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Umeå universitet
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Huvudmenyn dold.

Bethany van Guelpen

Vetenskaplig meritering: Docent

Kontakt

E-post
bethany.vanguelpen@umu.se
Telefon
090-785 28 09

Verksam som

Anknytning
Professor, specialistutbildad läkare vid Institutionen för diagnostik och intervention Enhet: Onkologi
Plats
27C, Målpunkt QC11, NUS, Norrlands universitetssjukhus Umeå universitet, 901 85 Umeå
mRNA extracted from frozen buffy coat samples stored long term in tubes with no RNA preservative shows promise for downstream sequencing analyses
PLOS ONE, Public Library of Science (PLoS) 2025, Vol. 20, (3)
Bovinder Ylitalo, Erik; Vidman, Linda; Harlid, Sophia; et al.
A proteogenomic analysis of the adiposity colorectal cancer relationship identifies GREM1 as a probable mediator
International Journal of Epidemiology, Oxford University Press 2025, Vol. 54, (1)
Lee, Matthew A.; Hatcher, Charlie A.; Hazelwood, Emma; et al.
Functional variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are associated with increased risk of colorectal cancer
Human Molecular Genetics, Oxford University Press 2025, Vol. 34, (7) : 617-625
Prizment, Anna; Standafer, Abby; Qu, Conghui; et al.
Cohort profile: the Northern Sweden health and disease study (NSHDS)
International Journal of Epidemiology, Oxford University Press 2025, Vol. 54, (1)
Späth, Florentin; Wennberg, Patrik; Johansson, Robert; et al.
Folate intake and colorectal cancer risk according to genetic subtypes defined by targeted tumor sequencing
American Journal of Clinical Nutrition, Elsevier 2024, Vol. 120, (3) : 664-673
Aglago, Elom K.; Qu, Conghui; Harlid, Sophia; et al.
Dietary patterns, untargeted metabolite profiles and their association with colorectal cancer risk
Scientific Reports, Springer Nature 2024, Vol. 14, (1)
Bodén, Stina; Zheng, Rui; Ribbenstedt, Anton; et al.
Identification of potential mediators of the relationship between body mass index and colorectal cancer: a Mendelian randomization analysis
International Journal of Epidemiology, Oxford University Press 2024, Vol. 53, (3)
Bouras, Emmanouil; Gill, Dipender; Zuber, Verena; et al.
Fine-mapping analysis including over 254 000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes
Nature Communications, Springer Nature 2024, Vol. 15, (1)
Chen, Zhishan; Guo, Xingyi; Tao, Ran; et al.
Cohort profile: the Obesity and Disease Development Sweden (ODDS) study, a pooled cohort
BMJ Open, BMJ Publishing Group Ltd 2024, Vol. 14, (7)
da Silva, Marisa; Fritz, Josef; Mboya, Innocent B.; et al.
Two genome-wide interaction loci modify the association of nonsteroidal anti-inflammatory drugs with colorectal cancer
Science Advances, American Association for the Advancement of Science (AAAS) 2024, Vol. 10, (22)
Drew, David A.; Kim, Andre E.; Lin, Yi; et al.
Opposing roles by KRAS and BRAF mutation on immune cell infiltration in colorectal cancer: possible implications for immunotherapy
British Journal of Cancer, Springer Nature 2024, Vol. 130
Edin, Sofia; Gylling, Björn; Li, Xingru; et al.
Association between pre-diagnostic circulating lipid metabolites and colorectal cancer risk: a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC)
EBioMedicine, Elsevier 2024, Vol. 101
Harewood, Rhea; Rothwell, Joseph A.; Bešević, Jelena; et al.
Plasma ghrelin and risks of sex-specific, site-specific, and early-onset colorectal cancer: a Mendelian randomization analysis
Cancer Epidemiology, Biomarkers and Prevention, American Association For Cancer Research (AACR) 2024, Vol. 33, (12) : 1727-1732
Hazelwood, Emma; Lopez Manzano, Catalina; Vincent, Emma E.; et al.
Genome-wide association studies and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer
Annals of Oncology, Elsevier 2024, Vol. 35, (6) : 523-536
Laskar, R.S.; Qu, C.; Huyghe, J.R.; et al.
Prior antibiotics exposure is associated with an elevated risk of surgical site infections, including anastomotic leakage, after colon cancer but not rectal cancer surgery: A register-based study of 38,839 patients
International Journal of Cancer
Lu, Sai San Moon; Rutegård, Martin; Häggström, Christel; et al.
Body size and risk of colorectal cancer molecular defined subtypes and pathways: mendelian randomization analyses
EBioMedicine, Elsevier 2024, Vol. 101
Papadimitriou, Nikos; Qu, Conghui; Harrison, Tabitha A.; et al.
Sex- and site-specific associations of circulating lipocalin 2 and incident colorectal cancer: results from the EPIC cohort
International Journal of Cancer, John Wiley & Sons 2024, Vol. 156, (5)
Reichmann, Robin; Nimptsch, Katharina; Pischon, Tobias; et al.
Allometric versus traditional body-shape indices and risk of colorectal cancer: a Mendelian randomization analysis
International Journal of Obesity, Springer Nature 2024, Vol. 48 : 709-716
Rontogianni, Marina O.; Bouras, Emmanouil; Aglago, Elom Kouassivi; et al.
Body mass index and risk of over 100 cancer forms and subtypes in 4.1 million individuals in Sweden: the obesity and disease development Sweden (ODDS) pooled cohort study
The Lancet Regional Health: Europe, Elsevier 2024, Vol. 45
Sun, Ming; da Silva, Marisa; Bjørge, Tone; et al.
Epidemiologic factors in relation to colorectal cancer risk and survival by genotoxic colibactin mutational signature
Cancer Epidemiology, Biomarkers and Prevention, American Association For Cancer Research (AACR) 2024, Vol. 33, (4) : 534-546
Thomas, Claire E.; Georgeson, Peter; Qu, Conghui; et al.
Characterization of additive gene–environment interactions for colorectal cancer risk
Epidemiology, Wolters Kluwer 2024, Vol. 36, (1) : 126-138
Thomas, Claire E.; Lin, Yi; Kim, Michelle; et al.
Genetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk
British Journal of Cancer, Springer Nature 2024, Vol. 130, (10) : 1687-1696
Tian, Yu; Lin, Yi; Qu, Conghui; et al.
Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study
British Journal of Cancer, Springer Nature 2024, Vol. 130 : 114-124
Watts, Eleanor L.; Gonzales, Tomas I.; Strain, Tessa; et al.
Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study
British Journal of Cancer, Springer Nature 2023, Vol. 128 : 1529-1540
Aglago, Elom K.; Cross, Amanda J.; Riboli, Elio; et al.
A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk
Cancer Research, American Association For Cancer Research (AACR) 2023, Vol. 83, (15) : 2572-2583
Aglago, Elom K.; Kim, Andre; Lin, Yi; et al.
Plasma concentrations of gut hormones acyl ghrelin and peptide YY and subsequent risk of colorectal cancer and molecular tumor subtypes
Cancer Prevention Research, American Association for Cancer Research 2023, Vol. 16, (2) : 75-87
Bodén, Stina; Harbs, Justin; Sundkvist, Anneli; et al.
Genome-wide interaction analysis of folate for colorectal cancer risk
American Journal of Clinical Nutrition, Elsevier 2023, Vol. 118, (5) : 881-891
Bouras, Emmanouil; Kim, Andre E.; Lin, Yi; et al.
Genome-wide interaction study with smoking for colorectal cancer risk identifies novel genetic loci related to tumor suppression, inflammation, and immune response
Cancer Epidemiology, Biomarkers and Prevention, American association for cancer research 2023, Vol. 32, (3) : 315-328
Carreras-Torres, Robert; Kim, Andre E.; Lin, Yi; et al.
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
Nature Genetics, Nature Publishing Group 2023, Vol. 55 : 89-99
Fernandez-Rozadilla, Ceres; Timofeeva, Maria; Chen, Zhishan; et al.
An epigenome-wide analysis of sex hormone levels and DNA methylation in male blood samples
Epigenetics, Taylor & Francis Group 2023, Vol. 18, (1)
Harbs, Justin; Rinaldi, Sabina; Keski-Rahkonen, Pekka; et al.
Prediagnostic serum calcium concentrations and risk of colorectal cancer development in 2 large European prospective cohorts
American Journal of Clinical Nutrition, Elsevier 2023, Vol. 117, (1) : 33-45
Karavasiloglou, Nena; Hughes, David J.; Murphy, Neil; et al.
Prediagnostic prescription antibiotics use and survival in patients with colorectal cancer: a swedish national register-based study
Cancer Epidemiology, Biomarkers and Prevention, American Association For Cancer Research (AACR) 2023, Vol. 32, (10) : 1391-1401
Lu, Sai San Moon; Rutegård, Martin; Ahmed, Maghfoor; et al.
Body mass index and molecular subtypes of colorectal cancer
Journal of the National Cancer Institute, Oxford University Press 2023, Vol. 115, (2) : 165-173
Murphy, Neil; Newton, Christina C.; Song, Mingyang; et al.
Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer
BMC Medicine, BioMed Central (BMC) 2023, Vol. 21, (1)
Nimptsch, Katharina; Aleksandrova, Krasimira; Pham, Thu Thi; et al.
Association of pre-diagnostic physical exercise and peri-diagnostic body composition with mortality in non-metastatic colorectal cancer
International Journal of Colorectal Disease, Springer Nature 2023, Vol. 38, (1)
Renman, David; van Guelpen, Bethany; Anderson, Fredrick; et al.
Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts
BMC Medicine, BioMed Central (BMC) 2023, Vol. 21, (1)
Rothwell, Joseph A.; Bešević, Jelena; Dimou, Niki; et al.
Validation of a genetic-enhanced risk prediction model for colorectal cancer in a large community-based cohort
Cancer Epidemiology, Biomarkers and Prevention, American association for cancer research 2023, Vol. 32, (3) : 353-362
Su, Yu-Ru; Sakoda, Lori C.; Jeon, Jihyoun; et al.
Metabolically (un)healthy obesity and risk of obesity-related cancers: a pooled study
Journal of the National Cancer Institute, Oxford University Press 2023, Vol. 115, (4) : 456-467
Sun, Ming; Fritz, Josef; Häggström, Christel; et al.
CTH G1208T and MTHFR A1298C polymorphisms are associated with a higher risk of a first myocardial infarction with fatal outcome among women
Drug Metabolism and Personalized Therapy, De Gruyter Open 2023, Vol. 38, (1) : 57-63
Söderström, Elisabet; Andersson, Jonas; Söderberg, Stefan; et al.
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations
Nature Communications, Springer Nature 2023, Vol. 14, (1)
Thomas, Minta; Su, Yu-Ru; Rosenthal, Elisabeth A.; et al.
Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases
Journal of gastroenterology, Springer 2023, Vol. 58 : 229-245
Ugai, Tomotaka; Akimoto, Naohiko; Haruki, Koichiro; et al.
Molecular characteristics of early-onset colorectal cancer according to detailed anatomical locations: comparison with later-onset cases
American Journal of Gastroenterology, Wolters Kluwer 2023, Vol. 118, (4) : 712-726
Ugai, Tomotaka; Haruki, Koichiro; Harrison, Tabitha A.; et al.
Untargeted plasma metabolomics and risk of colorectal cancer: an analysis nested within a large-scale prospective cohort
Cancer & Metabolism, BioMed Central (BMC) 2023, Vol. 11, (1)
Vidman, Linda; Zheng, Rui; Bodén, Stina; et al.
Dietary fatty acids and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition
BMC Cancer, BioMed Central (BMC) 2023, Vol. 23, (1)
Yammine, S.G.; Huybrechts, I.; Biessy, C.; et al.
Work-Related Stress Was Not Associated with Increased Cancer Risk in a Population-Based Cohort Setting
Cancer Epidemiology, Biomarkers and Prevention, American Association for Cancer Research 2022, Vol. 31, (1) : 51-57
Hadrévi, Jenny; Myte, Robin; Olsson, Tommy; et al.
Circulating Sex Hormone Levels and Colon Cancer Risk in Men: A Nested Case–Control Study and Meta-Analysis
Cancer Epidemiology, Biomarkers and Prevention, American Association for Cancer Research 2022, Vol. 31, (4) : 793-803
Harbs, Justin; Rinaldi, Sabina; Gicquiau, Audrey; et al.
Diabetes mellitus in relation to colorectal tumor molecular subtypes: a pooled analysis of more than 9000 cases
International Journal of Cancer, John Wiley & Sons 2022, Vol. 151, (3) : 348-360
Harlid, Sophia; van Guelpen, Bethany; Qu, Conghui; et al.
Cancer worry distribution and willingness to undergo colonoscopy at three levels of hypothetical cancer risk - a population-based survey in Sweden
Cancers, MDPI 2022, Vol. 14, (4)
Hawranek, Carolina; Maxon, Johan; Andersson, Andreas; et al.
Beyond GWAS of colorectal cancer: putative causal variant for the 10q24.2 region
Cancer Epidemiology, Biomarkers and Prevention, American Association For Cancer Research (AACR) 2022, Vol. 31, (5) : 1077-1089
Jordahl, Kristina M.; Shcherbina, Anna; Harlid, Sophia; et al.
Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival
Scientific Reports, Nature Publishing Group 2022, Vol. 12, (1)
Labadie, Julia D.; Savas, Sevtap; Harrison, Tabitha A.; et al.
Visa publikationer i DiVA

Forskargrupper

Forskningsledare
Bethany van Guelpen Lab
Gruppmedlem
Arktisk kost, hälsa och hållbarhet

Forskningsprojekt

1 januari 2022 till 31 december 2024
Studier av uppkomst och riskprediktion av tjock- och ändtarmscancer i syfte att förbättra prevention
1 juli 2021 till 1 januari 2041
Kohortbeskrivningsprojektet
1 januari 2014 till 26 november 2030
Kostens roll i inflammationsrelaterade sjukdomar