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Sead Crnalic
Professor of Orthopaedic Surgery
Contact
E-mail
sead.crnalic@umu.se
Phone
Works at
Affiliation
Professor, senior consultant (attending) physician at
Department of Diagnostics and Intervention
Section: Orthopedics
Location
1D, Målpunkt T21, Norrlands universitetssjukhus
Umeå universitet, 901 85 Umeå
Publications
Publications
Research
Research
2024
Denosumab combined with radiotherapy as an alternative to surgery for advanced metastatic bone lesions and pathologic fractures: a retrospective case study of 38 patients
Acta Oncologica
, Medical Journals Sweden 2024, Vol. 63, (1) : 932-938
Farhang, Mehdy; Isaksson, Martin; Wänman, Johan; et al.
2024
Uncemented trabecular metal high-flex posterior-stabilized monoblock total knee arthroplasty in patients aged 60 years or younger
Knee (Oxford)
, Elsevier 2024, Vol. 46 : 99-107
Wojtowicz, Radoslaw; Otten, Volker T C; Henricson, Anders; et al.
2023
Investigating microRNA Profiles in Prostate Cancer Bone Metastases and Functional Effects of microRNA-23c and microRNA-4328
Cancers
, MDPI 2023, Vol. 15, (9)
Järemo, Helena; Semenas, Julius; Halin Bergström, Sofia; et al.
2023
Ortopedisk forskning vid Umeå universitet
Ortopediskt magasin
, Järna: Svensk ortopedisk förening 2023, (1) : 22-25
Morberg, Per; Paradowski, Przemyslaw; Röding, Fredrik; et al.
2023
A novel radiographic pattern related to poor prognosis in patients with prostate cancer with metastatic spinal cord compression
European Urology Open Science
, Elsevier 2023, Vol. 48 : 44-53
Wänman, Johan; Abul-Kasim, Kasim; Semenas, Julius; et al.
2022
11-Year outcomes in patients with metal-on-metal ASR hip arthroplasty
Journal of Orthopaedics
, Elsevier BV 2022, Vol. 32 : 98-103
Bitar, Christian; Moberg, Ivan; Krupic, Ferid; et al.
2022
Peri-implant femoral fractures in hip fracture patients treated with osteosynthesis: a retrospective cohort study of 1965 patients
European Journal of Trauma and Emergency Surgery
, Springer 2022, Vol. 48 : 293-298
Kruse, Mark; Mohammed, Jabbar; Sayed-Noor, Arkan; et al.
2022
Evaluation of a new cemented highly cross-linked all-polyethylene cup: a prospective and randomised study assessing wear and fixation characteristics using radiostereometric analysis
HIP International
, Sage Publications 2022, Vol. 32, (6) : 779-786
Otten, Volker; Wästerlund, Daniel; Lindbjörn, John; et al.
2022
Clinical and biological relevance of the transcriptomic-based prostate cancer metastasis subtypes MetA-C
Molecular Oncology
, John Wiley & Sons 2022, (4)
Thysell, Elin; Köhn, Linda; Semenas, Julius; et al.
2022
Epithelial and stromal characteristics of primary tumors predict the bone metastatic subtype of prostate cancer and patient survival after androgen-deprivation therapy
Cancers
, MDPI 2022, Vol. 14, (21)
Wikström, Pernilla; Halin Bergström, Sofia; Josefsson, Andreas; et al.
2021
Living with a recalled implant: a qualitative study of patients' experiences with ASR hip resurfacing arthroplasty
Patient Safety in Surgery
, BMC 2021, Vol. 15, (1)
Bitar, Christian; Krupic, Ferid; Fellaender-Tsai, Li; et al.
2021
A novel DNA methylation signature is associated with androgen receptor activity and patient prognosis in bone metastatic prostate cancer
Clinical Epigenetics
, BioMed Central 2021, Vol. 13, (1)
Bovinder Ylitalo, Erik; Thysell, Elin; Landfors, Mattias; et al.
2021
Socioeconomic variables and fracture risk in children and adolescents: A population-based study from northern Sweden
BMJ Open
, BMJ Publishing Group Ltd 2021, Vol. 11, (10)
Hedström, Erik; Crnalic, Sead; Kullström, Antonia; et al.
2021
The accuracy of digital templating in cementless total hip arthroplasty in dysplastic hips
BMC Musculoskeletal Disorders
, BioMed Central 2021, Vol. 22, (1)
Kristoffersson, Emelie; Otten, Volker T C; Crnalic, Sead
2021
Predictive Value of the Spinal Instability Neoplastic Score for Survival and Ambulatory Function After Surgery for Metastatic Spinal Cord Compression in 110 Patients with Prostate Cancer
Spine
, Wolters Kluwer 2021, Vol. 46, (8) : 550-558
Wänman, Johan; Jernberg, Johannes; Gustafsson, Patrik; et al.
2019
Uncemented or cemented femoral components work equally well in total knee arthroplasty
Knee Surgery, Sports Traumatology, Arthroscopy
, Springer 2019, Vol. 27, (4) : 1251-1258
Henricson, Anders; Wojtowicz, Radek; Nilsson, Kjell G; et al.
2019
Uncemented cups with and without screw holes in primary THA: a Swedish Hip Arthroplasty Register study with 22,725 hips
Acta Orthopaedica
, Taylor & Francis Group 2019, Vol. 90, (3) : 258-263
Otten, Volker T C; Mukka, Sebastian; Nilsson, Kjell G; et al.
2019
Gene expression profiles define molecular subtypes of prostate cancer bone metastases with different outcomes and morphology traceable back to the primary tumor
Molecular Oncology
, John Wiley & Sons 2019, Vol. 13, (8) : 1763-1777
Thysell, Elin; Vidman, Linda; Bovinder Ylitalo, Erik; et al.
2019
Uncemented monoblock trabecular metal posterior stabilized high-flex total knee arthroplasty: similar pattern of migration to the cruciate-retaining design - a prospective radiostereometric analysis (RSA) and clinical evaluation of 40 patients (49 knees) 60 years or younger with 9 years' follow-up
Acta Orthopaedica
, Taylor & Francis 2019, Vol. 90, (5) : 460-466
Wojtowicz, Radoslaw; Henricson, Anders; Nilsson, Kjell G; et al.
2018
Bone remodeling in relation to androgen receptor activity in prostate cancer bone metastases
Cancer Research
, American Association for Cancer Research 2018, Vol. 78, (16) : 50-50
Bovinder Ylitalo, Erik; Nordstrand, Annika; Thysell, Elin; et al.
2018
The proteome of prostate cancer bone metastases
Cancer Research
, American Association for Cancer Research 2018, Vol. 78, (16) : 91-92
Iglesias-Gato, Diego; Thysell, Elin; Crnalic, Sead; et al.
2018
The Proteome of Prostate Cancer Bone Metastasis Reveals Heterogeneity with Prognostic Implications
Clinical Cancer Research
, American Association for Cancer Research 2018, Vol. 24, (21) : 5433-5444
Iglesias-Gato, Diego; Thysell, Elin; Tyanova, Stefka; et al.
2018
Bone Cell Activity in Clinical Prostate Cancer Bone Metastasis and Its Inverse Relation to Tumor Cell Androgen Receptor Activity
International Journal of Molecular Sciences
, MDPI 2018, Vol. 19, (4)
Nordstrand, Annika; Bovinder Ylitalo, Erik; Thysell, Elin; et al.
2018
Clinically relevant molecular subgroups of prostate cancer bone metastases
Cancer Research
, American Association for Cancer Research 2018, Vol. 78, (16) : 123-123
Thysell, Elin; Bovinder Ylitalo, Erik; Jernberg, Emma; et al.
2017
Subgroups of castration-resistant prostate cancer bone metastases defined through an inverse relationship between androgen receptor activity and immune response
European Urology
, Vol. 71, (5) : 776-787
Bovinder Ylitalo, Erik; Thysell, Elin; Jernberg, Emma; et al.
2017
High Levels of the AR-V7 Splice Variant and Co-Amplification of the Golgi Protein Coding YIPF6 in AR Amplified Prostate Cancer Bone Metastases
The Prostate
, Wiley-Blackwell Publishing Inc. 2017, Vol. 77, (6) : 625-638
Djusberg, Erik; Jernberg, Emma; Thysell, Elin; et al.
2017
Muscle oxygenation in Type 1 diabetic and non-diabetic patients with and without chronic compartment syndrome
PLoS Medicine
, Public library science 2017, Vol. 12, (10)
Gustafsson, Patrik; Crenshaw, Albert G.; Edmundsson, David; et al.
2017
Metastatic spinal cord compression as the first sign of malignancy: Outcome after surgery in 69 patients
Acta Orthopaedica
, Taylor & Francis 2017, Vol. 88, (4) : 457-462
Wänman, Johan; Grabowski, Pawel; Nyström, Helena; et al.
2016
Association between changes in global femoral offset after total hip arthroplasty and function, quality of life, and abductor muscle strength: A prospective cohort study of 222 patients
Acta Orthopaedica
, Taylor & Francis 2016, Vol. 87, (1) : 36-41
Mahmood, Sarwar S.; Mukka, Sebastian S.; Crnalic, Sead; et al.
2016
Stability of Uncemented Cups - Long-Term Effect of Screws, Pegs and HA Coating: A 14-Year RSA Follow-Up of Total Hip Arthroplasty
The Journal of Arthroplasty
, Vol. 31, (1) : 156-161
Otten, Volker T C; Crnalic, Sead; Röhrl, Stephan M; et al.
2015
The Influence of Leg Length Discrepancy after Total Hip Arthroplasty on Function and Quality of Life: a Prospective Cohort Study
The Journal of Arthroplasty
, Elsevier 2015, Vol. 30, (9) : 1638-1642
Mahmood, Sarwar; Mukka, Sebastian S; Crnalic, Sead; et al.
2014
Metastatisk ryggmärgskompression får inte missas: ökad medvetenhet om tidiga symtom möjliggör snabb behandling
Läkartidningen
, Stockholm: Sveriges läkarförbund 2014, Vol. 111, (7) : 276-277
Crnalic, Sead
2013
Early diagnosis and treatment is crucial for neurological recovery after surgery for metastatic spinal cord compression in prostate cancer
Acta Oncologica
, London: Informa Healthcare 2013, Vol. 52, (4) : 809-815
Crnalic, Sead; Hildingsson, Christer; Bergh, Anders; et al.
2013
Characterization of prostate cancer bone metastases according to expression levels of steroidogenic enzymes and androgen receptor splice variants
PLOS ONE
, Public Library of Science 2013, Vol. 8, (11) : e77407-
Jernberg, Emma; Thysell, Elin; Bovinder Ylitalo, Erik; et al.
2012
Metastatic spinal cord compression in prostate cancer: clinical and morphological studies
Umeå University medical dissertations
, 1487
Crnalic, Sead
2012
Outcome after surgery for metastatic spinal cord compression in 54 patients with prostate cancer
Acta Orthopaedica
, Informa Healtcare 2012, Vol. 83, (1) : 80-86
Crnalic, Sead; Hildingsson, Christer; Wikström, Pernilla; et al.
2012
Predicting survival for surgery of metastatic spinal cord compression in prostate cancer: a new score
Spine
, Vol. 37, (26) : 2168-2176
Crnalic, Sead; Löfvenberg, Richard; Bergh, Anders; et al.
2011
Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival
PLOS ONE
, Vol. 6, (4) : e19059-
Hörnberg, Emma; Bovinder Ylitalo, Erik; Crnalic, Sead; et al.
2010
Nuclear androgen receptor staining in bone metastases is related to a poor outcome in prostate cancer patients
Endocrine-Related Cancer
, Vol. 17, (4) : 885-895
Crnalic, Sead; Hörnberg, Emma; Wikström, Pernilla; et al.
2010
Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol
PLoS One
, Public Library of Science 2010, Vol. 5, (12)
Thysell, Elin; Surowiec, Izabella; Hörnberg, Emma; et al.
Integrated DNA methylation and gene expression analysis of molecular heterogeneity in prostate cancer bone metastasis
Bovinder Ylitalo, Erik; Thysell, Elin; Landfors, Mattias; et al.
Socioeconomic impact on the incidence of fractures in children and adolescents: a population-based study fron northern Sweden
Hedström, Erik; Crnalic, Sead; Kullström, Antonia; et al.
Molecular features of prostate cancer bone metastases harboring androgen receptor gene amplification
Jernberg, Emma; Brattsand, Maria; Thysell, Elin; et al.
The microRNA landscape of prostate cancer bone metastases and the role of miRNA-375 in modulating phenotypic characteristics of metastatic cells
Järemo, Helena; Semenas, Julius; Halin Bergström, Sofia; et al.
Bone remodeling in relation to androgen receptor activity in prostate cancer bone metastases
Nordstrand, Annika; Bovinder-Ylitalo, Erik; Thysell, Elin; et al.
Uncemented cups with and without screw holes in primary THA: a Swedish Hip Arthroplasty Register study with 22725 hips
Otten, Volker T C; Mukka, Sebastian; Nilsson, Kjell G; et al.
Osteolysis around uncemented cups withand without screw holes: Analysis of osteolytic lesions on CT images in 48 hips at a 14-year follow-up
Otten, Volker T C; Stamenkov, Roumen; Callary, Stuart A.; et al.
View publications in DiVA
Research groups
Group member
Micael Widerström
Research projects
1 January 2023
Sensorimotor control after anterior cruciate ligament injury: towards a precision medicine approach
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