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Andrea Puhar
Vetenskaplig meritering:
Docent
Kontakt
E-post
andrea.puhar@umu.se
Telefon
090-785 33 51
Verksam vid
Anknytning
Gästuniversitetslektor vid
Institutionen för molekylärbiologi
Enhet: Grupp Andrea Puhar
Plats
6K och 6L, Sjukhusområdet
Umeå universitet, 901 87 Umeå
Publikationer
Publikationer
Forskning
Forskning
Omnämnanden
Omnämnanden
2023
CRISPR-cas-guided mutagenesis of chromosome and virulence plasmid in
Shigella flexneri
by cytosine base editing
mSystems
, American Society for Microbiology 2023, Vol. 8, (1)
Sharma, Atin; Omer Aden, Ruqiya; Puhar, Andrea; et al.
2023
At-home sampling to meet geographical challenges for serological assessment of SARS-CoV-2 exposure in a rural region of northern Sweden, March to May 2021: a retrospective cohort study
Eurosurveillance
, European Centre for Disease Control and Prevention (ECDC) 2023, Vol. 28, (13)
Wigren, Julia; Vikström, Linnea; Rosendal, Ebba; et al.
2022
RpuS/R is a novel two-component signal transduction system that regulates the expression of the pyruvate symporter MctP in S
inorhizobium fredii
NGR234
Frontiers in Microbiology
, Frontiers Media S.A. 2022, Vol. 13
Ramos, Ana Laura; Aquino, Maria; García, Gema; et al.
2022
Infection-induced membrane ruffling initiates danger and immune signaling via the mechanosensor PIEZO1
Cell Reports
, Elsevier 2022, Vol. 40, (6)
Tadala, Lalitha; Langenbach, Dorothee; Dannborg, Mirjam; et al.
2021
Vibrio cholerae
cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy
Journal of Cell Science
, The Company of Biologists 2021, Vol. 134, (5)
Corkery, Dale; Nadeem, Aftab; Aung, Kyaw Min; et al.
2021
Generation of plasma cells and CD27
-
IgD
-
B cells during hantavirus infection is associated with distinct pathological findings
Clinical & Translational Immunology (CTI)
, John Wiley & Sons 2021, Vol. 10
Kerkman, Priscilla; Dernstedt, Andy; Tadala, Lalitha; et al.
2020
Whole-Genome Identification of Transcriptional Start Sites by Differential RNA-seq in Bacteria
Bio-protocol
, Bio-protocol 2020, Vol. 10, (18)
Cervantes-Rivera, Ramón; Puhar, Andrea
2020
Complete genome sequence and annotation of the laboratory reference strain
Shigella flexneri
serotype 5a M90T and genome-wide transcriptional start site determination
BMC Genomics
, Springer Nature 2020, Vol. 21, (1)
Cervantes-Rivera, Ramón; Tronnet, Sophie; Puhar, Andrea
2019
Plaque Assay to Determine Invasion and Intercellular Dissemination of Shigella flexneri in TC7 Human Intestinal Epithelial Cells
Bio-protocol
, Bio-Protocol 2019, Vol. 9, (13)
Sharma, Atin; Puhar, Andrea
2019
Gentamicin Protection Assay to Determine the Number of Intracellular Bacteria during Infection of Human TC7 Intestinal Epithelial Cells by Shigella flexneri
Bio-protocol
, Bio-Protocol 2019, Vol. 9, (13)
Sharma, Atin; Puhar, Andrea
2016
PI5P Triggers ICAM-1 Degradation in
Shigella
Infected Cells, Thus Dampening Immune Cell Recruitment
Cell Reports
, Cell Press 2016, Vol. 14, (4) : 750-759
Boal, Frédéric; Puhar, Andrea; Xuereb, Jean-Marie; et al.
2015
Distinct mutations led to inactivation of type 1 fimbriae expression in Shigella spp
PLOS ONE
, Vol. 10, (3)
Bravo, Verónica; Puhar, Andrea; Sansonetti, Philippe; et al.
2014
Type III secretion system
Current Biology
, Vol. 24, (17) : R784-R791
Puhar, Andrea; Sansonetti, Philippe J
2014
Induction of Connexin-hemichannel Opening
Bio-protocol
, Vol. 4, (17)
Puhar, Andrea; Sansonetti, Philippe J.
2014
Dye-uptake Experiment through Connexin Hemichannels
Bio-protocol
, Vol. 4, (17)
Puhar, Andrea; Sansonetti, Philippe J.
2013
A Shigella effector dampens inflammation by regulating epithelial release of danger signal ATP through production of the lipid mediator PtdIns5P
Immunity
, Vol. 39, (6) : 1121-1131
Puhar, Andrea; Tronchère, Hélène; Payrastre, Bernard; et al.
2012
Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers
EMBO Molecular Medicine
, Vol. 4, (9) : 866-881
Teo, Ian; Toms, Steve M.; Marteyn, Benoit; et al.
2011
The Shigella flexneri type three secretion system effector IpgD inhibits T cell migration by manipulating host phosphoinositide metabolism
Cell Host and Microbe
, Vol. 9, (4) : 263-272
Konradt, Christoph; Frigimelica, Elisabetta; Nothelfer, Katharina; et al.
2011
Haemolysin II is a Bacillus cereus virulence factor that induces apoptosis of macrophages
Cellular Microbiology
, Vol. 13, (1) : 92-108
Tran, Seav-Ly; Guillemet, Elisabeth; Ngo-Camus, Maud; et al.
2011
Trypan blue dye enters viable cells incubated with the pore-forming toxin HlyII of Bacillus cereus
PLOS ONE
, Vol. 6, (9)
Tran, Seav-Ly; Puhar, Andrea; Ngo-Camus, Maud; et al.
2008
cAMP imaging of cells treated with pertussis toxin, cholera toxin, and anthrax edema toxin
Biochemical and Biophysical Research Communications - BBRC
, Vol. 376, (2) : 429-433
Dal Molin, Federica; Zornetta, Irene; Puhar, Andrea; et al.
2008
NADH oxidation drives respiratory Na+ transport in mitochondria from Yarrowia lipolytica
Archives of Microbiology
, Vol. 190, (4) : 471-480
Lin, Po-Chi; Puhar, Andrea; Steuber, Julia
2008
Anthrax edema toxin modulates PKA- and CREB-dependent signaling in two phases
PLOS ONE
, Vol. 3, (10)
Puhar, Andrea; Dal Molin, Federica; Horvath, Stéphanie; et al.
2007
The concerted action of the Helicobacter pylori cytotoxin VacA and of the v-ATPase proton pump induces swelling of isolated endosomes
Cellular Microbiology
, Vol. 9, (6) : 1481-1490
Genisset, Christophe; Puhar, Andrea; Calore, Federica; et al.
2007
Where and how do anthrax toxins exit endosomes to intoxicate host cells?
Trends in Microbiology
, Vol. 15, (11) : 477-482
Puhar, Andrea; Montecucco, Cesare
2005
A vertebrate-type ferredoxin domain in the Na+-translocating NADH dehydrogenase from Vibrio cholerae
Journal of Biological Chemistry
, Vol. 280, (24) : 22560-22563
Lin, Po-Chi; Puhar, Andrea; Türk, Karin; et al.
2004
Comparison of the pH-induced conformational change of different clostridial neurotoxins
Biochemical and Biophysical Research Communications - BBRC
, Vol. 319, (1) : 66-71
Puhar, Andrea; Johnson, E A; Rossetto, O; et al.
2004
NADH oxidation by the Na+-translocating NADH: quinone oxidoreductase from Vibrio cholerae
Journal of Biological Chemistry
, Vol. 279, (20) : 21349-21355
Türk, Karin; Puhar, Andrea; Neese, Frank; et al.
PIEZO1 activation during invasive infection triggers broad changes in the transcriptional landscape
Tadala, Lalitha; Cervantes-Rivera, Ramón; Puhar, Andrea
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Forskargrupper
Forskningsledare
Andrea Puhar
Forskningsprojekt
1 januari 2022 till 31 december 2024
Mekanism och inflammatorisk påverkan av extracellular ATP-signalering I tarmbakterier
Publicerad: 10 nov, 2022
50 miljoner kronor till ny forskning inom UCMR
Publicerad: 04 nov, 2022
73 miljoner till medicinsk forskning
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