Kristoffer Sahlholm

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090-786 67 77

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Universitetslektor vid Institutionen för medicinsk och translationell biologi Enhet: Grupp Kristoffer Sahlholm, Lärare D1-flygeln

hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå

Neurophysiological treatment effects of mesdopetam, pimavanserin and clozapine in a rodent model of Parkinson's disease psychosis

Neurotherapeutics, Elsevier 2024, Vol. 21, (2)

Stan, Tiberiu Loredan; Ronaghi, Abdolaziz; Barrientos, Sebastian A.; et al.

Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2

Frontiers in Pharmacology, Frontiers Media S.A. 2023, Vol. 14

Burström, Viktor; Ågren, Richard; Betari, Nibal; et al.

Remote local photoactivation of morphine produces analgesia without opioid-related adverse effects

British Journal of Pharmacology, John Wiley & Sons 2023, Vol. 180, (7) : 958-974

López-Cano, Marc; Font, Joan; Aso, Ester; et al.

Unique effect of clozapine on adenosine A_2A-dopamine D₂ receptor heteromerization

Biomedicine and Pharmacotherapy, Elsevier 2023, Vol. 160

Valle-León, Marta; Casajuana-Martin, Nil; del Torrent, Claudia Llinas; et al.

In vitro comparison of ulotaront (SEP-363856) and ralmitaront (RO6889450): two TAAR1 agonist candidate antipsychotics

International Journal of Neuropsychopharmacology, Oxford University Press 2023, Vol. 26, (9) : 599-606

Ågren, Richard; Betari, Nibal; Saarinen, Marcus; et al.

An E280K Missense Variant in KCND3/Kv4.3—Case Report and Functional Characterization

International Journal of Molecular Sciences, MDPI 2023, Vol. 24, (13)

Ågren, Richard; Geerdink, Niels; Brunner, Han G.; et al.

Major genetic risk factors for Dupuytren's disease are inherited from neandertals

Molecular biology and evolution, Oxford University Press 2023, Vol. 40, (6)

Ågren, Richard; Patil, Snehal; Zhou, Xiang; et al.

TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT1A receptor agonist SEP-383856

Neuropsychopharmacology, Springer Nature 2022, Vol. 47 : 2319-2329

Saarinen, Marcus; Mantas, Ioannis; Flais, Ivana; et al.

Evidence for two modes of binding of the negative allosteric modulator SB269,652 to the dopamine D2 receptor

Biomedicines, MDPI 2022, Vol. 10, (1)

Ågren, Richard; Sahlholm, Kristoffer

Synthetic corticosteroids as tryptophan hydroxylase stabilizers

Future Medicinal Chemistry, Future Science Ltd. 2021, Vol. 13, (17) : 1465-1474

Betari, Nibal; Teigen, Knut; Sahlholm, Kristoffer; et al.

Interaction of ligands for pet with the dopamine d3 receptor: in silico and in vitro methods

Biomolecules, MDPI 2021, Vol. 11, (4)

Hsieh, Chia-Ju; Riad, Aladdin; Lee, Ji Youn; et al.

V374A KCND3 Pathogenic Variant Associated With Paroxysmal Ataxia Exacerbations

Neurology Genetics, American Academy of Neurology 2021, Vol. 7, (1)

Paucar, Martin; Ågren, Richard; Li, Tianyi; et al.

Mechanistic insights into dopaminergic and serotonergic neurotransmission: concerted interactions with helices 5 and 6 drive the functional outcome

Chemical Science, Royal Society of Chemistry 2021, Vol. 12, (33) : 10990-11003

Stepniewski, Tomasz Maciej; Mancini, Arturo; Ågren, Richard; et al.

Decreased striatal adenosine A_2A-dopamine D₂ receptor heteromerization in schizophrenia

Neuropsychopharmacology, Springer Nature 2021, Vol. 46 : 665-672

Valle-Leon, Marta; Callado, Luis F.; Aso, Ester; et al.

G protein-coupled receptor kinase-2 confers isoform-specific calcium sensitivity to dopamine D₂ receptor desensitization

The FASEB Journal, John Wiley & Sons 2021, Vol. 35, (11)

Ågren, Richard; Sahlholm, Kristoffer

Dopamine d₂ receptor agonist binding kinetics: role of a conserved serine residue

International Journal of Molecular Sciences, MDPI 2021, Vol. 22, (8)

Ågren, Richard; Stepniewski, Tomasz Maciej; Zeberg, Hugo; et al.

Discovery and biological characterization of a novel scaffold for potent inhibitors of peripheral serotonin synthesis

Future Medicinal Chemistry, Future Science 2020, Vol. 12, (16) : 1461-1474

Betari, Nibal; Sahlholm, Kristoffer; Ishizuka, Yuta; et al.

Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole-In Vitro and In Vivo Investigations

Frontiers in Pharmacology, Frontiers Media S.A. 2020, Vol. 11

Betari, Nibal; Sahlholm, Kristoffer; Morato, Xavier; et al.

A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans

Current Biology, Elsevier 2020, Vol. 30, (17) : 3465-3469

Zeberg, Hugo; Dannemann, Michael; Sahlholm, Kristoffer; et al.

Voltage-Dependent Dopamine Potency at D-1-Like Dopamine Receptors

Frontiers in Pharmacology, Frontiers Media S.A. 2020, Vol. 11

Ågren, Richard; Sahlholm, Kristoffer

Ligand with Two Modes of Interaction with the Dopamine D-2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism

ACS Chemical Neuroscience, American Chemical Society (ACS) 2020, Vol. 11, (19) : 3130-3143

Ågren, Richard; Zeberg, Hugo; Stępniewski, Tomasz Maciej; et al.

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Forskningsledare

Kristoffer Sahlholm-forskargrupp