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Umeå universitet
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Personalbild Mattias Forsell

Mattias Forsell

Vi studerar kroppens immunförsvar och hur det reagerar för att skapa skyddande immunitet efter infektion eller vaccination. 

Vetenskaplig meritering: Docent

Kontakt

E-post
mattias.forsell@umu.se
Telefon
090-785 32 08

Verksam vid

Anknytning
Professor vid Institutionen för klinisk mikrobiologi Enhet: Biomedicinsk laboratorievetenskap, Avdelningen för infektion och immunologi
Plats
M, Universitetssjukhuset by 6, 6C106 Umeå universitet, 901 85 Umeå

Mer om forskargruppen Forsell

Semimethylation is a feature of diffuse large B-cell lymphoma, and subgroups with poor prognosis are characterized by global hypomethylation and short telomere length
Clinical Epigenetics, BioMed Central (BMC) 2024, Vol. 16, (1)
Carlund, Olivia; Thörn, Elina; Osterman, Pia; et al.
Olfactory dysfunction as an early predictor for post-COVID condition at 1-year follow-up
Brain and Behavior, John Wiley & Sons 2024, Vol. 14, (6)
Granvik, Christoffer; Andersson, Sara; Andersson, Linus; et al.
Intravenous immunoglobulin therapy for COVID-19 in immunocompromised patients: a retrospective cohort study
International Journal of Infectious Diseases, Elsevier 2024, Vol. 144
Gröning, Remigius; Walde, Jonatan; Ahlm, Clas; et al.
Modulation of innate immune response to mRNA vaccination after SARS-CoV-2 infection or sequential vaccination in humans
JCI Insight, American Society For Clinical Investigation 2024, Vol. 9, (9)
Hellgren, Fredrika; Rosdahl, Anja; Cerveira, Rodrigo Arcoverde; et al.
SARS-CoV-2 infection induces hyaluronan production in vitro and hyaluronan levels in COVID-19 patients relate to morbidity and long-term lung impairment: a prospective cohort study
mBio, American Society for Microbiology 2024, Vol. 15, (10)
Hellman, Urban; Rosendal, Ebba; Lehrstrand, Joakim; et al.
Hybrid capture-based next-generation sequencing of new and old world Orthohantavirus strains and wild-type Puumala isolates from humans and bank voles
Journal of Clinical Virology, Elsevier 2024, Vol. 172
Rosenbaum, William; Bovinder Ylitalo, Erik; Castel, Guillaume; et al.
Direct and indirect effects of Puumala hantavirus on platelet function
Thrombosis Research, Vol. 233 : 41-54
Waltraud, Schrottmaier; Schmuckenschlager, Anna; Thunberg, Therese; et al.
High prevalence of persistent symptoms and reduced health-related quality of life 6 months after COVID-19
Frontiers in Public Health, Frontiers Media S.A. 2023, Vol. 11
Ahmad, Irma; Edin, Alicia; Granvik, Christoffer; et al.
Risk factors for impaired respiratory function post COVID-19: a prospective cohort study of nonhospitalized and hospitalized patients
Journal of Internal Medicine, John Wiley & Sons 2023, Vol. 293, (5) : 600-614
Björsell, Tove; Sundh, Josefin; Lange, Anna; et al.
SARS-CoV-2-related mortality decrease in nursing home residents given multiple COVID-19 boosters
The Lancet - Infectious diseases, Elsevier 2023, Vol. 23, (10) : e393-e394
Blom, Kim; Fjällström, Peter; Molnár, Christian; et al.
Progress in vaccine development for infectious diseases: a Keystone Symposia report
Annals of the New York Academy of Sciences, John Wiley & Sons 2023, Vol. 1524, (1) : 65-86
Cable, Jennifer; Graham, Barney S.; Koup, Richard A.; et al.
Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages
Nature Communications, Springer Nature 2023, Vol. 14, (1)
Chernyshev, Mark; Sakharkar, Mrunal; Connor, Ruth I.; et al.
Immune response to SARS-CoV-2 mRNA vaccination in multiple sclerosis patients after rituximab treatment interruption
Frontiers in Immunology, Frontiers Media S.A. 2023, Vol. 14
Gröning, Remigius; Dernstedt, Andy; Ahlm, Clas; et al.
Extracellular galectin 4 drives immune evasion and promotes T-cell apoptosis in pancreatic cancer
Cancer immunology research, American Association for Cancer Research 2023, Vol. 11, (1) : 72-92
Lidström, Tommy; Cumming, Joshua; Gaur, Rahul; et al.
Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody
Science Translational Medicine, American Association for the Advancement of Science (AAAS) 2023, Vol. 15, (700)
Mittler, Eva; Serris, Alexandra; Esterman, Emma S.; et al.
Vaccine-induced correlate of protection against fatal COVID-19 in older and frail adults during waves of neutralization-resistant variants of concern: an observational study
The Lancet Regional Health: Europe, Elsevier 2023, Vol. 30
Vikström, Linnea; Fjällström, Peter; Gwon, Yong-Dae; et al.
At-home sampling to meet geographical challenges for serological assessment of SARS-CoV-2 exposure in a rural region of northern Sweden, March to May 2021: a retrospective cohort study
Eurosurveillance, European Centre for Disease Control and Prevention (ECDC) 2023, Vol. 28, (13)
Wigren, Julia; Vikström, Linnea; Rosendal, Ebba; et al.
Seroprevalence of SARS-CoV-2 in Sweden, April 26 to May 9, 2021
Scientific Reports, Nature Publishing Group 2022, Vol. 12, (1)
Beser, Jessica; Galanis, Ilias; Enkirch, Theresa; et al.
Immune responses after omicron infection in triple-vaccinated health-care workers with and without previous SARS-CoV-2 infection
The Lancet - Infectious diseases, Vol. 22, (7) : 943-945
Blom, Kim; Marking, Ulrika; Havervall, Sebastian; et al.
Probabilistic classification of anti-SARS-CoV-2 antibody responses improves seroprevalence estimates
Clinical & Translational Immunology (CTI), John Wiley & Sons 2022, Vol. 11, (3)
Castro Dopico, Xaquin; Muschiol, Sandra; Grinberg, Nastasiya F.; et al.
Hierarchical Clustering and Trajectory Analyses Reveal Viremia-Independent B-Cell Perturbations in HIV-2 Infection
Cells, MDPI 2022, Vol. 11, (19)
Johansson, Emil; Kerkman, Priscilla; Scharf, Lydia; et al.
Recall of preexisting cross-reactive B cell memory after Omicron BA.1 breakthrough infection
Science immunology, American Association for the Advancement of Science 2022, Vol. 7, (73)
Kaku, Chengzi I.; Bergeron, Alan J.; Ahlm, Clas; et al.
Broad anti–SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 vaccination
Science, American Association for the Advancement of Science 2022, Vol. 375, (6584) : 1041-1047
Kaku, Chengzi I.; Champney, Elizabeth R.; Normark, Johan; et al.
Convalescent plasma treatment in severely immunosuppressed patients hospitalized with COVID-19: an observational study of 28 cases
Infectious Diseases, Taylor & Francis Group 2022, Vol. 54, (4) : 283-291
Ljungquist, Oskar; Lundgren, Maria; Iliachenko, Elena; et al.
Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses
Science Translational Medicine, American Association for the Advancement of Science 2022, Vol. 14, (636)
Mittler, Eva; Wec, Anna Z.; Tynell, Janne; et al.
Serine protease inhibitors restrict host susceptibility to SARS-CoV-2 infections
mBio, American Society for Microbiology 2022, Vol. 13, (3)
Rosendal, Ebba; Mihai, Ionut Sebastian; Becker, Miriam; et al.
Serum concentration of extracellular cold-inducible RNA-binding protein is associated with respiratory failure in COVID-19
Frontiers in Immunology, Frontiers Media S.A. 2022, Vol. 13
Schagatay, Felix; Diamant, Klara; Lidén, Mats; et al.
Clinical and genomic characterisation of a fatal Puumala orthohantavirus case with low levels of neutralising antibodies
Infectious Diseases, Vol. 54, (10) : 766-772
Tuiskunen-Bäck, Anne; Rasmuson, Johan; Thunberg, Therese; et al.
Single-Dilution COVID-19 Antibody Test with Qualitative and Quantitative Readouts
mSphere, American Society for Microbiology 2021, Vol. 6, (2)
Bortz, Robert H.; Florez, Catalina; Laudermilch, Ethan; et al.
Airway antibodies emerge according to COVID-19 severity and wane rapidly but reappear after SARS-CoV-2 vaccination
JCI Insight, American Society for Clinical Investigation 2021, Vol. 6, (22)
Cagigi, Alberto; Yu, Meng; Österberg, Björn; et al.
The Tonsil Lymphocyte Landscape in Pediatric Tonsil Hyperplasia and Obstructive Sleep Apnea
Frontiers in Immunology, Frontiers Media S.A. 2021, Vol. 12
Carrasco, Anna; Sjölander, Isabella; Van Acker, Aline; et al.
Regulation of Decay Accelerating Factor Primes Human Germinal Center B Cells for Phagocytosis
Frontiers in Immunology, Frontiers Media S.A. 2021, Vol. 11
Dernstedt, Andy; Leidig, Jana; Holm, Anna; et al.
Convalescence plasma treatment of COVID-19: results from a prematurely terminated randomized controlled open-label study in Southern Sweden
BMC Research Notes, BioMed Central 2021, Vol. 14, (1)
Holm, Karin; Lundgren, Maria N.; Kjeldsen-Kragh, Jens; et al.
Generation of plasma cells and CD27-IgD- B cells during hantavirus infection is associated with distinct pathological findings
Clinical & Translational Immunology (CTI), John Wiley & Sons 2021, Vol. 10
Kerkman, Priscilla; Dernstedt, Andy; Tadala, Lalitha; et al.
Evaluation of 11 SARS-CoV-2 antibody tests by using samples from patients with defined IgG antibody titers
Scientific Reports, Nature Publishing Group 2021, Vol. 11, (1)
Lagerqvist, Nina; Maleki, Kimia T.; Verner-Carlsson, Jenny; et al.
MAIT cell activation is associated with disease severity markers in acute hantavirus infection
Cell Reports Medicine, Saunders Elsevier 2021, Vol. 2, (3)
Maleki, Kimia T.; Tauriainen, Johanna; García, Marina; et al.
Heterologous ChAdOx1 nCoV-19 and mRNA-1273 Vaccination
New England Journal of Medicine, Massachusetts Medical Society 2021, Vol. 385, (11) : 1049-1051
Normark, Johan; Vikström, Linnea; Yong-Dae, Gwon; et al.
Platelets mediate serological memory to neutralize viruses in vitro and in vivo
Blood Advances, American Society of Hematology 2020, Vol. 4, (16) : 3971-3976
Waltraud, Schrottmaier C.; Salzmann, Manuel; Badrnya, Sigrun; et al.
Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine
Proceedings of the National Academy of Sciences of the United States of America, Washington: National Academy of Science 2020, Vol. 117, (12) : 6675-6685
Wec, Anna Z.; Haslwanter, Denise; Abdiche, Yasmina N.; et al.
Growth-inhibition of cell lines derived from B cell lymphomas through antagonism of serotonin receptor signaling
Scientific Reports, Nature Publishing Group 2019, Vol. 9
Kolan, Shrikant S; Lidström, Tommy; Mediavilla, Tomás; et al.
Platelet-stored antibodies potently diminish viral infection in vitro and in vivo
Acta Physiologica, John Wiley & Sons 2019, Vol. 227, (S718) : 187-187
Schrottmaier, Waltraud C.; Salzmann, M.; Badrnya, S.; et al.
B cell profiling in malaria reveals expansion and remodeling of CD11c+ B cell subsets
JCI Insight, American Society for Clinical Investigation 2019, Vol. 4, (9)
Sundling, Christopher; Ronnberg, Caroline; Yman, Victor; et al.
Regulation of Subunit-Specific Germinal Center B Cell Responses to the HIV-1 Envelope Glycoproteins by Antibody-Mediated Feedback
Frontiers in Immunology, Frontiers Media S.A. 2017, Vol. 8
Forsell, Mattias N. E.; Kvastad, Linda; Sedimbi, Saikiran K.; et al.
The B cell response towards Puumala virus infection: can B cells be infected?
Scandinavian Journal of Immunology, John Wiley & Sons 2017, Vol. 86, (4) : 260-260
Kerkman, Priscilla; Tuiskunen-Bäck, Anne; Dernstedt, Andy; et al.
Modulation of lymphoma growth by a selective serotonin receptor antagonist
Scandinavian Journal of Immunology, John Wiley & Sons 2017, Vol. 86, (4) : 343-343
Kolan, Shrikant S.; Lidström, Tommy; Björk, Karl; et al.
The Wiskott-Aldrich syndrome protein regulates antigen processing and presentation by dendritic cells
Scandinavian Journal of Immunology, WILEY 2017, Vol. 86, (4) : 254-255
Oliveira, Mariana; Baptista, Marisa; Keszei, Marton; et al.
Activation of circulating platelets leads to innate-like delivery of potent antiviral antibodies
Scandinavian Journal of Immunology, John Wiley & Sons 2017, Vol. 86, (4) : 278-278
Waltraud, Schrottmaier; Anna-Liisa, Luik; Manuel, Salzmann; et al.
Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells
Nature Communications, Vol. 7
Baptista, Marisa A. P.; Keszei, Marton; Oliveira, Mariana; et al.
Elevated plasma levels of NET components in men with severe COVID-19 correlates to increased amounts of IL-18
Backman, Emelie; Gröning, Remigius; Lind, Alicia; et al.
Variable immune response to SARS-CoV-2 mRNA vaccination in multiple sclerosis after rituximab treatment interruption
Gröning, Remigius; Dernstedt, Andy; Gardfjäll, Jenny; et al.
Visa publikationer i DiVA

Forskargrupper

Forskningsledare
Forskning om Covid-19
Forskningsledare
Mattias Forsell Lab
Gruppmedlem
Katarina Olofsson

Vidare läsning

Mattias Forsell: Vaccinets livräddande molekyler

Den kunskap forskarna fått genom Covid-19, kan vara till nytta vid framtida pandemier.

Mattias Forsell: Vad säger antikroppstest om vårt immunförsvar?

Antikroppar är protein som bildas mot främmande ämnen som virus, och kan skräddarsys mot nya infektioner.

Forskar kring immunförsvarets reaktion på covid-19

Mattias Forsell och hans kollegor har startat en biobank - där följs de som diagnostiserats med covid-19.

Film: Forskning på ett ögonblick med Mattias Forsell
Forskning på ett ögonblick med Mattias Forsell

Han studerar kroppens immunförsvar och hur det reagerar efter infektion eller vaccination.