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Umeå universitet
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Personalbild Jonas Nilsson

Jonas Nilsson

Vår grupp driver projekt för anpassa cancermedicin och avkoda tumörinformation till kunskap som leder till bättre behandlingar.

Vetenskaplig meritering: Docent

Kontakt

E-post
jonas.a.nilsson@umu.se
Telefon
090-785 85 61

Verksam vid

Anknytning
Forskare vid Institutionen för diagnostik och intervention Enhet: Onkologi
Plats
Målpunkt M31, Byggnad 6M, plan 3, Norrlands universitetssjukhus, Translationellt forskningscentrum (TRC) Umeå universitet, 901 85 Umeå

Ett forskningsfokus handlar om interaktionen mellan cancerceller och deras mikromiljö, och hur tumören kan kringgå immunförsvaret, så kallad immunredigering. Det handlar också om den nya linjen av immunterapier riktade mot dem, t.ex. immunkontrollpunktshämmare.

KRAS G12C-mutant driven non-small cell lung cancer (NSCLC)
Critical reviews in oncology/hematology, Elsevier 2024, Vol. 195
Rosell, Rafael; Codony-Servat, Jordi; González, Jessica; et al.
Use of CAM among cancer patients: results of a regional survey in Sweden
BMC Complementary Medicine and Therapies, BioMed Central (BMC) 2023, Vol. 23, (1)
Källman, Mikael; Bergström, Stefan; Carlsson, Tobias; et al.
Detection and localization of early- and late-stage cancers using platelet RNA
Cancer Cell, Elsevier 2022, Vol. 40, (9) : 999-1009.e6
In ’t Veld, Sjors G.J.G.; Arkani, Mohammad; Post, Edward; et al.
Clinical and biological relevance of the transcriptomic-based prostate cancer metastasis subtypes MetA-C
Molecular Oncology, John Wiley & Sons 2022, (4)
Thysell, Elin; Köhn, Linda; Semenas, Julius; et al.
Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma
Cell Reports Medicine, Elsevier 2020, Vol. 1, (7)
Sol, Nik; 't Veld, Sjors G. J. G. in; Vancura, Adrienne; et al.
Platelets harbor prostate cancer biomarkers and the ability to predict therapeutic response to abiraterone in castration resistant patients
The Prostate, Wiley-Blackwell 2018, Vol. 78, (1) : 48-53
Tjon-Kon-Fat, Lee-Ann; Lundholm, Marie; Schröder, Mona; et al.
Platelet RNA in Cancer Diagnostics
Seminars in Thrombosis and Hemostasis, THIEME MEDICAL PUBL INC 2018, Vol. 44, (2) : 135-141
Tjon-Kon-Fat, Lee-Ann; Sol, Nik; Wurdinger, Thomas; et al.
Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets
Cancer Cell, Elsevier 2017, Vol. 32, (2) : 238-252
Best, Myron G.; Sol, Nik; 't Veld, Sjors G. J. G. In; et al.
The prognostic value of pre-treatment leukocytosis in patients with previously treated, stage IIIB/IV non-small cell lung cancer treated with the IGF-1R pathway modulator AXL1717 or docetaxel: a retrospective analysis of a phase II trial
Asian Pacific Journal of Cancer Prevention, Vol. 18, (6) : 1555-1560
Holgersson, Georg; Bergqvist, Michael; Nilsson, R. Jonas A.; et al.
The prognostic value of pre-treatment thrombocytosis in two cohorts of patients with non-small cell lung cancer treated with curatively intended chemoradiotherapy
Neoplasma (Bratislava), Bratislava: AEPress 2017, Vol. 64, (6) : 909-915
Holgersson, Georg; Bergström, Stefan; Hallqvist, Anders; et al.
Liquid biopsies in lung cancer: time to implement research technologies in routine care?
Annals of Translational Medicine, AME Publishing Company 2017, Vol. 5, (13)
Köhn, Linda; Johansson, Mikael; Grankvist, Kjell; et al.
miR-129-3p controls centrosome number in metastatic prostate cancer cells by repressing CP110
Oncotarget, Vol. 7, (13) : 16676-16687
Bijnsdorp, Irene V.; Hodzic, Jasmina; Lagerweij, Tonny; et al.
Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer
Oncotarget, Vol. 7, (1) : 1066-1075
Nilsson, R. Jonas A.; Karachaliou, Niki; Berenguer, Jordi; et al.
RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics
Cancer Cell, Vol. 28, (5) : 666-676
Best, Myron G.; Sol, Nik; Kooi, Irsan; et al.
Tumor-educated platelets allow for multiclass liquid biopsy-based diagnosis of cancer
Cancer Research, American Association for Cancer Research 2015, Vol. 75, (Suppl. 15)
Best, Myron; Sol, Nik; Kooi, Irsan; et al.
Allowance of tumor-educated platelets for multiclass liquid biopsy-based diagnosis of cancer
Journal of Clinical Oncology, American Society of Clinical Oncology 2015, Vol. 33, (15, suppl.)
Best, Myron; Sol, Nik; Kooi, Irsan; et al.
Multiplex functional bioluminescent reporters using gaussia luciferase fused to epitope tags in an immunobinding assay
Bioluminescent imaging: methods and protocols, Humana Press 2014 : 231-247
Van Rijn, Sjoerd; Würdinger, Thomas; Nilsson, R. Jonas A.
Effects of the Selective MPS1 Inhibitor MPS1-IN-3 on Glioblastoma Sensitivity to Antimitotic Drugs
Journal of the National Cancer Institute, Oxford University Press 2013, Vol. 105, (17) : 1322-1331
Tannous, Bakhos A.; Kerami, Mariam; Van der Stoop, Petra M.; et al.
Functional multiplex reporter assay using tagged Gaussia luciferase
Scientific Reports, Nature Publishing Group 2013, Vol. 3
Van Rijn, S.; Nilsson, Jonas; Noske, D. P.; et al.
Transcription Factor Activity Analysis Using a Functional Multiplex Gaussia Luciferase-Based Reporter Assay
Molecular Therapy, Nature Publishing Group 2013, Vol. 21 : S123-S124
van Rijn, Sjoerd; Nilsson, Jonas; Noske, David P.; et al.
Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor-related apoptosis-inducing ligand and induces an alternative cell death pathway.
Neuro-Oncology, Vol. 13, (11) : 1213-1224
Badr, Christian E; Wurdinger, Thomas; Nilsson, Jonas; et al.
Blood platelets contain tumor-derived RNA biomarkers
Blood, New York: 2011, Vol. 118, (13) : 3680-3683
Nilsson, R. Jonas A.; Balaj, Leonora; Hulleman, Esther; et al.
Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2
PLOS ONE, Vol. 6, (1) : e16282-
Smits, Michiel; Mir, Shahryar E; Nilsson, Jonas; et al.
Paracrine regulation of growth factor signaling by shed leucine-rich repeats and immunoglobulin-like domains 1
Experimental Cell Research, New York: Academic Press 2011, Vol. 317, (4) : 504-512
Yi, Wei; Holmlund, Camilla; Nilsson, Jonas; et al.
miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis
Oncotarget, Impact Journals LLC 2010, Vol. 1, (8) : 710-720
Smits, Michiel; Nilsson, Jonas; Mir, Shahryar E; et al.
Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer.
British journal of cancer, Vol. 100, (10) : 1603-1607
Nilsson, Jonas; Skog, Johan; Nordstrand, Annika; et al.
Establishment and validation of an in vitro co-culture model to study the interactions between bone and prostate cancer cells
Clinical & experimental metastasis, Vol. 26, (8) : 945-953
Nordstrand, Annika; Nilsson, Jonas; Tieva, Åse; et al.
Perinuclear leucine-rich repeats and immunoglobulin-like domain proteins (LRIG1-3) as prognostic indicators in astrocytic tumors
Acta Neuropathologica, Vol. 111, (3) : 238-346
Guo, Dongsheng; Nilsson, Jonas; Haapasalo, Hannu; et al.
The LRIG-family: identification of novel regulators of ErbB signaling with clinical implications in astrocytoma
Umeå University medical dissertations, 1027
Nilsson, Jonas
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
EMBO Journal, Vol. 23, (16) : 3270-3281
Gur, Gal; Rubin, Chanan; Katz, Menachem; et al.
Characterization and tissue-specific expression of human LRIG2
Gene, Vol. 332 : 35-43
Holmlund, Camilla; Nilsson, Jonas; Guo, Dongsheng; et al.
LRIG1 protein in human cells and tissues
Cell and Tissue Research, Vol. 312, (1) : 65-71
Nilsson, Jonas; Starefeldt, Anna; Henriksson, Roger; et al.
Adenovirus type 37 binds to cell surface sialic acid through a charge-dependent interaction
Virology, Elsevier 2002, Vol. 302, (1) : 33-43
Arnberg, Niklas; Kidd, Alistair H; Edlund, Karin; et al.
Is LRIG1 a tumour suppressor gene at chromosome 3p14.3?
Acta Oncologica, Vol. 41, (4) : 352-354
Hedman, Håkan; Nilsson, Jonas; Guo, Dongsheng; et al.
Cloning, characterization and expression of human LIG1
Biochemical and Biophysical Research Communications - BBRC, Vol. 284, (5) : 1155-1161
Nilsson, Jonas; Vallbo, Christina; Guo, Dongsheng; et al.
Visa publikationer i DiVA

Forskargrupper

Forskningsledare
Jonas Nilsson lab