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Pär Jonsson
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par.jonsson@umu.se
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Kemiska institutionen
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KB.A4, Linnaeus väg 10
Umeå universitet, 901 87 Umeå
Publikationer
Publikationer
Forskning
Forskning
2024
Metabolomics for early pancreatic cancer detection in plasma samples from a Swedish prospective population-based biobank
Journal of Gastrointestinal Oncology
, AME Publishing Company 2024, Vol. 15, (2) : 755-767
Borgmästars, Emmy; Jacobson, Sara; Simm, Maja; et al.
2024
Multi-omics profiling to identify early plasma biomarkers in pre-diagnostic pancreatic ductal adenocarcinoma: a nested case-control study
Translational Oncology
, Elsevier 2024, Vol. 48
Borgmästars, Emmy; Ulfenborg, Benjamin; Johansson, Mattias; et al.
2024
A scalable, data analytics workflow for image-based morphological profiles
Chemometrics and Intelligent Laboratory Systems
, Elsevier 2024, Vol. 254
Forsgren, Edvin; Cloarec, Olivier; Jonsson, Pär; et al.
2024
Peritoneal infection after colorectal cancer surgery induces substantial alterations in postoperative protein levels: an exploratory study
Langenbeck's archives of surgery (Print)
, Springer Nature 2024, Vol. 409
Grahn, Oskar; Holmgren, Klas; Jonsson, Pär; et al.
2022
Distinct metabolic hallmarks of WHO classified adult glioma subtypes
Neuro-Oncology
, Oxford University Press 2022, Vol. 24, (9) : 1454-1468
Björkblom, Benny; Wibom, Carl; Eriksson, Maria; et al.
2022
Preoperative biomarkers related to inflammation may identify high-risk anastomoses in colorectal cancer surgery: explorative study
BJS Open
, Oxford University Press 2022, Vol. 6, (3)
Holmgren, Klas; Jonsson, Pär; Lundin, Christina; et al.
2022
Type IV Collagen in Human Colorectal Liver Metastases—Cellular Origin and a Circulating Biomarker
Cancers
, MDPI 2022, Vol. 14, (14)
Lindgren, Moa; Rask, Gunilla; Jonsson, Josefin; et al.
2022
A cross-sectional and longitudinal analysis of pre-diagnostic blood plasma biomarkers for early detection of pancreatic cancer
International Journal of Molecular Sciences
, MDPI 2022, Vol. 23, (21)
Mason, James E.; Lundberg, Erik; Jonsson, Pär; et al.
2021
Circulating tissue polypeptide-specific antigen in pre-diagnostic pancreatic cancer samples
Cancers
, MDPI 2021, Vol. 13, (21)
Borgmästars, Emmy; Lundberg, Erik; Öhlund, Daniel; et al.
2020
Metabolic response patterns in brain microdialysis fluids and serum during interstitial cisplatin treatment of high-grade glioma
British Journal of Cancer
, Nature Publishing Group 2020, Vol. 122, (2) : 221-232
Björkblom, Benny; Jonsson, Pär; Tabatabaei, Pedram; et al.
2020
Identification of Pre-Diagnostic Metabolic Patterns for Glioma Using Subset Analysis of Matched Repeated Time Points
Cancers
, MDPI 2020, Vol. 12, (11)
Jonsson, Pär; Antti, Henrik; Späth, Florentin; et al.
2018
Pre-diagnostic plasma metabolites linked to future brain tumor development
Neuro-Oncology
, Oxford University Press 2018, Vol. 20 : 288-289
Björkblom, Benny; Jonsson, Pär; Späth, Florentin; et al.
2018
Plasma micro-RNA alterations appear late in pancreatic cancer
Annals of Surgery
, Vol. 267, (4) : 775-781
Franklin, Oskar; Jonsson, Pär; Billing, Ola; et al.
2018
Diagnostic metabolite biomarkers of chronic typhoid carriage
PLoS Neglected Tropical Diseases
, Vol. 12, (1)
Näsström, Elin; Jonsson, Pär; Johansson, Anders; et al.
2016
Metabolomic screening of pre-diagnostic serum samples identifies association between alpha- and gamma-tocopherols and glioblastoma risk
Oncotarget
, Vol. 7, (24) : 37043-37053
Björkblom, Benny; Wibom, Carl; Jonsson, Pär; et al.
2016
NMR analysis of the human saliva metabolome distinguishes dementia patients from matched controls
Molecular Biosystems
, Vol. 12, (8) : 2562-2571
Figueira, Joao; Jonsson, Pär; Nordin Adolfsson, Annelie; et al.
2016
NMR analysis of the CSF and plasma metabolome of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects
Metabolomics
, Vol. 12, (6)
Wu, Junfang; Wuolikainen, Anna; Trupp, Miles; et al.
2016
Multi-platform mass spectrometry analysis of the CSF and plasma metabolomes of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects
Molecular Biosystems
, Vol. 12, (4) : 1287-1298
Wuolikainen, Anna; Jonsson, Pär; Ahnlund, Maria; et al.
2015
Constrained randomization and multivariate effect projections improve information extraction and biomarker pattern discovery in metabolomics studies involving dependent samples
Metabolomics
, Springer 2015, Vol. 11, (6) : 1667-1678
Jonsson, Pär; Wuolikainen, Anna; Thysell, Elin; et al.
2015
Extensive size variability of the GGGGCC expansion in C9orf72 in both neuronal and non-neuronal tissues in 18 patients with ALS or FTD
Human Molecular Genetics
, Vol. 24, (11) : 3133-3142
Nordin, Angelica; Akimoto, Chizuru; Wuolikainen, Anna; et al.
2014
Serum metabolomic biomarkers of dementia
Dementia and Geriatric Cognitive Disorders Extra
, Vol. 4, (2) : 252-62
Mousavi, Malahat; Jonsson, Pär; Antti, Henrik; et al.
2014
Metabolite and peptide levels in plasma and CSF differentiating healthy controls from patients with newly diagnosed Parkinson's disease
Journal of Parkinson's Disease
, Taylor & Francis 2014, Vol. 4, (3) : 549-560
Trupp, Miles; Jonsson, Pär; Öhrfelt, Annika; et al.
2013
OnPLS integration of transcriptomic, proteomic and metabolomic data shows multi-level oxidative stress responses in the cambium of transgenic hipI- superoxide dismutase Populus plants
BMC Genomics
, BioMed Central 2013, Vol. 14
Srivastava, Vaibhav; Obudulu, Ogonna; Bygdell, Joakim; et al.
2012
Validated and Predictive Processing of Gas Chromatography-Mass Spectrometry Based Metabolomics Data for Large Scale Screening Studies, Diagnostics and Metabolite Pattern Verification
Metabolites
, Basel: MDPI 2012, Vol. 2 : 796-817
Thysell, Elin; Chorell, Elin; Svensson, Michael B; et al.
2012
Validated and predictive processing of gas chromatography-mass spectra screening studies, diagnostics and metabolite pattern verification
Metabolites
, M D P I AG 2012, Vol. 2, (4) : 796-817
Thysell, Elin; Chorell, Elin; Svensson, Michael; et al.
2012
Vegetabile material, plants and a method of producing a plant having altered lignin properties
Trygg, Johan; Hertzberg, Magnus; Sundberg, Björn; et al.
2011
Metabolite signature during short-day induced growth cessation in populus
Frontiers in Plant Science
, Frontiers Media S.A. 2011, Vol. 2
Kusano, Miyako; Jonsson, Pär; Fukushima, Atsushi; et al.
2010
Changes in diurnal patterns within the
Populus
transcriptome and metabolome in response to photoperiod variation
Plant, Cell and Environment
, Vol. 33, (8) : 1298-1313
Hoffman, Daniel E.; Jonsson, Pär; Bylesjö, Max; et al.
2009
Evaluation of a protocol for metabolic profiling studies on human blood plasma by combined ultra-performance liquid chromatography/mass spectrometry: From extraction to data analysis
Analytical Biochemistry
, Elsevier 2009, Vol. 372, (2) : 237-249
Bruce, Stephen J; Jonsson, Pär; Antti, Henrik; et al.
2007
A Multivariate Screening Strategy for Investigating Metabolic Effects of Strenuous Physical Exercise in Human Serum
Journal of Proteome Research
, American Chemical Society 2007, Vol. 6, (6) : 2113-2120
Chorell, Elin; Thysell, Elin; Jonsson, Pär; et al.
2007
Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana
BMC Systems Biology
, Vol. 1, (53) : 1-17
Kusano, Miyako; Fukushima, Atsushi; Arita, Masanori; et al.
2007
Application of a metabolomic method combining one-dimensional and two-dimensional gas chromatography-time-of-flight/mass spectrometry to metabolic phenotyping of natural variants in rice
Journal of chromatography. B
, Amsterdam: Elsevier 2007, Vol. 855, (1) : 71-79
Kusano, Miyako; Fukushima, Atsushi; Kobayashi, Makoto; et al.
2007
Reliable Profile Detection in Comparative Metabolomics
Omics
, Mary Ann Liebert 2007, Vol. 11, (2) : 209-224
Thysell, Elin; Pohjanen, Elin; Lindberg, Johan; et al.
2006
Statistical multivariate metabolite profiling for aiding biomarker pattern detection and mechanistic interpretations in GC/MS based metabolomics
Metabolomics
, Vol. 2, (4) : 257-68
Chorell, Elin; Thysell, Elin; Lindberg, Johan; et al.
2006
Dynamic modification of blood erythrocytes metabolism based on GC/TOF-MS analysis
Jiye, A; Granström, Micael; Marklund, Stefan; et al.
2006
Predictive metabolite profiling applying hierarchical multivariate curve resolution to GC-MS data: a potential tool for multi-parametric diagnosis
Journal of Proteome Research
, American Chemical Society 2006, Vol. 5, (6) : 1407-1414
Jonsson, Pär; Sjövik-Johansson, Elin; Wuolikainen, Anna; et al.
2006
A strategy for modelling dynamic responses in metabolic samples characterized by GC/MS
Metabolomics
, Vol. 2, (3) : 135-143
Jonsson, Pär; Stenlund, Hans; Moritz, Thomas; et al.
2006
II.2 Chemometrics in Metabolomics - An Introduction
Plant Metabolomics: Biotechnology in Agriculture and Forestry 57
, Springer Verlag 2006 : 117-128
Trygg, Johan; Gullberg, J; Johansson, A I; et al.
2005
Extraction and GC/MS analysis of the human blood plasma metabolome
ANALYTICAL CHEMISTRY
, Vol. 77, (24) : 8086-94
Jiye, A; Trygg, Johan; Gullberg, Jonas; et al.
2005
Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets
The Analyst
, Vol. 130, (5) : 701-707
Jonsson, Pär; Bruce, Stephen J; Moritz, Thomas; et al.
2005
High-throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses
Analytical Chemistry
, Vol. 77, (17) : 5635-5642
Jonsson, Pär; Johansson, Annika I.; Gullberg, Jonas; et al.
2005
Summary recommendations for standardization and reporting of metabolic analyses: The Standard Metabolic Reporting Structures (SMRS) working group outlines its vision for an open,community-driven specification for the standardization and reporting of metabolic studies
Nature Biotechnology
, Vol. 23 : 833-8
Lindon, John C; Nicholson, Jeremy K; Holmes, Elaine; et al.
2004
Design of experiments: an efficient strategy to identify factors influencing extraction and derivatization of Arabidopsis thaliana samples in metabolomic studies with gas chromatography/mass spectrometry
Analytical Biochemistry
, Vol. 331, (2) : 283-295
Gullberg, Jonas; Jonsson, Pär; Nordström, Anders; et al.
2004
A strategy for identifying differences in large series of metabolomic samples analyzed by GC/MS
Analytical Chemistry
, Columbus, OH: American Chemical Society 2004, Vol. 76, (6) : 1738-1745
Jonsson, Pär; Gullberg, Jonas; Nordström, Anders; et al.
2004
Strategies for implementation and validation of on-line models for multivariate monitoring and control of wood chip properties
Journal of Chemometrics
, Vol. 18, (3-4) : 203-7
Jonsson, Pär; Sjöström, Michael; Wallbäcks, Lars; et al.
Peritoneal infection after colorectal cancer surgery induces substantial alterations in postoperative protein levels: an exploratory study
Grahn, Oskar; Holmgren, Klas; Jonsson, Pär; et al.
Preoperative biomarkers related to inflammation identify high-risk anastomoses in surgery for rectal cancer: an explorative study on patients with colorectal cancer
Holmgren, Klas; Jonsson, Pär; Lundin, Christina; et al.
Modeling of time dependent toxicological responses in urinary GC/MS data
Jonsson, Pär; Stenlund, Hans; Moritz, Thomas; et al.
Metabolite biomarkers of typhoid chronic carriage
Näsström, Elin; Jonsson, Pär; Johansson, Anders; et al.
Processing of mass spectrometry based metabolomics data for large scale screening studies and diagnostics
Thysell, Elin; Chorell, Elin; Svensson, Michael B.; et al.
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