Lingyu Li is working as a postdoctoral fellow in the group Sun Nyunt Wai and group Saskia Erttmann.
In her current project, Lingyu is investigating the effects of a novel bacterial cytotoxin on tumor progression and immune cell signaling. Motility-associated killing factor A (MakA), a novel cytotoxin secreted from Vibrio cholera, is therapeutically active against colon cancer cell (CRC) growth. Her research purpose is to investigate how MakA alters the tumor microenvironment, including the equilibrium of cytokines and other inflammatory mediators, which may play a role in MakA-dependent cancer regression.
Bio
Lingyu studied biology at Shanghai Ocean University where she discovered her interest in nutrition physiology research. Then she joined the Laboratory of Aquaculture Nutrition and Environmental Health (LANEH) in East China Normal University (ECNU), and received her PhD degree major in Metabolic Physiology in 2020.
Her PhD research focused on investigating the molecular regulation of energy homeostasis reprogramming, especially in the fish models (tilapia and zebrafish). After her PhD she worked as a research assistant in Professor Du’s lab in LANEH. Then, she joined the group of Saskia Erttmann in February 2021. Thus she changed the research field to immunity to identify new molecular players in innate immunity regulation. Now, she’s working in group Sun Nyunt Wai and group Saskia Erttmann.