Helena Lindgren

Contact

helena.e.lindgren@umu.se

Works at

Staff scientist at Department of Clinical Microbiology Section: Clinical Bacteriology

6B,, Universitetssjukhuset, 22B Umeå universitet, 901 85 Umeå

Francisella tularensis-specific antibody levels in sera from Swedish patients with suspected tularemia during a 13-year period

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2024, Vol. 14

Lindgren, Helena; Liu, Xijia; Sjöstedt, Anders

Kinetics of the serological response up to one year after tularemia

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2023, Vol. 12

Lindgren, Helena; Eklund, Johan; Eneslätt, Kjell; et al.

Analyses of human immune responses to Francisella tularensis identify correlates of protection

Frontiers in Immunology, Frontiers Media S.A. 2023, Vol. 14

Lindgren, Helena; Eneslätt, Kjell; Golovliov, Igor; et al.

Utility of Borrelia-specific IgM and IgG antibody titer determinations during a 12-year period: results from a clinical laboratory in Northern Sweden

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2023, Vol. 13

Liu, Xijia; Tabibzada, Nazanin; Lindgren, Helena; et al.

Macrophages Demonstrate Guanylate-Binding Protein-Dependent and Bacterial Strain-Dependent Responses to Francisella tularensis

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2021, Vol. 11

Mohammadi, Nasibeh; Lindgren, Helena; Yamamoto, Masahiro; et al.

Vaccine-Mediated Mechanisms Controlling Francisella tularensis SCHU S4 Growth in a Rat Co-Culture System

Pathogens, MDPI 2020, Vol. 9, (5)

Lindgren, Helena; Eneslätt, Kjell; Golovliov, Igor; et al.

Guanylate-Binding Proteins Are Critical for Effective Control of Francisella tularensis Strains in a Mouse Co-Culture System of Adaptive Immunity

Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2020, Vol. 10

Mohammadi, Nasibeh; Lindgren, Helena; Golovliov, Igor; et al.

Francisella tularensis: FupA mutation contributes to fluoroquinolone resistance by increasing vesicle secretion and biofilm formation

Emerging Microbes & Infections, Taylor & Francis 2019, Vol. 8, (1)

Siebert, Claire; Lindgren, Helena; Ferre, Sabrina; et al.

Lack of OxyR and KatG Results in Extreme Susceptibility of Francisella tularensis LVS to Oxidative Stress and Marked Attenuation In vivo

Frontiers in Cellular and Infection Microbiology, Vol. 7

Honn, Marie; Lindgren, Helena; Bharath, Gurram Kumar; et al.

IFN-gamma extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection

PLoS Pathogens, Public Library Science 2017, Vol. 13, (10)

Wallet, Pierre; Benaoudia, Sacha; Mosnier, Amandine; et al.

An In Vitro Co-culture Mouse Model Demonstrates Efficient Vaccine-Mediated Control of Francisella tularensis SCHU S4 and Identifies Nitric Oxide as a Predictor of Efficacy

Frontiers in Cellular and Infection Microbiology, Vol. 6

Golovliov, Igor; Lindgren, Helena; Eneslätt, Kjell; et al.

Gallium Potentiates the Antibacterial Effect of Gentamicin against Francisella tularensis

Antimicrobial Agents and Chemotherapy, Vol. 60, (1) : 288-295

Lindgren, Helena; Sjöstedt, Anders

Roles of Reactive Oxygen Species-Degrading Enzymes of Francisella tularensis SCHU S4

Infection and Immunity, Vol. 83, (6) : 2255-2263

Binesse, Johan; Lindgren, Helena; Lindgren, Lena; et al.

Mechanisms of heme utilization by Francisella tularensis

PLOS ONE, Vol. 10, (3)

Lindgren, Helena; Lindgren, Lena; Golovliov, Igor; et al.

The Rift Valley Fever virus protein NSm and putative cellular protein interactions

Virology Journal, Vol. 9 : 139-

Engdahl, Cecilia; Näslund, Jonas; Lindgren, Lena; et al.

The role of MglA for adaptation to oxidative stress of Francisella tularensis LVS

BMC Microbiology, London: BioMed Central 2012, Vol. 12 : 14-

Honn, Marie; Lindgren, Helena; Sjöstedt, Anders

Roles for wbtC, wbtI, and kdtA genes in lipopolysaccharide biosynthesis, protein glycosylation, virulence, and immunogenicity in Francisella tularensis strain SCHU S4

Pathogens, MDPI 2012, Vol. 1, (1) : 12-29

Twine, Susan M; Vinogradov, Evguenii; Lindgren, Helena; et al.

Iron content differs between Francisella tularensis subspecies tularensis and subspecies holarctica strains and correlates to their susceptibility to H(2)O(2)-induced killing

Infection and Immunity, Vol. 79, (3) : 1218-1224

Lindgren, Helena; Honn, Marie; Salomonsson, Emelie; et al.

Administration of a donor of nitric oxide inhibits mglA expression of intracellular Francisella tularensis and counteracts phagosomal escape and subversion of TNF-α secretion

Journal of Medical Microbiology, Vol. 30, (11) : 1570-1583

Tancred, Linda; Telepnev, Maxim; Golovlev, Igor; et al.

The 58-kilodalton major virulence factor of Francisella tularensis is required for efficient utilization of iron

Infection and Immunity, Vol. 77, (10) : 4429-4436

Lindgren, Helena; Honn, Marie; Golovlev, Igor; et al.

MglA and Igl proteins contribute to the modulation of Francisella tularensis live vaccine strain-containing phagosomes in murine macrophages

Infection and Immunity, Vol. 76, (8) : 3502-3510

Bönquist, Linda; Lindgren, Helena; Golovliov, Igor; et al.

The contribution of reactive nitrogen and oxygen species to the killing of Francisella tularensis LVS by murine macrophages.

Microbes and infection, Vol. 7, (3) : 467-475

Lindgren, Helena; Stenman, Linda; Tärnvik, Arne; et al.

A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccine

Infection and Immunity, Vol. 73, (12) : 8345-8352

Twine, Susan; Byström, Mona; Chen, Wangxue; et al.

Distinct roles of reactive nitrogen and oxygen species to control infection with the facultative intracellular bacterium Francisella tularensis.

Infection and Immunity, Vol. 72, (12) : 7172-7182

Lindgren, Helena; Stenmark, Stephan; Chen, Wangxue; et al.

Infection with Francisella novicida leads to killing of murine macrophages by necrosis

Lai, Xin-He; Lindgren, Helena; Luan, Shi-Lu; et al.

T-cell-dependent and independent protection against Francisella tularensis

Stenmark, Stephan; Lindgren, Helena; Tärnvik, Arne; et al.

Inhibition of the oxidative burst by Francisella tularensis LVS is dependent on expression of MglA and the pathogenicity island proteins IglB, IglC, and IglD, but is not affected by IFN-γ

Tancred, Linda; Binesse, Johan; Lindgren, Helena; et al.

View publications in DiVA

Research groups

Group member

Anders Sjöstedt

Research projects

1 January 2021 until 31 December 2025

Development of a new tularemia vaccine