Jonas Nilsson

Our group have an approach driving projects to personalize cancer medicine and decipher tumor information into actionable knowledge.

Research qualifications: Docent

Contact

jonas.a.nilsson@umu.se

+46 90 785 85 61

Works at

Research fellow at Department of Diagnostics and Intervention Section: Oncology

Målpunkt M31, Byggnad 6M, plan 3, Norrlands universitetssjukhus, Translationellt forskningscentrum (TRC) Umeå universitet, 901 85 Umeå

One research focus relates to the interaction between cancer cells and their microenvironment, and how the tumor can circumvent the immunosurveillance, called immune editing, and the new line of immunotherapies directed against them, e.g. check-point inhibitors.

KRAS G12C-mutant driven non-small cell lung cancer (NSCLC)

Critical reviews in oncology/hematology, Elsevier 2024, Vol. 195

Rosell, Rafael; Codony-Servat, Jordi; González, Jessica; et al.

Use of CAM among cancer patients: results of a regional survey in Sweden

BMC Complementary Medicine and Therapies, BioMed Central (BMC) 2023, Vol. 23, (1)

Källman, Mikael; Bergström, Stefan; Carlsson, Tobias; et al.

Detection and localization of early- and late-stage cancers using platelet RNA

Cancer Cell, Elsevier 2022, Vol. 40, (9) : 999-1009.e6

In ’t Veld, Sjors G.J.G.; Arkani, Mohammad; Post, Edward; et al.

Clinical and biological relevance of the transcriptomic-based prostate cancer metastasis subtypes MetA-C

Molecular Oncology, John Wiley & Sons 2022, (4)

Thysell, Elin; Köhn, Linda; Semenas, Julius; et al.

Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma

Cell Reports Medicine, Elsevier 2020, Vol. 1, (7)

Sol, Nik; 't Veld, Sjors G. J. G. in; Vancura, Adrienne; et al.

Platelets harbor prostate cancer biomarkers and the ability to predict therapeutic response to abiraterone in castration resistant patients

The Prostate, Wiley-Blackwell 2018, Vol. 78, (1) : 48-53

Tjon-Kon-Fat, Lee-Ann; Lundholm, Marie; Schröder, Mona; et al.

Platelet RNA in Cancer Diagnostics

Seminars in Thrombosis and Hemostasis, THIEME MEDICAL PUBL INC 2018, Vol. 44, (2) : 135-141

Tjon-Kon-Fat, Lee-Ann; Sol, Nik; Wurdinger, Thomas; et al.

Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets

Cancer Cell, Elsevier 2017, Vol. 32, (2) : 238-252

Best, Myron G.; Sol, Nik; 't Veld, Sjors G. J. G. In; et al.

The prognostic value of pre-treatment leukocytosis in patients with previously treated, stage IIIB/IV non-small cell lung cancer treated with the IGF-1R pathway modulator AXL1717 or docetaxel: a retrospective analysis of a phase II trial

Asian Pacific Journal of Cancer Prevention, Vol. 18, (6) : 1555-1560

Holgersson, Georg; Bergqvist, Michael; Nilsson, R. Jonas A.; et al.

The prognostic value of pre-treatment thrombocytosis in two cohorts of patients with non-small cell lung cancer treated with curatively intended chemoradiotherapy

Neoplasma (Bratislava), Bratislava: AEPress 2017, Vol. 64, (6) : 909-915

Holgersson, Georg; Bergström, Stefan; Hallqvist, Anders; et al.

Liquid biopsies in lung cancer: time to implement research technologies in routine care?

Annals of Translational Medicine, AME Publishing Company 2017, Vol. 5, (13)

Köhn, Linda; Johansson, Mikael; Grankvist, Kjell; et al.

miR-129-3p controls centrosome number in metastatic prostate cancer cells by repressing CP110

Oncotarget, Vol. 7, (13) : 16676-16687

Bijnsdorp, Irene V.; Hodzic, Jasmina; Lagerweij, Tonny; et al.

Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer

Oncotarget, Vol. 7, (1) : 1066-1075

Nilsson, R. Jonas A.; Karachaliou, Niki; Berenguer, Jordi; et al.

RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

Cancer Cell, Vol. 28, (5) : 666-676

Best, Myron G.; Sol, Nik; Kooi, Irsan; et al.

Tumor-educated platelets allow for multiclass liquid biopsy-based diagnosis of cancer

Cancer Research, American Association for Cancer Research 2015, Vol. 75, (Suppl. 15)

Best, Myron; Sol, Nik; Kooi, Irsan; et al.

Allowance of tumor-educated platelets for multiclass liquid biopsy-based diagnosis of cancer

Journal of Clinical Oncology, American Society of Clinical Oncology 2015, Vol. 33, (15, suppl.)

Best, Myron; Sol, Nik; Kooi, Irsan; et al.

Multiplex functional bioluminescent reporters using gaussia luciferase fused to epitope tags in an immunobinding assay

Bioluminescent imaging: methods and protocols, Humana Press 2014 : 231-247

Van Rijn, Sjoerd; Würdinger, Thomas; Nilsson, R. Jonas A.

Effects of the Selective MPS1 Inhibitor MPS1-IN-3 on Glioblastoma Sensitivity to Antimitotic Drugs

Journal of the National Cancer Institute, Oxford University Press 2013, Vol. 105, (17) : 1322-1331

Tannous, Bakhos A.; Kerami, Mariam; Van der Stoop, Petra M.; et al.

Functional multiplex reporter assay using tagged Gaussia luciferase

Scientific Reports, Nature Publishing Group 2013, Vol. 3

Van Rijn, S.; Nilsson, Jonas; Noske, D. P.; et al.

Transcription Factor Activity Analysis Using a Functional Multiplex Gaussia Luciferase-Based Reporter Assay

Molecular Therapy, Nature Publishing Group 2013, Vol. 21 : S123-S124

van Rijn, Sjoerd; Nilsson, Jonas; Noske, David P.; et al.

Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor-related apoptosis-inducing ligand and induces an alternative cell death pathway.

Neuro-Oncology, Vol. 13, (11) : 1213-1224

Badr, Christian E; Wurdinger, Thomas; Nilsson, Jonas; et al.

Blood platelets contain tumor-derived RNA biomarkers

Blood, New York: 2011, Vol. 118, (13) : 3680-3683

Nilsson, R. Jonas A.; Balaj, Leonora; Hulleman, Esther; et al.

Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2

PLOS ONE, Vol. 6, (1) : e16282-

Smits, Michiel; Mir, Shahryar E; Nilsson, Jonas; et al.

Paracrine regulation of growth factor signaling by shed leucine-rich repeats and immunoglobulin-like domains 1

Experimental Cell Research, New York: Academic Press 2011, Vol. 317, (4) : 504-512

Yi, Wei; Holmlund, Camilla; Nilsson, Jonas; et al.

miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis

Oncotarget, Impact Journals LLC 2010, Vol. 1, (8) : 710-720

Smits, Michiel; Nilsson, Jonas; Mir, Shahryar E; et al.

Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer.

British journal of cancer, Vol. 100, (10) : 1603-1607

Nilsson, Jonas; Skog, Johan; Nordstrand, Annika; et al.

Establishment and validation of an in vitro co-culture model to study the interactions between bone and prostate cancer cells

Clinical & experimental metastasis, Vol. 26, (8) : 945-953

Nordstrand, Annika; Nilsson, Jonas; Tieva, Åse; et al.

Perinuclear leucine-rich repeats and immunoglobulin-like domain proteins (LRIG1-3) as prognostic indicators in astrocytic tumors

Acta Neuropathologica, Vol. 111, (3) : 238-346

Guo, Dongsheng; Nilsson, Jonas; Haapasalo, Hannu; et al.

The LRIG-family: identification of novel regulators of ErbB signaling with clinical implications in astrocytoma

Umeå University medical dissertations, 1027

Nilsson, Jonas

LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation

EMBO Journal, Vol. 23, (16) : 3270-3281

Gur, Gal; Rubin, Chanan; Katz, Menachem; et al.

Characterization and tissue-specific expression of human LRIG2

Gene, Vol. 332 : 35-43

Holmlund, Camilla; Nilsson, Jonas; Guo, Dongsheng; et al.

LRIG1 protein in human cells and tissues

Cell and Tissue Research, Vol. 312, (1) : 65-71

Nilsson, Jonas; Starefeldt, Anna; Henriksson, Roger; et al.

Adenovirus type 37 binds to cell surface sialic acid through a charge-dependent interaction

Virology, Elsevier 2002, Vol. 302, (1) : 33-43

Arnberg, Niklas; Kidd, Alistair H; Edlund, Karin; et al.

Is LRIG1 a tumour suppressor gene at chromosome 3p14.3?

Acta Oncologica, Vol. 41, (4) : 352-354

Hedman, Håkan; Nilsson, Jonas; Guo, Dongsheng; et al.

Cloning, characterization and expression of human LIG1

Biochemical and Biophysical Research Communications - BBRC, Vol. 284, (5) : 1155-1161

Nilsson, Jonas; Vallbo, Christina; Guo, Dongsheng; et al.

View publications in DiVA

Research groups

Head of research

Jonas Nilsson lab