Tatiana Kan

Contact

tatiana.kan@umu.se

+46 90 785 67 95

Works at

Staff scientist at Department of Molecular Biology Section: Research group Yuri Schwartz

6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå

DNA elements tether canonical Polycomb Repressive Complex 1 to human genes

Nucleic Acids Research, Oxford University Press 2023, Vol. 51, (21) : 11613-11633

Barrasa, Juan I.; Kahn, Tatyana G.; Lundkvist, Moa J.; et al.

Topological screen identifies hundreds of Cp190- and CTCF-dependent Drosophila chromatin insulator elements

Science Advances, Vol. 9, (5)

Kahn, Tatyana G.; Savitsky, Mikhail; Kuong, Chikuan; et al.

Genetic Dissection Reveals the Role of Ash1 Domains in Counteracting Polycomb Repression

G3: Genes, Genomes, Genetics, The Genetics Society of America 2019, Vol. 9, (11) : 3801-3812

Dorafshan, Eshagh; Kahn, Tatyana G.; Glotov, Alexander; et al.

Ash1 counteracts Polycomb repression independent of histone H3 lysine 36 methylation

EMBO Reports, WILEY 2019, Vol. 20, (4)

Dorafshan, Eshagh; Kahn, Tatyana G.; Glotov, Alexander; et al.

PTE, a novel module to target Polycomb Repressive Complex 1 to the human cyclin D2 (CCND2) oncogene

Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2018, Vol. 293, (37) : 14342-14358

Cameron, Sarina R.; Nandi, Soumyadeep; Kahn, Tatyana G.; et al.

Hierarchical recruitment of Polycomb complexes revisited

Nucleus, Taylor & Francis Group 2017, Vol. 8, (5) : 496-505

Dorafshan, Eshagh; Kahn, Tatyana G.; Schwartz, Yuri B.

Interdependence of PRC1 and PRC2 for recruitment to Polycomb Response Elements

Nucleic Acids Research, Vol. 44, (21) : 10132-10149

Kahn, Tatyana G.; Dorafshan, Eshagh; Schultheis, Dorothea; et al.

Genome-wide activities of Polycomb complexes control pervasive transcription

Genome Research, Vol. 25, (8) : 1170-1181

Lee, Hun-Goo; Kahn, Tatyana G.; Simcox, Amanda; et al.

Combinatorial Interactions Are Required for the Efficient Recruitment of Pho Repressive Complex (PhoRC) to Polycomb Response Elements

PLOS Genetics, PLOS 2014, Vol. 10, (7) : e1004495-

Kahn, Tatyana G.; Stenberg, Per; Pirrotta, Vincenzo; et al.

Regulation of Polycomb group genes Psc and Su(z)2 in Drosophila melanogaster

Mechanisms of Development, Elsevier Ireland Ltd. 2012, Vol. 128, (11-12) : 536-547

Park, Sung Yeon; Schwartz, Yuri B; Kahn, Tatyana G; et al.

Alternative Epigenetic Chromatin States of Polycomb Target Genes

PLoS Genetics, Public Library of Science 2010, Vol. 6, (1) : e1000805-

Schwartz, Yuri B.; Kahn, Tatyana G.; Stenberg, Per; et al.

[Polycomb and trithorax control genome expression by determining the alternative epigenetic states of chromatin for key developmental regulators].

Journal Genetika, Vol. 46, (10) : 1413-1416

Shwartz, Yuri B; Kahn, Tatiana G; Pirrotta, V

Regulation of the Drosophila Enhancer of split and invected-engrailed gene complexes by sister chromatid cohesion proteins

PloS one, Vol. 4, (7) : e6202-

Schaaf, Cheri A; Misulovin, Ziva; Sahota, Gurmukh; et al.

Long-distance interactions between regulatory elements are suppressed at the end of a terminally deficient chromosome in Drosophila melanogaster.

Chromosoma, Vol. 117, (1) : 41-50

Melnikova, Larisa; Biryukova, Inna; Kan, Tatyana; et al.

Polycomb complexes and the propagation of the methylation mark at the Drosophila ubx gene

Journal of Biological Chemistry, Vol. 281, (39) : 29064-29075

Kahn, Tatyana G; Schwartz, Yuri B; Dellino, Gaetano I; et al.

Genome-wide analysis of Polycomb targets in Drosophila melanogaster

Nature Genetics, Vol. 38, (6) : 700-705

Schwartz, Yuri B; Kahn, Tatyana G; Nix, David A; et al.

Characteristic low density and shear sensitivity of cross-linked chromatin containing polycomb complexes

Molecular and Cellular Biology, Vol. 25, (1) : 432-439

Schwartz, Yuri B; Kahn, Tatyana G; Pirrotta, Vincenzo

Polycomb silencing mechanisms in Drosophila

Cold Spring Harbor Symposia on Quantitative Biology, Vol. 69 : 301-308

Schwartz, Yuri B; Kahn, Tatiana G; Dellino, G I; et al.

Transvection at the end of the truncated chromosome in Drosophila melanogaster

Genetics, Vol. 163, (4) : 1375-1387

Savitsky, Mikhail; Kahn, Tatyana; Pomerantseva, Ekaterina; et al.

Attachment of HeT-A sequences to chromosomal termini in Drosophila melanogaster may occur by different mechanisms

Molecular and Cellular Biology, Vol. 20, (20) : 7634-7642

Kahn, Tatiana; Savitsky, Mikhail; Georgiev, Pavel

hobo Induced rearrangements in the yellow locus influence the insulation effect of the gypsy su(Hw)-binding region in Drosophila melanogaster

Genetics, Genetics Society of America 1998, Vol. 149, (3) : 1393-1405

Gause, Maria; Hovhannisyan, Hayk; Kan, Tatiana; et al.

Functional dissection of Drosophila Ash1 domains

Dorafshan, Eshagh; Kahn, Tatyana G.; Glotov, Alexander; et al.

Does Ash1 counteract Polycomb repression by methylating H3K36?

Dorafshan, Eshagh; Kahn, Tatyana G.; Glotov, Alexander; et al.

View publications in DiVA

Research groups

Group member

Yuri Schwartz lab

Research projects

1 January 2022 until 31 December 2025

Epigenetic regulation by Polycomb-Trithorax system: leaving the mark on histones and other proteins