Torbjörn Bäckström

0000-0002-0907-3535

Contact

torbjorn.c.backstrom@umu.se

+46 90 785 21 44

Works at

Affiliated as professor emeritus at Department of Clinical Sciences Section: Obstetrics and Gynecology

By 6M, 3 tr, NUS Umeå universitet, Klinisk vetenskap,Obstetrik och gynekologi, 901 85 Umeå

Allopregnanolone and its antagonist modulate neuroinflammation and neurological impairment

Neuroscience and Biobehavioral Reviews, Elsevier 2024, Vol. 161

Bäckström, Torbjörn; Doverskog, Magnus; Blackburn, Thomas P.; et al.

Extra-synaptic GABAA receptor potentiation and neurosteroid-induced learning deficits are inhibited by GR3027, a GABAA modulating steroid antagonist

Biomolecules, MDPI 2023, Vol. 13, (10)

Bengtsson, Sara K. S.; Sjöstedt, Jessica; Malinina, Evgenya; et al.

Isoallopregnanolone inhibits estrus cycle-dependent aggressive behavior

Biomolecules, MDPI 2023, Vol. 13, (6)

Bäckström, Torbjörn; Bengtsson, Sara K. S.; Sjöstedt, Jessica; et al.

Effects of hormones on seizure expression

Epilepsy: a comprehensive textbook, New York: Wolters Kluwer 2023 : 779-792

Bäckström, Torbjörn; Bäckström, David C; Joshi, Suchitra

The GABA system, a new target for medications against cognitive impairment—Associated with neuroactive steroids

Journal of Internal Medicine, John Wiley & Sons 2023, Vol. 294, (3) : 281-294

Bäckström, Torbjörn; Turkmen, Sahruh; Das, Roshni; et al.

Altered GABAA receptor function in women with endometriosis: a possible pain-related mechanism

Acta Obstetricia et Gynecologica Scandinavica, John Wiley & Sons 2023, Vol. 102, (10) : 1316-1322

Sandström, Anton; Bixo, Marie; Bäckström, Torbjörn; et al.

Menstruationscykelns reglering och grundläggande reproduktionsendokrinologi

Gynekologi, Lund: Studentlitteratur AB 2022 : 53-78

Bäckström, Torbjörn

Menstruationscykelbundna tillstånd

Gynekologi, Lund: Studentlitteratur AB 2022 : 89-96

Bäckström, Torbjörn

Menstruationscykelns fysiologi

Problemorienterad gynekologi och obstetrik, Stockholm: Liber 2022 : 20-27

Bäckström, Torbjörn

Premenstruella besvär

Problemorienterad gynekologi och obstetrik, Stockholm: Liber 2022 : 176-181

Bäckström, Torbjörn

Positive GABAA receptor modulating steroids and their antagonists: Implications for clinical treatments

Journal of neuroendocrinology (Print), John Wiley & Sons 2022, Vol. 34, (2)

Bäckström, Torbjörn; Das, Roshni; Bixo, Marie

Gynekologi

Lund: Studentlitteratur AB 2022

Bäckström, Torbjörn; Kjølhede, Preben; Landgren, Britt-Marie

Medroxyprogesterone acetate positively modulates specific GABAA-receptor subtypes - affecting memory and cognition

Psychoneuroendocrinology, Elsevier 2022, Vol. 141

Das, Roshni; Ragagnin, Gianna; Sjöstedt, Jessica; et al.

Golexanolone, a GABAA receptor modulating steroid antagonist, restores motor coordination and cognitive function in hyperammonemic rats by dual effects on peripheral inflammation and neuroinflammation

CNS Neuroscience & Therapeutics, John Wiley & Sons 2022, Vol. 28, (11) : 1861-1874

Mincheva, Gergana; Gimenez-Garzo, Carla; Izquierdo-Altarejos, Paula; et al.

Vaginal flytning och sexuellt överförda infektioner

Problemorienterad gynekologi och obstetrik, Stockholm: Liber 2022 : 111-115

Sjöberg, Inga; Bäckström, Torbjörn

Neurosteroid activation of gaba-a receptors: a potential treatment target for symptoms in primary biliary cholangitis?

Canadian journal of gastroenterology & hepatology, Hindawi Publishing Corporation 2022, Vol. 2022

Wetten, Aaron; Ogle, Laura; Mells, George; et al.

A randomized, double-blind study on efficacy and safety of sepranolone in premenstrual dysphoric disorder

Psychoneuroendocrinology, Vol. 133

Bäckström, Torbjörn; Ekberg, Karin; Lindén Hirschberg, Angelica; et al.

A pilot study of golexanolone, a new GABA-A receptor-modulating steroid antagonist, in patients with covert hepatic encephalopathy

Journal of Hepatology, Elsevier 2021, Vol. 75, (1) : 98-107

Montagnese, Sara; Lauridsen, Mette; Vilstrup, Hendrik; et al.

Neurosteroid involvement in threatened preterm labour

Endocrinology, Diabetes & Metabolism, Sussex: John Wiley & Sons 2021, Vol. 4, (2)

Turkmen, Sahruh; Bäckström, Torbjörn; Kangas Flodin, Yvonne; et al.

GABA-A receptor modulating steroids in acute and chronic stress; relevance for cognition and dementia?

Neurobiology of stress, Elsevier 2020, Vol. 12

Bengtsson, Sara; Bäckström, Torbjörn; Brinton, R.; et al.

Praktisk preventivmedelsguide

Bayer AB 2020

Bixo, Marie; Brynhildsen, Jan; Bäckström, Torbjörn; et al.

Isoallopregnanolone reduces tic-like behaviours in the D1CT-7 mouse model of Tourette syndrome

Journal of neuroendocrinology (Print), Blackwell Publishing 2020, Vol. 32, (1)

Cadeddu, Roberto; Bäckström, Torbjörn; Floris, Gabriele; et al.

Body fat percentage and CRP correlates with a composite score of vascular risk markers in healthy, young adults: The Lifestyle, Biomarkers, and Atherosclerosis (LBA) study

BMC Cardiovascular Disorders, BioMed Central 2020, Vol. 20

Pettersson-Pablo, Paul; Cao, Yang; Bäckström, Torbjörn; et al.

Effect of hysterectomy on pain in women with endometriosis: a population-based registry study

British Journal of Obstetrics and Gynecology, John Wiley & Sons 2020, Vol. 127, (13) : 1628-1635

Sandström, Anton; Bixo, Marie; Johansson, Maja; et al.

Changes in premenstrual symptoms in women starting or discontinuing use of oral contraceptives

Gynecological Endocrinology, Taylor & Francis Group 2019, Vol. 35, (5) : 422-426

Ekenros, Linda; Bäckström, Torbjörn; Hirschberg, Angelica Lindén; et al.

The additive effect of allopregnanolone on ghrelin's orexigenic effect in rats

Neuropeptides, Elsevier 2019, Vol. 76

Löfgren, Magnus; Holmberg, Ellinor; Bäckström, Torbjörn; et al.

Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age

Frontiers in Psychology, Frontiers Media S.A. 2019, Vol. 9

Poromaa, Inger Sundstrom; Comasco, Erika; Bäckström, Torbjörn; et al.

Effects of GABA active steroids in the female brain with a focus on the premenstrual dysphoric disorder

Journal of neuroendocrinology (Print), Vol. 30, (2)

Bixo, Marie; Johansson, Maja; Timby, Erika; et al.

Allopregnanolone involvement in feeding regulation, overeating and obesity

Frontiers in neuroendocrinology (Print), Academic Press 2018, Vol. 48 : 70-77

Holmberg, Ellinor; Sjöstedt, J.; Malinina, E.; et al.

GR3027 reversal of neurosteroid-induced, GABA-A receptor-mediated inhibition of human brain function: an allopregnanolone challenge study

Psychopharmacology, Springer 2018, Vol. 235, (5) : 1533-1543

Johansson, Maja; Månsson, Maria; Lins, Lars-Eric; et al.

Treatment of premenstrual dysphoric disorder with the GABA(A) receptor modulating steroid antagonist Sepranolone (UC1010)-A randomized controlled trial

Psychoneuroendocrinology, Vol. 80 : 46-55

Bixo, Marie; Ekberg, Karin; Poromaa, Inger Sundstrom; et al.

The relationship between weight gain during pregnancy and allopregnanolone levels: a longitudinal study

Endocrine Connections, Bioscientifica 2017, Vol. 6, (4) : 253-259

Lundqvist, Anette; Sandström, Herbert; Bäckström, Torbjörn

Follow-up after early medical abortion: comparing clinical assessment with self-assessment in a rural hospital in northern Norway

European Journal of Obstetrics, Gynecology, and Reproductive Biology, Elsevier 2017, Vol. 213 : 1-3

Mahlck, Carl-Gustav; Bäckström, Torbjörn

Long-term continuous allopregnanolone elevation causes memory decline and hippocampus shrinkage, in female wild-type B6 mice

Hormones and Behavior, Vol. 78 : 160-167

Bengtsson, Sara K S; Johansson, Maja; Bäckström, Torbjörn

GABAA receptor modulating steroid antagonists (GAMSA) are functional in vivo

Journal of Steroid Biochemistry and Molecular Biology, Elsevier 2016, Vol. 160, (SI) : 98-105

Johansson, Maja; Strömberg, Jessica; Ragagnin, Gianna; et al.

Women with PTSD have a changed sensitivity to GABA-A receptor active substances

Psychopharmacology, Vol. 233, (11) : 2025-2033

Tiihonen Möller, Anna; Bäckström, Torbjörn; Nyberg, Sigrid; et al.

Women with premenstrual dysphoric disorder have altered sensitivity to allopregnanolone over the menstrual cycle compared to controls — a pilot study

Psychopharmacology, Vol. 233, (11) : 2109-2117

Timby, Erika; Bäckström, Torbjörn; Nyberg, Sigrid; et al.

Roux-en-Y Gastric Bypass Surgery in Patients with Polycystic Ovary Syndrome and Metabolic Syndrome

Obesity Surgery, Vol. 26, (1) : 111-118

Turkmen, Sahruh; Ahangari, Alebtekin; Bäckström, Torbjörn

The author's reply: Blood allopregnanolone levels in women with polycystic ovary syndrome

Clinical Endocrinology, Vol. 85, (1) : 152-154

Turkmen, Sahruh; Bixo, Marie; Hedström, Helena; et al.

Acute intermittent porphyria symptoms during the menstrual cycle

Internal medicine journal (Print), Vol. 45, (7) : 725-731

Ahangari, Alebtekin; Bäckström, Torbjörn; Innala, Eva; et al.

Isoallopregnanolone antagonize allopregnanolone-induced effects on saccadic eye velocity and self-reported sedation in humans

Psychoneuroendocrinology, Vol. 52 : 22-31

Bengtsson, Sara K. S.; Nyberg, Sigrid; Hedström, Helena; et al.

GABA_A Receptor-Modulating Steroids in Relation to Women’s Behavioral Health

Current Psychiatry Reports, Vol. 17, (11)

Bäckström, Torbjörn; Bixo, Marie; Strömberg, Jessica

Women with polycystic ovary syndrome have elevated serum concentrations of and altered GABA _A receptor sensitivity to allopregnanolone

Clinical Endocrinology, John Wiley & Sons 2015, Vol. 83, (5) : 643-650

Hedström, Helena; Bäckström, Torbjörn; Bixo, Marie; et al.

Repeated allopregnanolone exposure induces weight gain in schedule fed rats on high fat diet

Physiology and Behavior, Elsevier 2015, Vol. 140 : 1-7

Holmberg, Ellinor; Johansson, Maja; Bäckström, Torbjörn; et al.

GR3027 antagonizes GABA(A) receptor-potentiating neurosteroids and restores spatial learning and motor coordination in rats with chronic hyperammonemia and hepatic encephalopathy

American Journal of Physiology - Gastrointestinal and Liver Physiology, American Physiological Society 2015, Vol. 309, (5) : G400-G409

Johansson, Maja; Agusti, Ana; Llansola, Marta; et al.

Svensk medicinsk forskning behöver inte mer styrning

Läkartidningen, Vol. 111, (22-23) : 980-981

Andersén, Peter; Bäckström, Torbjörn; Dahlquist, Gisela; et al.

Allopregnanolone and mood disorders

Progress in Neurobiology, Vol. 113 : 88-94

Bäckström, Torbjörn; Bixo, Marie; Johansson, Maja; et al.

Sexuality and androgens in women with cyclical mood changes and pre-menstrual syndrome

Acta Obstetricia et Gynecologica Scandinavica, Vol. 93, (3) : 248-255

Ekholm, Ulla-Britt; Turkmen, Sahruh; Hammarbäck, Stefan; et al.

Low Serum Allopregnanolone Is Associated with Symptoms of Depression in Late Pregnancy

Neuropsychobiology, Vol. 69, (3) : 147-153

Hellgren, Charlotte; Akerud, Helena; Skalkidou, Alkistis; et al.

Allopregnanolone preferentially induces energy-rich food intake in male Wistar rats

Physiological Reports, Wiley Periodicals Inc. 2014, Vol. 2, (12) : e12190-

Holmberg, Ellinor; Johansson, Maja; Bäckström, Torbjörn; et al.

View publications in DiVA

Research projects

6 April 2009 until 31 December 2009

Basis for sex and stress hormone induced mood symptoms and diseases