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Umeå University
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Staff photo Irina Iakovleva

Irina Iakovleva

Contact

E-mail
irina.iakovleva@umu.se
Phone
+46 90 786 93 59

Works at

Affiliation
Staff scientist at Department of Chemistry
Location
KB.E4, Linnaeus väg 10 Umeå universitet, 901 87 Umeå
Structural basis for transthyretin amyloid formation in vitreous body of the eye
Nature Communications, Nature Publishing Group 2021, Vol. 12, (1)
Iakovleva, Irina; Hall, Michael; Oelker, Melanie; et al.
Scanning electron microscopy as a tool for evaluating morphology of amyloid structures formed on surface plasmon resonance chips
Data in Brief, Elsevier 2018, Vol. 19 : 1166-1170
Brännström, Kristoffer; Gharibyan, Anna L.; Islam, Tohidul; et al.
The Properties of Amyloid-β Fibrils Are Determined by their Path of Formation
Journal of Molecular Biology, Elsevier 2018, Vol. 430, (13) : 1940-1949
Brännström, Kristoffer; Islam, Tohidul; Gharibyan, Anna L.; et al.
Transthyretin Interferes with Aβ Amyloid Formation by Redirecting Oligomeric Nuclei into Non-Amyloid Aggregates
Journal of Molecular Biology, Elsevier 2018, Vol. 430, (17) : 2722-2733
Nilsson, Lina; Pamrén, Annelie; Islam, Tohidul; et al.
Interspecies variation between fish and human transthyretins in their binding of thyroid-disrupting chemicals
Environmental Science and Technology, American Chemical Society (ACS) 2018, Vol. 52, (20) : 11865-11874
Zhang, Jin; Grundström, Christin; Brännström, Kristoffer; et al.
Selection of transthyretin amyloid inhibitors
Umeå University medical dissertations, 1826
Iakovleva, Irina
Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer
PLOS ONE, Public Library Science 2016, Vol. 11, (4)
Iakovleva, Irina; Begum, Afshan; Brännström, Kristoffer; et al.
Modifications of the 7-Hydroxyl Group of the Transthyretin Ligand Luteolin Provide Mechanistic Insights into Its Binding Properties and High Plasma Specificity
PLOS ONE, Public Library Science 2016, Vol. 11, (4)
Nilsson, Lina; Larsson, Andreas; Begum, Afshan; et al.
Structure-based Virtual Screening Protocol for in silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin
Environmental Science and Technology, Vol. 50, (21) : 11984-11993
Zhang, Jin; Begum, Afshan; Brännström, Kristoffer; et al.
The flavonoid luteolin, but not luteolin-7-o-glucoside, prevents a transthyretin mediated toxic response
PLOS ONE, Public Library Science 2015, Vol. 10, (5)
Iakovleva, Irina; Begum, Afshan; Pokrzywa, Malgorzata; et al.
Enthalpic Forces Correlate with Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma
Journal of Medicinal Chemistry, Vol. 58, (16) : 6507-6515
Iakovleva, Irina; Brännström, Kristoffer; Nilsson, Lina; et al.
A Generic Method for Design of Oligomer-Specific Antibodies
PLOS ONE, Vol. 9, (3) : e90857-
Brännström, Kristoffer; Lindhagen-Persson, Malin; Gharibyan, Anna L.; et al.
View publications in DiVA

Research groups

Group member
Elisabeth Sauer-Eriksson Lab