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Olga Nagaeva
Contact
E-mail
olga.nagaeva@umu.se
Phone
+46 90 785 22 39
Works at
Affiliation
Project assistant at
Department of Clinical Microbiology
Section: Clinical Immunology
Location
By 6B, Klinisk immunologi, Klin imm, plan 1
Umeå universitet, 901 85 Umeå
Publications
Publications
Research
Research
2024
Endometriotic tissue-derived exosomes downregulate NKG2D-mediated cytotoxicity and promote apoptosis: mechanisms for survival of endometriotic tissue at ectopic sites
Björk, Emma; Israelsson, Pernilla; Nagaev, Ivan; et al.
2024
Endometriotic tissue-derived exosomes downregulate NKg2D-mediated cytotoxicity and promote apoptosis: mechanisms for survival of ectopic endometrial tissue in endometriosis
Journal of Immunology
, The American Association of Immunologists 2024, Vol. 213, (5) : 567-576
Björk, Emma; Israelsson, Pernilla; Nagaev, Ivan; et al.
2023
NKG2D-mediated cytotoxicity improves after primary surgery for high-grade serous ovarian cancer
American Journal of Reproductive Immunology
, John Wiley & Sons 2023, Vol. 89, (1)
Israelsson, Pernilla; Björk, Emma; Nagaev, Ivan; et al.
2020
Enhanced local and systemic inflammatory cytokine mRNA expression in women with endometriosis evokes compensatory adaptive regulatory mRNA response that mediates immune suppression and impairs cytotoxicity
American Journal of Reproductive Immunology
, John Wiley & Sons 2020, Vol. 84, (4)
Björk, Emma; Vinnars, Marie-Therese; Nagaev, Ivan; et al.
2019
Assessment of cytokine mRNA expression profiles in tumor microenvironment and peripheral blood mononuclear cells of patients with high-grade serous carcinoma of the ovary
International Journal of Gynecological Cancer
, BMJ Publishing Group Ltd 2019, Vol. 29 : A138-A138
Israelsson, Pernilla; Labani-Motlagh, Alireza; Nagaev, Ivan; et al.
2017
Melanocortin 2, 3 and 4 Receptor Gene Expressions are Downregulated in CD8(+) T Cytotoxic Lymphocytes and CD19(+) B Lymphocytes in Rheumatoid Arthritis Responding to TNF- Inhibition
Scandinavian Journal of Immunology
, John Wiley & Sons 2017, Vol. 86, (1) : 31-39
Andersen, M.; Nagaev, Ivan; Meyer, M. K.; et al.
2017
Lymphocyte profile and cytokine mRNA expression in peripheral blood mononuclear cells of patients with recurrent respiratory papillomatosis suggest dysregulated cytokine mRNA response and impaired cytotoxic capacity
Immunity, Inflammation and Disease
, Wiley-Blackwell 2017, Vol. 5, (4) : 541-550
Holm, Anna; Nagaeva, Olga; Nagaev, Ivan; et al.
2017
Assessment of cytokine mRNA expression profiles in tumor microenvironment and peripheral blood mononuclear cells of patients with high-grade serous carcinoma of the ovary
Journal of Cancer Science & Therapy
, Vol. 9, (5) : 422-429
Israelsson, Pernilla; Labani-Motlagh, Alireza; Nagaev, Ivan; et al.
2016
Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity
Tumor Biology
, Vol. 37, (4) : 5455-5466
Labani-Motlagh, Alireza; Israelsson, Pernilla; Ottander, Ulrika; et al.
2016
Isolation and characterization of exosomes from cultures of tissue explants and cell lines
Current Protocols in Immunology
, Wiley-Blackwell 2016, Vol. 2016 : 14.42.1-14.42.21
Mincheva-Nilsson, Lucia; Baranov, Vladimir; Nagaeva, Olga; et al.
2016
Dynamics of cytokine mRNA expression and fecal biomarkers in school-children undergoing a double-blind placebo-controlled food challenge series
Cytokine
, Vol. 88 : 259-266
Winberg, Anna; Nagaeva, Olga; Nagaev, Ivan; et al.
2014
Adalimumab (Humira (R)) normalizes melanocortin receptor subtype 2, 3, and 4 expression in CD8+, CD14+, and CD19+leucocyte subsets in rheumatoid arthritis
Scandinavian Journal of Rheumatology
, Informa Healthcare 2014, Vol. 43, (Suppl. 127) : 25-26 Meeting Abstr. PP119
Andersen, M.; Olesen, M. K.; Nagaev, Ivan; et al.
2014
Prostate Tumor-Derived Exosomes Down-Regulate NKG2D Expression on Natural Killer Cells and CD8(+) T Cells: Mechanism of Immune Evasion
PLOS ONE
, Vol. 9, (9) : e108925-
Lundholm, Marie; Schröder, Mona; Nagaeva, Olga; et al.
2013
Exosomes secreted by human placenta carry functional Fas ligand and TRAIL molecules and convey apoptosis in activated immune cells, suggesting exosome-mediated immune privilege of the fetus
Journal of Immunology
, The American Association of Immunologists 2013, Vol. 191, (11) : 5515-5523
Stenqvist, Ann-Christin; Nagaeva, Olga; Baranov, Vladimir; et al.
2013
Galectin-1 influences trophoblast immune evasion and emerges as a predictive factor for the outcome of pregnancy
Molecular human reproduction
, Vol. 19, (1) : 43-53
Tirado-Gonzalez, Irene; Freitag, Nancy; Barrientos, Gabriela; et al.
2012
Dermal Melanocortin Receptor Rebound in Diffuse Systemic Sclerosis after Anti-TGF ss 1 Antibody Therapy
Scandinavian Journal of Immunology
, Hoboken: Wiley-Blackwell 2012, Vol. 76, (5) : 478-482
Andersen, G. Neumann; Andersen, M.; Nagaeva, Olga; et al.
2011
The Melanocortin System: A New and Important Actor on the Scene of Systemic Sclerosis
Arthritis and Rheumatism
, Malden: Wiley-Blackwell 2011, Vol. 63, (10) : S908-S908
Andersen, Grethe N.; Nagaeva, Olga; Mincheva-Nilsson, Lucia; et al.
2011
Maternal Foxp3 expressing CD4+ CD25+ and CD4+ CD25- regulatory T-cell populations are enriched in human early normal pregnancy decidua: a phenotypic study of paired decidual and peripheral blood samples.
American Journal of Reproductive Immunology and Microbiology
, John Wiley & Sons 2011, Vol. 66, (Suppl 1) : 44-56
Dimova, Tanya; Nagaeva, Olga; Stenqvist, Ann-Christin; et al.
2011
Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells
PLOS ONE
, Vol. 6, (2) : e16899-
Hedlund, Malin; Nagaeva, Olga; Kargl, Dominic; et al.
2011
Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells
PLOS ONE
, Public Library of Science 2011, Vol. 6, (2)
Hedlund, Malin; Nagaeva, Olga; Kargl, Dominic; et al.
2009
Human placenta expresses and secretes NKG2D ligands via exosomes that down-modulate the cognate receptor expression: evidence for immunosuppressive function
Journal of Immunology
, Vol. 183, (1) : 340-351
Hedlund, Malin; Stenqvist, Ann-Christin; Nagaeva, Olga; et al.
2008
An efficient optimized method for isolation of villous trophoblast cells from human early pregnancy placenta suitable for functional and molecular studies
American Journal of Reproductive Immunology and Microbiology
, Vol. 60, (1) : 33-42
Stenqvist, Ann-Christin; Chen, Ting; Hedlund, Malin; et al.
2005
Quantitative measurement of the levels of melanocortin receptor subtype 1, 2, 3 and 5 and pro-opio-melanocortin peptide gene expression in subsets of human peripheral blood leucocytes
Scandinavian Journal of Immunology
, Oxford: Blackwell Publishing 2005, Vol. 61, (3) : 279-284
Andersen, Grethe; Hägglund, M; Nagaeva, Olga; et al.
2000
Lipids are a constitutive component of cytolytic granules.
Histochemistry and Cell Biology
, Vol. 114, (2) : 167-71
Baranov, Vladimir; Nagaeva, Olga; Hammarström, Sten; et al.
Enhanced CD56 expression and increased numbers of CD56
+bright
cells in the peripheral blood of untreated endometriosis patients
Björk, Emma; Israelsson, Pernilla; Nagaeva, Olga; et al.
The influence of surgery on circulating ovarian cancer exosomes and the NKG2D‐mediated cytotoxicity
Israelsson, Pernilla; Björk, Emma; Nagaev, Ivan; et al.
View publications in DiVA
Research groups
Group member
Lucia Mincheva-Nilsson
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