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Anna Fahlgren
Vetenskaplig meritering:
Docent
Kontakt
E-post
anna.fahlgren@umu.se
Telefon
090-786 96 87
Verksam vid
Anknytning
Utbildningsledare vid
Kansliet för medicin
Enhet: Området för utbildning, forskning och kommunikation
Plats
Förvaltningshuset, Plan 7
Umeå universitet, 901 87 Umeå
Anknytning
Anknuten som övrig/annan befattning till
Institutionen för molekylärbiologi
Plats
6K och 6L, Sjukhusområdet
Umeå universitet, 901 87 Umeå
Publikationer
Publikationer
Forskning
Forskning
2024
A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection
Nature Communications
, Springer Nature 2024, Vol. 15, (1)
von Beek, Christopher; Fahlgren, Anna; Geiser, Petra; et al.
2021
Spatiotemporal Variations in Growth Rate and Virulence Plasmid Copy Number during Yersinia pseudotuberculosis Infection
Infection and Immunity
, American Society for Microbiology 2021, Vol. 89, (4)
Schneiders, Stephan; Hechard, Tifaine; Edgren, Tomas; et al.
2020
Genome-Scale Mapping Reveals Complex Regulatory Activities of RpoN in
Yersinia pseudotuberculosis
mSystem
, Vol. 5, (6)
Mahmud, A. K. M. Firoj; Nilsson, Kristina; Fahlgren, Anna; et al.
2019
Accumulation of virulence-associated proteins in
Campylobacter jejuni
Outer Membrane Vesicles at human body temperature
Journal of Proteomics
, Vol. 195 : 33-40
Taheri, Nayyer; Fällman, Maria; Wai, Sun Nyunt; et al.
2018
Campylobacter jejuni bile exposure influences outer membrane vesicles protein content and bacterial interaction with epithelial cells
Scientific Reports
, Nature Publishing Group 2018, Vol. 8
Taheri, Nayyer; Mahmud, A K M Firoj; Sandblad, Linda; et al.
2017
The Tat substrate SufI is critical for the ability of
Yersinia pseudotuberculosis
to cause systemic infection
Infection and Immunity
, Vol. 85, (4)
Avican, Ummehan; Doruk, Tugrul; Östberg, Yngve; et al.
2016
Yersinia pseudotuberculosis Blocks Neutrophil Degranulation
Infection and Immunity
, Vol. 84, (12) : 3369-3378
Taheri, Nayyer; Fahlgren, Anna; Fällman, Maria
2016
Increased plasmid copy number is essential for Yersinia T3SS function and virulence
Science
, Vol. 353, (6298) : 492-495
Wang, He; Avican, Kemal; Fahlgren, Anna; et al.
2015
Reprogramming of Yersinia from Virulent to Persistent Mode Revealed by Complex In Vivo RNA-seq Analysis
PLoS Pathogens
, Vol. 11, (1)
Avican, Kemal; Fahlgren, Anna; Huss, Mikael; et al.
2014
Colonization of cecum is important for development of persistent infection by
Yersinia pseudotuberculosis
Infection and Immunity
, American Society for Microbiology 2014, Vol. 82, (8) : 3471-3482
Fahlgren, Anna; Avican, Kemal; Westermark, Linda; et al.
2014
Maladjusted Host Immune Responses Induce Experimental Cerebral Malaria-Like Pathology in a Murine Borrelia and Plasmodium Co-Infection Model
PLOS ONE
, PLOS ONE 2014, Vol. 9, (7)
Normark, Johan; Nelson, Maria; Engström, Patrik; et al.
2014
Yersinia pseudotuberculosis Efficiently Escapes Polymorphonuclear Neutrophils during Early Infection
Infection and Immunity
, Vol. 82, (3) : 1181-1191
Westermark, Linda; Fahlgren, Anna; Fällman, Maria
2013
Metabolic profiling for detection of staphylococcus aureus infection and antibiotic resistance
PLOS ONE
, Vol. 8, (2)
Antti, Henrik; Fahlgren, Anna; Näsström, Elin; et al.
2013
Type III secretion translocon assemblies that attenuate Yersinia virulence
Cellular Microbiology
, Wiley-Blackwell 2013, Vol. 15, (7) : 1088-1110
Costa, Tiago; Amer, Ayad; Farag, Salah; et al.
2013
Role of YopK in Yersinia pseudotuberculosis Resistance Against Polymorphonuclear Leukocyte Defense
Infection and Immunity
, Vol. 81, (1) : 11-22
Thorslund, Sara E; Ermert, David; Fahlgren, Anna; et al.
2012
Coiled-coils in the YopD translocator family: A predicted structure unique to the YopD N-terminus contributes to full virulence of
Yersinia pseudotuberculosis
Infection, Genetics and Evolution
, Elsevier 2012, Vol. 12, (8) : 1729-1742
Costa, Tiago R. D.; Amer, Ayad A. A.; Fällman, Maria; et al.
2012
Lipopolysaccharide O-Antigen Prevents Phagocytosis of
Vibrio anguillarum
by Rainbow Trout (
Oncorhynchus mykiss
) Skin Epithelial Cells
PLOS ONE
, San Francisco: Public Library of Science 2012, Vol. 7, (5) : e37678-
Lindell, Kristoffer; Fahlgren, Anna; Hjerde, Erik; et al.
2012
Immune response to diphtheria toxin-mediated depletion complicates the use of the CD11c-DTRtg model for studies of bacterial gastrointestinal infections
Immunology
, Vol. 137, (S1) : 271-271
Westermark, Linda; Fahlgren, Anna; Fällman, Maria
2012
Immune response to diphtheria toxin-mediated depletion complicates the use of the CD11c-DTR(tg) model for studies of bacterial gastrointestinal infections
Microbial Pathogenesis
, Vol. 53, (3-4) : 154-161
Westermark, Linda; Fahlgren, Anna; Fällman, Maria
2011
Translocation of surface-localized effectors in type III secretion
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 108, (4) : 1639-1644
Akopyan, Karen; Edgren, Tomas; Wang-Edgren, Helen; et al.
2011
Chronic colitis induces expression of β-defensins in murine intestinal epithelial cells
Clinical and Experimental Immunology
, Vol. 163, (1) : 123-130
Rahman, Arman; Fahlgren, Anna; Sundstedt, C; et al.
2009
Cell type-specific effects of Yersinia pseudotuberculosis virulence effectors
Cellular Microbiology
, Vol. 11, (12) : 1750-1767
Fahlgren, Anna; Westermark, Linda; Akopyan, Karen; et al.
2009
The membrane localization domain is required for intracellular localization and autoregulation of YopE in Yersinia pseudotuberculosis.
Infection and Immunity
, American Society for Microbiology 2009, Vol. 77, (11) : 4740-4749
Isaksson, Elin L; Aili, Margareta; Fahlgren, Anna; et al.
2007
Beta-defensin production by human colonic plasma cells: a new look at plasma cells in ulcerative colitis
Inflammatory Bowel Diseases
, Vol. 13, (7) : 847-855
Rahman, Arman; Fahlgren, Anna; Sitohy, Basel; et al.
2004
β
-Defensin-3 and -4 in intestinal epithelial cells display increased mRNA expression in ulcerative colitis
Clinical and Experimental Immunology
, Oxford: Blackwell Publishing 2004, Vol. 137, (2) : 379-385
Fahlgren, Anna; Hammarström, Sten; Danielsson, Åke; et al.
2004
Presence of bacteria and innate immunity of intestinal epithelium in childhood celiac disease
American Journal of Gastroenterology
, Vol. 99, (5) : 894-904
Forsberg, Göte; Fahlgren, Anna; Hörstedt, Per; et al.
2003
Defence capabilities of human intestinal epithelial cells
Umeå University medical dissertations
, 862
Fahlgren, Anna
2003
Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence.
Scandinavian Journal of Immunology
, Vol. 58, (6) : 628-41
Fahlgren, Anna; Baranov, Vladimir; Frängsmyr, L; et al.
2003
Interferon-γ tempers the expression of carcinoembryonic antigen (CEA) family molecules – a role in innate colonic defence.
Scandinavian Journal of Immunology
, Vol. 58, (6) : 628-641
Fahlgren, Anna; Baranov, Vladimir; Frängsmyr, Lars; et al.
Malaria-enhanced Neutrophil Dependent Clearance of
S. pneumoniae
in an
in vivo
Co-infection Model
Nelson, Maria; Niemic, Maria Joanna; Fahlgren, Anna; et al.
Campylobacter jejuni outer membrane vesicles activate inflammasome without inducing cell death in immune cells
Taheri, Nayyer; Wai, Sun Nyunt; Fällman, Maria; et al.
Role of YopK in
Yersinia
resistance against polymorphonuclear leukocyte defense
Thorslund, Sara E; Ermert, D; Fahlgren, Anna; et al.
Yersinia pseudotuberculosis
efficiently avoids polymorphonuclear neutrophils during early infection
Westermark, Linda; Fahlgren, Anna; Fällman, Maria
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