Sofia Edin

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Works at

Staff scientist at Department of Medical Biosciences Section: Pathology

By 6M, Sjukhusområdet Umeå universitet, 901 85 Umeå

Opposing roles by KRAS and BRAF mutation on immune cell infiltration in colorectal cancer: possible implications for immunotherapy

British Journal of Cancer, Springer Nature 2024, Vol. 130

Edin, Sofia; Gylling, Björn; Li, Xingru; et al.

Sporadic deficient mismatch repair in colorectal cancer increases the risk for non-colorectal malignancy: a European multicenter cohort study

Journal of Surgical Oncology, John Wiley & Sons 2024, Vol. 129, (7) : 1295-1304

Gkekas, Ioannis; Novotny, Jan; Kaprio, Tuomas; et al.

Prognostic genome and transcriptome signatures in colorectal cancers

Nature, Springer Nature 2024, Vol. 633 : 137-146

Nunes, Luís; Li, Fuqiang; Wu, Meizhen; et al.

Porphyromonas gingivalis in colorectal cancer and its association to patient prognosis

Journal of Cancer, Ivyspring International Publisher 2023, Vol. 14, (9) : 1479-1485

Kerdreux, Maïwenn; Edin, Sofia; Löwenmark, Thyra; et al.

Parvimonas micra is associated with tumour immune profiles in molecular subtypes of colorectal cancer

Cancer Immunology and Immunotherapy, Springer 2022, Vol. 71 : 2565-2575

Löwenmark, Thyra; Li, Xingru; Löfgren Burström, Anna; et al.

Tumour colonisation of Parvimonas micra is associated with decreased survival in colorectal cancer patients

Cancers, Vol. 14, (23)

Löwenmark, Thyra; Löfgren Burström, Anna; Zingmark, Carl; et al.

Colon cancer patients with mismatch repair deficiency are more likely to present as acute surgical cases

European Journal of Cancer, Elsevier 2021, Vol. 157 : 1-9

Gkekas, Ioannis; Novotny, Jan; Kaprio, Tuomas; et al.

A modified protein marker panel to identify four consensus molecular subtypes in colorectal cancer using immunohistochemistry

Pathology, Research and Practice, Elsevier 2021, Vol. 220

Li, Xingru; Larsson, Pär; Ljuslinder, Ingrid; et al.

Association between local immune cell infiltration, mismatch repair status and systemic inflammatory response in colorectal cancer

Journal of Translational Medicine, BioMed Central 2020, Vol. 18

Gunnarsson, Ulf; Strigård, Karin; Edin, Sofia; et al.

Ex Vivo Organoid Cultures Reveal the Importance of the Tumor Microenvironment for Maintenance of Colorectal Cancer Stem Cells

Cancers, MDPI 2020, Vol. 12, (4)

Li, Xingru; Larsson, Pär; Ljuslinder, Ingrid; et al.

A Detailed Flow Cytometric Analysis of Immune Activity Profiles in Molecular Subtypes of Colorectal Cancer

Cancers, MDPI 2020, Vol. 12, (11)

Li, Xingru; Ling, Agnes; Kellgren, Therese G.; et al.

Parvimonas micra as a putative non-invasive faecal biomarker for colorectal cancer

Scientific Reports, Nature Publishing Group 2020, Vol. 10, (1)

Löwenmark, Thyra; Löfgren Burström, Anna; Zingmark, Carl; et al.

The Prognostic Importance of CD20⁺ B lymphocytes in Colorectal Cancer and the Relation to Other Immune Cell subsets

Scientific Reports, Nature Publishing Group 2019, Vol. 9, (1)

Edin, Sofia; Kaprio, Tuomas; Hagström, Jaana; et al.

The Prognostic Importance of CD20⁺ B lymphocytes in Colorectal Cancer and the Relation to Other Immune Cell subsets

Scientific Reports, Nature Publishing Group 2019, Vol. 9

Edin, Sofia; Kaprio, Tuomas; Hagström, Jaana; et al.

The Combined Value of Faecal Haemoglobin andCalprotectin in Diagnosis of Colorectal Cancer inSymptomatic Patients Referred to Colonoscopy

Academic Journal of Gastroenterology & Hepatology (AJGH), San Fransisco: Iris Publishers 2019, Vol. 1, (3) : 1-7

Eklöf, Vincy; Lundgren, David; Karling, Pontus; et al.

MicroRNA expression in KRAS- and BRAF-mutated colorectal cancers

Anticancer Research, International Institute of Anticancer Research 2018, Vol. 38, (2) : 677-683

Lundberg, Ida; Wikberg, Maria L.; Ljuslinder, Ingrid; et al.

Cancer-associated fecal microbial markers in colorectal cancer detection

International Journal of Cancer, John Wiley & Sons 2017, Vol. 141, (12) : 2528-2536

Eklöf, Vincy; Löfgren-Burström, Anna; Zingmark, Carl; et al.

TAP1 down-regulation elicits immune escape and poor prognosis in colorectal cancer

Oncoimmunology, Vol. 6, (11)

Ling, Agnes; Löfgren-Burström, Anna; Larsson, Pär; et al.

Neutrophil infiltration is a favorable prognostic factor in early stages of colon cancer

Human Pathology, Vol. 68 : 193-202

Wikberg, Maria L.; Ling, Agnes; Li, Xingru; et al.

The infiltration, and prognostic importance, of Th1 lymphocytes vary in molecular subgroups of colorectal cancer

The Journal of Pathology: Clinical Research, John Wiley & Sons 2016, Vol. 2, (1) : 21-31

Ling, Agnes; Lundberg, Ida V.; Eklöf, Vincy; et al.

SOX2 expression is associated with a cancer stem cell state and down-regulation of CDX2 in colorectal cancer

BMC Cancer, Vol. 16

Lundberg, Ida V.; Edin, Sofia; Eklöf, Vincy; et al.

Secreted Factors from Colorectal and Prostate Cancer Cells Skew the Immune Response in Opposite Directions

Scientific Reports, Nature Publishing Group 2015, Vol. 5

Lundholm, Marie; Hägglöf, Christina; Wikberg, Maria L.; et al.

The intratumoural subsite and relation of CD8(+) and FOXP3(+) T lymphocytes in colorectal cancer provide important prognostic clues

British Journal of Cancer, Nature Publishing Group 2014, Vol. 110, (10) : 2551-2559

Ling, Agnes; Edin, Sofia; Wikberg, Maria L.; et al.

SOX2 expression is regulated by BRAF and contributes to poor patient prognosis in colorectal cancer

PLOS ONE, Public library of science 2014, Vol. 9, (7)

Lundberg, Ida V; Löfgren Burström, Anna; Edin, Sofia; et al.

Macrophages: Good guys in colorectal cancer

Oncoimmunology, Vol. 2, (2) : e23038-

Edin, Sofia; Wikberg, Maria L; Oldenborg, Per-Arne; et al.

Phenotypic skewing of macrophages in vitro by secreted factors from colorectal cancer cells

PLOS ONE, PLoS, Public Library of Science 2013, Vol. 8, (9) : e74982-

Edin, Sofia; Wikberg, Maria L; Rutegård, Jörgen; et al.

The prognostic role of KRAS, BRAF, PIK3CA and PTEN in colorectal cancer

British Journal of Cancer, Nature Publishing Group 2013, Vol. 108, (10) : 2153-2163

Eklöf, Vincy; Wikberg, Maria L.; Edin, Sofia; et al.

The assiciation of immune cell infiltration and prognosis in colorectal cancer

Current colorectal cancer reports, Springer 2013, Vol. 9, (4) : 372-379

Palmqvist, Richard; Wikberg, Maria L; Ling, Agnes; et al.

High intratumoral expression of fibroblast activation protein (FAP) in colon cancer is associated with poorer patient prognosis.

Tumor Biology, Springer Netherlands 2013, Vol. 34, (2) : 1013-1020

Wikberg, Maria L.; Edin, Sofia; Lundberg, Ida V.; et al.

The Distribution of Macrophages with a M1 or M2 Phenotype in Relation to Prognosis and the Molecular Characteristics of Colorectal Cancer

PLOS ONE, PLoS One 2012, Vol. 7, (10) : e47045-

Edin, Sofia; Wikberg, Maria L.; Dahlin, Anna M.; et al.

High tumour cannabinoid CB(1) receptor immunoreactivity negatively impacts disease-specific survival in stage II microsatellite stable colorectal cancer

PLOS ONE, San Francisco, CA: Public Library of Science 2011, Vol. 6, (8) : 1-11

Gustafsson, Sofia B; Palmqvist, Richard; Henriksson, Maria L; et al.

Colorectal Cancer Cells Activate Adjacent Fibroblasts Resulting in FGF1/FGFR3 Signaling and Increased Invasion.

American Journal of Pathology, Elsevier 2011, Vol. 178, (3) : 1387-1394

Henriksson, Maria L; Edin, Sofia; Dahlin, Anna M; et al.

CaMKII targets Bcl10 in T-cell receptor induced activation of NF-κB

Molecular Immunology, Oxford: 2011, Vol. 48, (12-13) : 1448-1460

Oruganti, Sreenivasa Rao; Edin, Sofia; Grundström, Christine; et al.

CaMKII targets Bc110 in T-cell receptor induced activation of NF-κB

Molecular Immunology, Elsevier 2011, Vol. 48, (12-13) : 1448-1460

Oruganti, Sreenivasa Rao; Edin, Sofia; Grundström, Christine; et al.

Interaction of calmodulin with Bcl10 modulates NF-kappaB activation.

Molecular Immunology, Elsevier 2010, Vol. 47, (11-12) : 2057-2064

Edin, Sofia; Oruganti, Sreenivasa Rao; Grundström, Christine; et al.

Regulation of c-Rel Nuclear Localization by Binding of Ca2+/Calmodulin

Molecular and Cellular Biology, American Society for Microbiology 2003, Vol. 23, (4) : 1418-1427

Antonsson, Åsa; Hughes, Kate; Edin, Sofia; et al.

Calmodulin-dependent kinase II mediates T cell receptor/CD3- and phorbol ester-induced activation of IkappaB kinase.

Journal of Biological Chemistry, Vol. 276, (38) : 36008-36013

Hughes, K; Edin, Sofia; Antonsson, A; et al.

Calmodulin-dependent Kinase II Mediates T Cell Receptor/CD3- and Phorbol Ester-induced Activation of IκB Kinase

Journal of Biological Chemistry, Vol. 276, (38) : 36008-36013

Hughes, Kate; Edin, Sofia; Antonsson, Åsa; et al.

The combined diagnostic value of faecal haemoglobin and calprotectin in colorectal cancer

Eklöf, Vincy; Lundgren, David; Karling, Pontus; et al.

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Research groups

Group member

Richard Palmqvist Lab