Jan Malm is professor of Neurology, head of division and together with prof Anders Eklund leader of the hydrocephalus research group. He has about 30 years of clinical experience in the investigation and treatment of hydrocephalus. His research interest has been focused on various aspects of hydrocephalus, CSF dynamics, blood flow measurements and in recent years, the spaceflight-induced ocular syndrome (SANS) in astronauts.
Malm was principal investigator for the epidemiological study INPH-CRasH, and is currently working with VESPR, a prospective study performing MRI in 1000 elderly with gait disturbances. He is also a principal investigator in the American PENS 2 study, randomizing INPH patients to open or closed shunt. Malm has national research grants from the Swedish Heart- and Lung Foundation, the Swedish Brain foundation and the Swedish space agency. In 2020, Malm received the “Robert H. Pudenz Award” for excellence in Hydrocephalus and CSF physiology. He was also awarded the “Marmarou lecture” at the international hydrocephalus meeting in Vancouver in 2019.
Key papers (1990 – present)
1. Luciano M, Holubkov R, Williams MA, Malm J, Nagel S, Moghekar A, et al. Placebo-Controlled Effectiveness of Idiopathic Normal Pressure Hydrocephalus Shunting: A Randomized Pilot Trial. Neurosurgery. 2023;92(3):481-9.2. Wåhlin A, Holmlund P, Fellows AM, Malm J, Buckey JC, Eklund A. Optic Nerve Length before and after Spaceflight. Ophthalmology. 2021;128(2):309-16.
3. Wahlin A, Eklund A, Malm J. 4D flow MRI hemodynamic biomarkers for cerebrovascular diseases. J Intern Med. 2022;291(2):115-27.
4. Behrens A, Elgh E, Leijon G, Kristensen B, Eklund A, Malm J. The Computerized General Neuropsychological INPH Test revealed improvement in idiopathic normal pressure hydrocephalus after shunt surgery. J Neurosurg. 2020;132(3):733-40.
5. Israelsson H, Carlberg B, Wikkelso C, Laurell K, Kahlon B, Leijon G, et al. Vascular risk factors in INPH A prospective case- control study (the INPH-CRasH study). Neurology. 2017;88(6):577-85.
6. Zarrinkoob L, Ambarki K, Wahlin A, Birgander R, Eklund A, Malm J. Blood flow distribution in cerebral arteries. J Cereb Blood Flow Metab. 2015;35(4):648-54.
7. Malm J, Graff-Radford NR, Ishikawa M, Kristensen B, Leinonen V, Mori E, et al. Influence of comorbidities in idiopathic normal pressure hydrocephalus - research and clinical care. A report of the ISHCSF task force on comorbidities in INPH. Fluids Barriers CNS. 2013;10(1):22.
8. Malm J, Jacobsson J, Birgander R, Eklund A. Reference values for CSF outflow resistance and intracranial pressure in healthy elderly. Neurology. 2011;76(10):903-9.
9. Sundstrom P, Wahlin A, Ambarki K, Birgander R, Eklund A, Malm J. Venous and cerebrospinal fluid flow in multiple sclerosis: a case-control study. Ann Neurol. 2010;68(2):255-9.
10. Malm J, Kristensen B, Stegmayr B, Fagerlund M, Koskinen LO. Three-year survival and functional outcome of patients with idiopathic adult hydrocephalus syndrome. Neurology. 2000;55(4):576-8. 1.
11. Kristensen B, Malm J, Carlberg B, Stegmayr B, Backman C, Fagerlund M, et al. Epidemiology and etiology of ischemic stroke in young adults aged 18 to 44 years in Northern Sweden. Stroke. 1997;28(9):1702-9. 1.
12. Malm J, Kristensen B, Karlsson T, Fagerlund M, Elfverson J, Ekstedt J. THE PREDICTIVE VALUE OF CEREBROSPINAL-FLUID DYNAMIC TESTS IN PATIENTS WITH THE IDIOPATHIC ADULT HYDROCEPHALUS SYNDROME. Arch Neurol. 1995;52(8):783-9.
September 1, 2023: H index 39 (scopus) 37 (web of science)
Orcid no. 0000-0001-6451-1940