Jeanette Bröms

Associate Professor of Biomedical Laboratory Science

Docent in Medical Microbiology

Research qualifications: Docent

0009-0004-2793-8098

Contact

jeanette.broms@umu.se

+46 90 785 11 14

Works at

Associate professor at Department of Clinical Microbiology Section: Biomedical Laboratory Science, Clinical Bacteriology

6D, Bakt Lab, Universitetssjukhuset, 2B Umeå universitet, 901 85 Umeå

The type IV pili component PilO is a virulence determinant of Francisella novicida

PLOS ONE, Public Library of Science 2022, Vol. 17, (1 1)

Ozanic, Mateja; Marecic, Valentina; Knezevic, Masa; et al.

The Role of ClpB in Bacterial Stress Responses and Virulence

Frontiers in Molecular Biosciences, Frontiers Media S.A. 2021, Vol. 8

Alam, Athar; Bröms, Jeanette E; Kumar, Rajender; et al.

Exploring the Diversity Within the Genus Francisella – An Integrated Pan-Genome and Genome-Mining Approach

Frontiers in Microbiology, Frontiers Media S.A. 2020, Vol. 11

Kumar, Rajender; Bröms, Jeanette E; Sjöstedt, Anders

A mutagenesis-based approach identifies amino acids in the N-terminal part of Francisella tularensis IglE that critically control type VI system-mediated secretion

Virulence, TAYLOR & FRANCIS INC 2017, Vol. 8, (6) : 821-847

Bröms, Jeanette E.; Meyer, Lena; Sjöstedt, Anders

The amino-terminal part of the needle-tip translocator LcrV of Yersinia pseudotuberculosis is required for early targeting of YopH and in vivo virulence

Frontiers in Cellular and Infection Microbiology, Vol. 6

Ekestubbe, Sofie; Bröms, Jeanette E.; Edgren, Tomas; et al.

Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for Virulence

PLoS Pathogens, Vol. 12, (9)

Rigard, Melanie; Bröms, Jeanette E.; Mosnier, Amandine; et al.

Microinjection of Francisella tularensis and Listeria monocytogenes reveals the importance of bacterial and host factors for successful replication

Infection and Immunity, Vol. 83, (8) : 3233-3242

Meyer, Lena; Bröms, Jeanette; Liu, Xijia; et al.

Screening for inhibition of Vibrio cholerae VipA-VipB interaction identifies small-molecule compounds active against type VI secretion

Antimicrobial Agents and Chemotherapy, Vol. 58, (7) : 4123-4130

Sun, Kun; Bröms, Jeanette; Lavander, Moa; et al.

A functional VipA-VipB interaction is required for the type VI secretion system activity of Vibrio cholerae O1 strain A1552

BMC Microbiology, London, England: BioMed Central 2013, Vol. 13 : 96-

Bröms, Jeanette E.; Ishikawa, Takahiko; Wai, Sun N.; et al.

A study of virulence factors in the fish pathogen F. noatunensis ssp noatunensis

Fish and Shellfish Immunology, Elsevier 2013, Vol. 34, (6) : 1716-1716

Lampe, E. O.; Zingmark, Carl; Hemnann, L.; et al.

The Francisella tularensis LVS ΔpdpC mutant exhibits a unique phenotype during intracellular infection

BMC Microbiology, BioMed Central 2013, Vol. 13

Lindgren, Marie; Bröms, Jeanette E.; Meyer, Lena; et al.

Importance of PdpC, IglC, IglI, and IglG for Modulation of a Host Cell Death Pathway Induced by Francisella tularensis

Infection and Immunity, Vol. 81, (6) : 2076-2084

Lindgren, Marie; Eneslätt, Kjell; Bröms, Jeanette; et al.

DotU and VgrG, core components of type VI secretion systems, are essential for Francisella LVS pathogenicity

PLOS ONE, Vol. 7, (4)

Bröms, Jeanette E.; Meyer, Lena; Lavander, Moa; et al.

Unique substrates secreted by the type VI secretion system of Francisella tularensis during intramacrophage infection

PLOS ONE, Vol. 7, (11)

Bröms, Jeanette E.; Meyer, Lena; Sun, Kun; et al.

Pathoadaptive conditional regulation of the type VI secretion system in Vibrio cholerae O1 strains

Infection and Immunity, American Society for Microbiology 2012, Vol. 80, (2) : 575-584

Ishikawa, Takahiko; Sabharwal, Dharmesh; Bröms, Jeanette; et al.

Impact of the N-terminal secretor domain on YopD translocator function in Yersinia pseudotuberculosis type III secretion

Journal of Bacteriology, American Society for Microbiology 2011, Vol. 193, (23) : 6683-6700

Amer, Ayad; Åhlund, Monika; Bröms, Jeanette; et al.

IglG and IglI of the Francisella pathogenicity island are important virulence determinants of Francisella tularensis LVS

Infection and Immunity, American Society for Microbiology 2011, Vol. 79, (9) : 3683-3696

Bröms, Jeanette E; Lavander, Moa; Meyer, Lena; et al.

Dissection of the Functions of the IglC Protein of Francisella tularensis

The challenge of highly pathogenic microorganisms: mechanisms of virulence and novel medical countermeasures, Springer 2010 : 67-75

Bröms, Jeanette E; Lavander, Moa; Sjöstedt, Anders

The role of the Francisella Tularensis pathogenicity island in type VI secretion, intracellular survival, and modulation of host cell signaling

Frontiers in microbiology, Vol. 1 : 136-

Bröms, Jeanette E; Sjöstedt, Anders; Lavander, Moa

YopD self-assembly and binding to LcrV facilitate type III secretion activity by Yersinia pseudotuberculosis

Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2010, Vol. 285, (33) : 25269-25284

Costa, Tiago R D; Edqvist, Petra J; Bröms, Jeanette E; et al.

A conserved α-helix essential for a type VI secretion-like system of Francisella tularensis

Journal of Bacteriology, Vol. 191, (8) : 2431-2446

Bröms, Jeanette E; Lavander, Moa; Sjöstedt, Anders

The Twin Arginine Translocation System is Essential for Virulence of Yersinia pseudotuberculosis

Infection and Immunity, American Society for Microbiology 2006, Vol. 74, (3) : 1768-1776

Lavander, Moa; Ericsson, Solveig K.; Bröms, Jeanette E; et al.

Mapping of a YscY binding domain within the LcrH chaperone that is required for regulation of Yersinia type III secretion

Journal of Bacteriology, American Society for Microbiology 2005, Vol. 187, (22) : 7738-7752

Bröms, Jeanette E; Edqvist, Petra J; Carlsson, Katrin E; et al.

Type III secretion- the various functions of the translocon operon in bacterial pathogenesis

Umeå: Molekylärbiologi 2004

Bröms, Jeanette E

Polarisation of type III translocation by Pseudomonas aeruginosa requires PcrG, PcrV and PopN

Microbial Pathogenesis, Academic Press 2004, Vol. 37, (6) : 313-322

Sundin, Charlotta; Thelaus, Johanna; Bröms, Jeanette E; et al.

PcrH of Pseudomonas aeruginosa is essential for secretion and assembly of the type III translocon

Journal of Infectious Diseases, Vol. 188, (12) : 1909-1921

Bröms, Jeanette; Forslund, Anna-Lena; Forsberg, Åke; et al.

Dissection of homologous translocon operons reveals a distinct role for YopD in type III secretion by Yersinia pseudotuberculosis

Microbiology, Microbiology Society Journals 2003, Vol. 149, (9) : 2615-2626

Bröms, Jeanette; Forslund, Anna-Lena; Forsberg, Åke; et al.

Comparative analysis of type III effector translocation by Yersinia pseudotuberculosis expressing native LcrV or PcrV from Pseudomonas aeruginosa

Journal of Infectious Diseases, Vol. 188, (2) : 239-249

Bröms, Jeanette; Sundin, Charlotta; Francis, Matthew; et al.

Mapping of an YscY binding regulatory domain within the type III secretion chaperone LcrH of Yersinia pseudotuberculosis

Bröms, Jeanette E; Edqvist, Petra; Forsberg, Åke; et al.

Characterization of the tetratricopeptide repeats in type III secretion chaperones- mediators of substrate binding and specificity

Edqvist, Petra; Bröms, Jeanette E; Steggo, Peter; et al.

A mutagenesisbased approach to map functional domain(s) within the N- terminus of Francisella tularensis IglE

Meyer, Lena; Bröms, Jeanette; Alam, A.; et al.

View publications in DiVA

Research projects

1 January 2021 until 31 December 2023

The type VI secretion system of Francisella tularensis – elucidation of its structure and assembly/disassembly control