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Per Zetterström

Contact

per.zetterstrom@umu.se

+46 90 785 29 50

Works at

Assistant professor, resident physician at Department of Medical Biosciences Section: Clinical Chemistry

By 6M, vån 2, Sjukhusområdet Umeå universitet, 901 85 Umeå

Specific analysis of SOD1 enzymatic activity in CSF from ALS patients with and without SOD1 mutations

Neurobiology of Disease, Elsevier 2024, Vol. 202

Leykam, Laura; Forsberg, Karin; Nordström, Ulrika; et al.

Mutant SOD1 aggregates formed in vitro and in cultured cells are polymorphic and differ from those arising in the CNS

Journal of Neurochemistry, John Wiley & Sons 2023, Vol. 164, (1) : 77-93

Nordström, Ulrika; Lang, Lisa; Ekhtiari Bidhendi, Elaheh; et al.

The motor system is exceptionally vulnerable to absence of the ubiquitously expressed superoxide dismutase-1

Brain Communications, Oxford University Press 2023, Vol. 5, (1)

Park, Julien H.; Nordström, Ulrika; Tsiakas, Konstantinos; et al.

ALS kan vara en prionsjukdom: Inklusioner av felvecklat SOD1-protein tycks finnas hos patienter med alla typer av ALS

Läkartidningen, Läkartidningen Förlag AB 2020, Vol. 117

Forsberg, Karin; Tjust, Anton E.; Zetterström, Per; et al.

Aggregate-selective antibody attenuates seeded aggregation but not spontaneously evolving disease in SOD1 ALS model mice

Acta neuropathologica communications, BMC 2020, Vol. 8, (1)

Lehmann, Manuela; Marklund, Matthew; Bolender, Anna-Lena; et al.

Phenotype in an Infant with SOD1 Homozygous Truncating Mutation

New England Journal of Medicine, Massachusetts Medical Society 2019, Vol. 381, (5) : 486-488

Andersen, Peter M.; Hempel, Maja; Santer, René; et al.

The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension

Acta Neuropathologica, New York: Springer 2019, Vol. 138, (1) : 85-101

Keskin, Isil; Forsgren, Elin; Lehmann, Manuela; et al.

Mutant superoxide dismutase aggregates from human spinal cord transmit amyotrophic lateral sclerosis

Acta Neuropathologica, Springer 2018, Vol. 136, (6) : 939-953

Ekhtiari Bidhendi, Elaheh; Bergh, Johan; Zetterström, Per; et al.

Two superoxide dismutase prion strains transmit amyotrophic lateral sclerosis-like disease

Journal of Clinical Investigation, Vol. 126, (6) : 2249-2253

Ekhtiari Bidhendi, Elaheh; Bergh, Johan; Zetterström, Per; et al.

Structural and kinetic analysis of protein-aggregate strains in vivo using binary epitope mapping

Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 2015, Vol. 112, (14) : 4489-4494

Bergh, Johan; Zetterström, Per; Andersen, Peter M.; et al.

SOD1 aggregation in ALS mice shows simplistic test tube behavior

Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, (32) : 9878-9883

Lang, Lisa; Zetterström, Per; Brännström, Thomas; et al.

Expression of wild-type human superoxide dismutase-1 in mice causes amyotrophic lateral sclerosis

Human Molecular Genetics, Vol. 22, (1) : 51-60

Graffmo, Karin S.; Forsberg, Karin; Bergh, Johan; et al.

Composition of soluble misfolded superoxide Dismutase-1 in murine models of Amyotrophic Lateral Sclerosis

Neuromolecular medicine, Vol. 15, (1) : 147-158

Zetterström, Per; Graffmo, Karin S.; Andersen, Peter M; et al.

Cytotoxicity of Superoxide Dismutase 1 in Cultured Cells Is Linked to Zn2+ Chelation

PLOS ONE, Vol. 7, (4) : e36104-

Johansson, Ann-Sofi; Vestling, Monika; Zetterström, Per; et al.

Misfolded superoxide dismutase-1 in amyotrophic lateral sclerosis

Umeå University medical dissertations, 1421

Zetterström, Per

Misfolded superoxide dismutase-1 in CSF from amyotrophic lateral sclerosis patients

Journal of Neurochemistry, Vol. 117, (1) : 91-99

Zetterström, Per; Andersen, Peter M; Brännström, Thomas; et al.

Proteins that bind to misfolded mutant superoxide dismutase-1 in spinal cords from transgenic ALS model mice

Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2011, Vol. 286, (23) : 20130-20136

Zetterström, Per; Graffmo, Karin S; Andersen, Peter M; et al.

Functional features cause misfolding of the ALS-provoking enzyme SOD1

Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 2009, Vol. 106, (24) : 9667-9672

Nordlund, Anna; Leinartaitė, Lina; Saraboji, Kadhirvel; et al.

Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models

Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, (35) : 14157-14162

Zetterström, Per; Stewart, Heather G; Bergemalm, Daniel; et al.

Superoxide dismutase prions transmit fatal ALS to transgenic mice which do not spontaneously develop symptoms

Ekhtiari Bidhendi, Elaheh; Zetterström, Per; Andersen, Peter M.; et al.

High expression of wild-type human superoxide dismutase-1 gives a model of sporadic ALS

Forsberg, Karin; Graffmo, Karin S; Zetterström, Per; et al.

Enhanced protein misfolding in patient-derived models of amyotrophic lateral sclerosis

Forsgren, Elin; Lehmann, Manuela; Weygandt Mathis, Mackenzie; et al.

Low oxygen tension induces misfolding and aggregation of superoxide dismutase in ALS patient-derived motor neurons

Keskin, Isil; Forsgren, Elin; Andersen, Peter M.; et al.

Structure of soluble misfolded superoxide dismutase-1 in murine ALS models

Zetterström, Per; Graffmo, Karin S; Andersen, Peter M; et al.

View publications in DiVA

Research groups

Head of research

ALS Research Umeå

Head of research

Per Zetterström Lab