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English
Glenn Björk
Kontakt
E-post
glenn.bjork@umu.se
Telefon
090-785 67 56
Verksam vid
Anknytning
Anknuten som professor emeritus till
Institutionen för molekylärbiologi
Enhet: Grupp Glenn Björk
Plats
6K och 6L, Sjukhusområdet
Umeå universitet, 901 87 Umeå
Publikationer
Publikationer
2017
An unmodified wobble uridine in tRNAs specific for Glutamine, Lysine, and Glutamic acid from Salmonella enterica Serovar Typhimurium results in nonviability-Due to increased missense errors?
PLOS ONE
, Vol. 12, (4)
Nilsson, Kristina; Jäger, Gunilla; Björk, Glenn R.
2016
Transfer RNA Bound to MnmH Protein Is Enriched with Geranylated tRNA - A Possible Intermediate in Its Selenation?
PLOS ONE
, Public Library Science 2016, Vol. 11, (4)
Jäger, Gunilla; Chen, Peng; Björk, Glenn R.
2014
Transfer RNA modification: Presence, synthesis, and function
EcoSal Plus
, American Society for Microbiology 2014, Vol. 6, (1) : 1-68
Björk, Glenn R.; Hagervall, Tord G.
2014
The output of the tRNA modification pathways controlled by the Escherichia coli MnmEG and MnmC enzymes depends on the growth conditions and the tRNA species
Nucleic Acids Research
, Vol. 42, (4) : 2602-2623
Moukadiri, Ismaïl; Garzón, M. -José; Björk, Glenn R.; et al.
2013
The Phenotype of Many Independently Isolated+1 Frameshift Suppressor Mutants Supports a Pivotal Role of the P-Site in Reading Frame Maintenance
PLOS ONE
, Vol. 8, (4) : e60246-
Jäger, Gunilla; Nilsson, Kristina; Björk, Glenn R.
2012
Characterization and Structure of the Aquifex aeolicus Protein DUF752 A BACTERIAL tRNA-METHYLTRANSFERASE (MnmC2) FUNCTIONING WITHOUT THE USUALLY FUSED OXIDASE DOMAIN (MnmC1)
Journal of Biological Chemistry
, Vol. 287, (52) : 43950-43960
Kitamura, Aya; Nishimoto, Madoka; Sengoku, Toru; et al.
2011
Adventures with Frameshift Supressor tRNAs
Lure of Bacterial Genetics: a Tribute to John Roth
, WASHINGTON: American society for microbiology, ASM Press 2011 : 131-140
Björk, Glenn R.
2011
Two groups of phenylalanine biosynthetic operon leader peptides genes: a high level of apparently incidental frameshifting in decoding Escherichia coli pheL
Nucleic Acids Research
, Vol. 39, (8) : 3079-3092
Gurvich, Olga L; Näsvall, S Joakim; Baranov, Pavel V; et al.
2010
Trm112p is a 15-kDa zinc finger protein essential for the activity of two tRNA and one protein methyltransferases in yeast
Journal of Biological Chemistry
, Vol. 285, (24) : 18505-18515
Mazauric, MH; Dirick, L; Purushothaman, SK; et al.
2009
A gripping tale of ribosomal frameshifting: extragenic suppressors of frameshift mutations spotlight P-site realignment
Microbiology and molecular biology reviews
, Vol. 73, (1) : 178-210
Atkins, John F; Björk, Glenn R
2009
Metabolic control through ornithine and uracil of epithelial cell invasion by Shigella flexneri
Microbiology
, Vol. 155, (Pt 8) : 2498-2508
Durand, Jérôme M B; Björk, Glenn R
2009
Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions
Nucleic Acids Research
, Vol. 37, (21) : 7177-7193
Moukadiri, Ismaïl; Prado, Silvia; Piera, Julio; et al.
2009
The ribosomal grip of the peptidyl-tRNA is critical for reading frame maintenance.
Journal of Molecular Biology
, Vol. 385, (2) : 350-367
Näsvall, Joakim S; Nilsson, Kristina; Björk, Glenn R
2008
Eukaryotic wobble uridine modifications promote a functionally redundant decoding system.
Molecular and Cellular Biology
, Vol. 28, (10) : 3301-3312
Johansson, Marcus J O; Esberg, Anders; Huang, Bo; et al.
2007
A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast.
RNA
, Vol. 13, (8) : 1245-55
Björk, Glenn; Huang, Bo; Persson, Olof P; et al.
2007
Diet-dependent depletion of queuosine in tRNAs in Caenorhabditis elegans does not lead to a developmental block.
J Biosci
, Vol. 32, (4) : 747-54
Gaur, Rahul; Björk, Glenn; Tuck, Simon; et al.
2007
Alterations in the two globular domains or in the connecting alpha-helix of bacterial ribosomal protein L9 induces +1 frameshifts.
J Bacteriol
, Vol. 189, (19) : 7024-31
Leipuviene, Ramune; Björk, Glenn R
2007
The Wobble hypothesis revisited: Uridine-5-oxyacetic acid is critical for reading of G-ending codons
RNA: A publication of the RNA Society
, Vol. 13, (12) : 2151-2164
Näsvall, S. Joakim; Chen, Peng; Björk, Glenn R.
2007
Amino acid residues of the Escherichia coli tRNA(m5U54)methyltransferase (TrmA) critical for stability, covalent binding of tRNA and enzymatic activity.
Nucleic Acids Res
, Vol. 35, (10) : 3297-305
Urbonavicius, Jaunius; Jäger, Gunilla; Björk, Glenn R
2006
Structural alterations of the cysteine desulfurase IscS of Salmonella enterica serovar Typhimurium reveal substrate specificity of IscS in tRNA thiolation.
Journal of Bacteriology
, Vol. 188, (8) : 3052-3062
Lundgren, Hans K; Björk, Glenn R
2006
Further insights into the tRNA modification process controlled by proteins MnmE and GidA of Escherichia coli.
Nucleic Acids Res
, Vol. 34, (20) : 5892-905
Yim, Lucía; Moukadiri, Ismaïl; Björk, Glenn; et al.
2005
Transfer RNA modification
EcoSal - Escherichia coli and Salmonella. Cellular and Molecular Biology
, ASM Press, Washington DC 2005 : -
Björk, Glenn
2005
A "gain of function" mutation in a protein mediates production of novel modified nucleosides.
EMBO Journal
, Vol. 24, (10) : 1842-1851
Chen, Peng; Crain, Pamela F; Näsvall, Joakim; et al.
2005
A reduced level of charged tRNAArgmnm5UCU triggers the wild-type peptidyl-tRNA to frameshift.
RNA
, Vol. 11, (5) : 796-807
Leipuviene, Ramune; Björk, Glenn
2005
Effects of mutagenesis in the switch I region and conserved arginines of Escherichia coli MnmE protein, a GTPase involved in tRNA modification
Journal of Biological Chemistry
, Vol. 280, (35) : 30660-30670
Martínez-Vicente, Marta; Yim, Lucía; Villarroya, Magda; et al.
2005
Over expression of a tRNA(Leu) isoacceptor changes charging pattern of leucine tRNAs and reveals new codon reading.
J Mol Biol
, Vol. 354, (1) : 16-24
Sørensen, Michael A; Elf, Johan; Bouakaz, Elli; et al.
2004
Enzymatic conversion of cytidine to lysidine in anticodon of bacterial isoleucyl-tRNA--an alternative way of RNA editing
TIBS -Trends in Biochemical Sciences. Regular ed.
, Amsterdam: Int. union of biochemistry and Elsevier/North-Holland 2004, Vol. 29, (4) : 165-168
Grosjean, Henri; Björk, Glenn
2004
Aminoacylation of the anticodon stem by a tRNA-synthetase paralog: relic of an ancient code?
TIBS -Trends in Biochemical Sciences. Regular ed.
, London: Elsevier 2004, Vol. 29, (10) : 519-522
Grosjean, Henri; de Crécy-Lagard, Valérie; Björk, Glenn R
2004
The conserved Cys-X1-X2-Cys motif present in the TtcA protein is required for the thiolation of cytidine in position 32 of tRNA from Salmonella enterica serovar Typhimurium.
Journal of Bacteriology
, Vol. 186, (3) : 750-757
Jäger, Gunilla; Leipuviene, Ramune; Pollard, Michael; et al.
2004
Formation of thiolated nucleosides present in tRNA from Salmonella enterica serovar Typhimurium occurs in two principally distinct pathways.
Journal of Bacteriology
, Vol. 186, (3) : 758-766
Leipuviene, Ramune; Qian, Qiang; Björk, Glenn
2004
The modified wobble nucleoside uridine-5-oxyacetic acid in tRNAPro(cmo5UGG) promotes reading of all four proline codons in vivo.
RNA: A publication of the RNA Society
, Vol. 10, (10) : 1662-1673
Näsvall, Joakim; Chen, Peng; Björk, Glenn
2002
A cytosolic tRNA with an unmodified adenosine in the wobble position reads a codon ending with the non-complementary nucleoside cytidine
Journal of Molecular Biology
, Vol. 317, (4) : 481-492
Chen, Peng; Qian, Qiang; Zhao, Shaoping; et al.
2002
The cysteine desulfurase IscS is required for synthesis of all five thiolated nucleosides present in tRNA from Salmonella enterica serovar typhimurium
Journal of Bacteriology
, American Society for Microbiology 2002, Vol. 184, (24) : 6830-6835
Nilsson, Kristina; Lundgren, Hans K.; Hagervall, Tord G.; et al.
2001
A primordial tRNA modification required for the evolution of life?
EMBO Journal
, Vol. 20, (1-2) : 231-239
Björk, Glenn R; Jacobsson, Kerstin; Nilsson, Kristina; et al.
1989
Prevention of translational frameshifting by the modified nucleoside 1-methylguanosine
Science
, Vol. 244, (4907) : 986-989
Björk, Glenn R; Wikström, P M; Byström, Anders S
1989
Differentially expressed trmD ribosomal protein operon of Escherichia coli is transcribed as a single polycistronic mRNA species
Journal of Molecular Biology
, Academic Press 1989, Vol. 208, (4) : 575-586
Byström, Anders S; von Gabain, A; Björk, Glenn R
1988
Non-autogenous control of ribosomal protein synthesis from the trmD operon in Escherichia coli
Journal of Molecular Biology
, Vol. 203, (1) : 141-152
Wikström, P M; Byström, Anders S; Björk, Glenn R
1984
Modified nucleosides in RNA-their formation and function
Processing of RNA
, CRC Press 1984 : 291-330
Björk, Glenn R
1983
The nucleotide sequence of an Escherichia coli operon containing genes for the tRNA(m1G)methyltransferase, the ribosomal proteins S16 and L19 and a 21-K polypeptide
EMBO Journal
, Oxford University Press 1983, Vol. 2, (6) : 899-905
Byström, Anders S; Hjalmarsson, Karin J; Wikström, P Mikael; et al.
1983
Purification and characterization of transfer RNA (guanine-1)methyltransferase from Escherichia coli
Journal of Biological Chemistry
, American Society for Biochemistry and Molecular Biology 1983, Vol. 258, (2) : 1343-1351
Hjalmarsson, Karin J.; Byström, Anders S; Björk, Glenn R
1982
Chromosomal location and cloning of the gene (trmD) responsible for the synthesis of tRNA (m1G) methyltransferase in Escherichia coli K-12.
Molecular General Genetics
, Vol. 188, (3) : 440-446
Byström, Anders S; Björk, Glenn R
1982
The structural gene (trmD) for the tRNA(m1G)methyltransferase is part of a four polypeptide operon in Escherichia coli K-12
Molecular General Genetics
, Springer-Verlag New York 1982, Vol. 188, (3) : 447-454
Byström, Anders S; Björk, Glenn R
Ribosome slippage induced by mutations in the ribosomal protein L9
Leipuviene, Ramune; Björk, Glenn R
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