Piñeiro, Didac; Sørensen, Øystein; et al.
Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-APOE ε4-carriers
Alzheimer's Research & Therapy, BioMed Central (BMC) 2021, Vol. 13
Schäfer Hackenhaar, Fernanda; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
Self-reported sleep relates to hippocampal atrophy across the adult lifespan: results from the Lifebrain consortium
Sleep, Oxford University Press 2020, Vol. 43, (5)
Fjell, Anders M.; Sørensen, Øystein; Amlien, Inge K.; et al.
Longitudinal association between hippocampus atrophy and episodic-memory decline in non-demented APOE ε4 carriers
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, John Wiley & Sons 2020, Vol. 12, (1)
Gorbach, Tetiana; Pudas, Sara; Bartrés-Faz, David; et al.
Effects of polygenic risk for Alzheimer's disease on rate of cognitive decline in normal aging
Translational Psychiatry, Nature Publishing Group 2020, Vol. 10, (1)
Kauppi, Karolina; Rönnlund, Michael; Nordin Adolfsson, Annelie; et al.
Biological and environmental predictors of heterogeneity in neurocognitive ageing: Evidence from Betula and other longitudinal studies
Ageing Research Reviews, Elsevier 2020, Vol. 64
Nyberg, Lars; Boraxbekk, Carl-Johan; Eriksson Sörman, Daniel; et al.
Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
Molecular Psychiatry, Nature Publishing Group 2020, Vol. 25, (3) : 584-602
Sonderby, Ida E.; Gustafsson, Omar; Doan, Nhat Trung; et al.
Successful Memory Aging
Annual Review of Psychology, Vol. 70 : 219-243
Nyberg, Lars; Pudas, Sara
School Performance and Educational Attainment as Early-Life Predictors of Age-Related Memory Decline: Protective Influences in Later-Born Cohorts
The journals of gerontology. Series B, Psychological sciences and social sciences, Oxford University Press 2019, Vol. 74, (8) : 1356-1365
Pudas, Sara; Rönnlund, Michael
Longitudinal evidence for increased functional response in frontal cortex for older adults with hippocampal atrophy and memory decline
Cerebral Cortex, Oxford University Press 2018, Vol. 28, (3) : 936-948
Pudas, Sara; Josefsson, Maria; Rieckmann, Anna; et al.
Maintained memory in aging is associated with young epigenetic age
Neurobiology of Aging, Elsevier 2017, Vol. 55 : 167-171
Degerman, Sofie; Josefsson, Maria; Nordin Adolfsson, Annelie; et al.
Longitudinal association between hippocampus atrophy and episodic-memory decline
Neurobiology of Aging, Vol. 51 : 167-176
Gorbach, Tetiana; Pudas, Sara; Lundquist, Anders; et al.
Structural and functional imaging of aging: longitudinal sudies
Cognitive neuroscience of aging: linking cognitive and cerebral aging, New York: Oxford University Press 2017 : 155-182
Nyberg, Lars; Pudas, Sara; Lundquist, Anders
Longitudinal Changes in Component Processes of Working Memory
eNeuro, Vol. 4, (2)
Rieckmann, Anna; Pudas, Sara; Nyberg, Lars
Midlife level and 15-year changes in general cognitive ability in a sample of men: the role of education, early adult ability, BMI, and pulse pressure
Intelligence, Elsevier 2017, Vol. 61 : 78-84
Rönnlund, Michael; Sundström, Anna; Pudas, Sara
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Nature Neuroscience, Vol. 19, (12) : 1569-1582
Adams, Hieab H. H.; Hibar, Derrek P.; Chouraki, Vincent; et al.
Aging of memory and brain functions: usual and successful
From Neuroscience to Neurospyschology: the study of the human brain. Volume II, Bogotá, Colombia: Ediciones Corporación Universitaria Reformada 2016 : 163-192
Pudas, Sara
Age-related and genetic modulation of frontal cortex efficiency
Journal of cognitive neuroscience, Vol. 26, (4) : 746-754
Nyberg, Lars; Andersson, Micael; Kauppi, Karolina; et al.
Longitudinal assessment of default-mode brain function in aging
Neurobiology of Aging, Elsevier 2014, Vol. 35, (9) : 2107-2117
Persson, Jonas; Pudas, Sara; Nilsson, Lars-Göran; et al.
Midlife memory ability accounts for brain activity differences in healthy aging
Neurobiology of Aging, Elsevier 2014, Vol. 35, (11) : 2495-2503
Pudas, Sara; Persson, Jonas; Nilsson, Lars-Göran; et al.
Elevated hippocampal resting-state connectivity underlies deficient neurocognitive function in aging
Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, (49) : 17654-17659
Salami, Alireza; Pudas, Sara; Nyberg, Lars
Brain Characteristics of Individuals Resisting Age-Related Cognitive Decline over Two Decades
Journal of Neuroscience, Vol. 33, (20) : 8668-8677
Pudas, Sara; Persson, Jonas; Josefsson, Maria; et al.
Genetic and lifestyle predictors of 15-Year longitudinal change in episodic memory
Journal of The American Geriatrics Society, Vol. 60, (12) : 2308-2312
Josefsson, Maria; de Luna, Xavier; Pudas, Sara; et al.
Longitudinal structure-function correlates in elderly reveal MTL dysfunction with cognitive decline
Cerebral Cortex, New York, NY: Oxford University Press 2012, Vol. 22, (10) : 2297-2304
Persson, Jonas; Pudas, Sara; Lind, Johanna; et al.
Longitudinal evidence for diminished frontal cortex function in aging
Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, (52) : 22682-22686
Nyberg, Lars; Salami, Alireza; Andersson, Mikael; et al.
Maintenance and Manipulation in Working Memory: Differential Ventral and Dorsal Frontal Cortex fMRI Activity
Acta Psychologica Sinica, Vol. 41, (11) : 1054-1062
Pudas, Sara; Persson, Jonas; Nilsson, Lars-Göran; et al.
Visa publikationer i DiVA

Jag undervisar i flera olika delområden inom kognitiv neurovetenskap, kognitionsvetenskap och psykologi. Därutöver handleder jag även studentprojekt och uppsatser.