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Umeå University
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Staff photo Isil Keskin
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Isil Keskin

Contact

E-mail
isil.keskin@umu.se
Phone

Works at

Affiliation
Affiliated as other position at Department of Medical Biosciences Section: Pathology
Location
By 6M, Sjukhusområdet Umeå universitet, 901 85 Umeå
The motor system is exceptionally vulnerable to absence of the ubiquitously expressed superoxide dismutase-1
Brain Communications, Oxford University Press 2023, Vol. 5, (1)
Park, Julien H.; Nordström, Ulrika; Tsiakas, Konstantinos; et al.
Peripheral administration of SOD1 aggregates does not transmit pathogenic aggregation to the CNS of SOD1 transgenic mice
Acta neuropathologica communications, BioMed Central 2021, Vol. 9, (1)
Keskin, Isil; Ekhtiari Bidhendi, Elaheh; Marklund, Matthew; et al.
The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension
Acta Neuropathologica, New York: Springer 2019, Vol. 138, (1) : 85-101
Keskin, Isil; Forsgren, Elin; Lehmann, Manuela; et al.
Comprehensive analysis to explain reduced or increased SOD1 enzymatic activity in ALS patients and their relatives
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, TAYLOR & FRANCIS LTD 2017, Vol. 18, (5-6) : 457-463
Keskin, Isil; Birve, Anna; Berdynski, Mariusz; et al.
SOD, ORF and ALS: On the role of SOD1 and C9ORF72 in the pathogenesis of ALS
Umeå University medical dissertations, 1829
Keskin, Isil
Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients
PLOS ONE, Vol. 11, (2)
Keskin, Isil; Forsgren, Elin; Lange, Dale J.; et al.
Mutant superoxide dismutase-1 indistinguishable from wild-type causes ALS
Human Molecular Genetics, Vol. 21, (16) : 3568-3574
Synofzik, Matthis; Ronchi, Dario; Keskin, Isil; et al.
Enhanced protein misfolding in patient-derived models of amyotrophic lateral sclerosis
Forsgren, Elin; Lehmann, Manuela; Weygandt Mathis, Mackenzie; et al.
Comprehensive analysis to explain reduced or increased SOD1 enzymatic activity in erythrocytes in ALS patients and their relatives
Keskin, Isil; Birve, Anna; Berdynski, Mariusz; et al.
Low oxygen tension induces misfolding and aggregation of superoxide dismutase in ALS patient-derived motor neurons
Keskin, Isil; Forsgren, Elin; Andersen, Peter M.; et al.
View publications in DiVA

Research groups

Group member
ALS Research Umeå
Peter Andersen Lab