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Gunilla Olivecrona
Research qualifications:
Docent
Contact
E-mail
gunilla.olivecrona@umu.se
Phone
Works at
Affiliation
Affiliated as professor emerita at
Department of Medical Biosciences
Location
By 6M, vån 3, Sjukhusområdet
Umeå universitet, 901 87 Umeå
Publications
Publications
Research
Research
2023
Visualizing increased uptake of [18F]FDG and [18F]FTHA in kidneys from obese high-fat diet fed C57BL/6J mice using PET/CT ex vivo
PLOS ONE
, Public Library of Science (PLoS) 2023, Vol. 18
Nyrén, Rakel; Scherman, Henrik; Axelsson, Jan; et al.
2023
Role of lipoprotein lipase activity measurement in the diagnosis of familial chylomicronemia syndrome: diagnosis of the Familial Chylomicronemia Syndrome
Journal of Clinical Lipidology
, Elsevier 2023, Vol. 17, (2) : 272-280
Rioja, José; Ariza, María José; Benítez-Toledo, María José; et al.
2022
ANGPTL4 silencing via antisense oligonucleotides reduces plasma triglycerides and glucose in mice without causing lymphadenopathy
Journal of Lipid Research
, American Society for Biochemistry and Molecular Biology 2022, Vol. 63, (7)
Deng, Mingjuan; Kutrolli, Elda; Sadewasser, Anne; et al.
2022
Lipoprotein size is a main determinant for the rate of hydrolysis by exogenous LPL in human plasma
Journal of Lipid Research
, American Society for Biochemistry and Molecular Biology 2022, Vol. 63, (1)
Kovrov, Oleg; Landfors, Fredrik; Saar-Kovrov, Valeria; et al.
2020
Maternal Adipose Tissue Expansion, A Missing Link in the Prediction of Birth Weight Centile
Journal of Clinical Endocrinology and Metabolism
, Oxford University Press 2020, Vol. 105, (3) : E814-E825
Jarvie, Eleanor M.; Stewart, Frances M.; Ramsay, Jane E.; et al.
2020
Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism
Proceedings of the National Academy of Sciences of the United States of America
, National Academy of Sciences 2020, Vol. 117, (8) : 4337-4346
Kristensen, Kristian K.; Leth-Espensen, Katrine Zinck; Mertens, Haydyn D. T.; et al.
2020
Fasting induces ANGPTL4 and reduces LPL activity in human adipose tissue
Molecular Metabolism
, Elsevier 2020, Vol. 40
Ruppert, Philip M. M.; Michielsen, Charlotte C. J. R.; Hazebroek, Eric J.; et al.
2019
On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity
Journal of Lipid Research
, American Society for Biochemistry and Molecular Biology 2019, Vol. 60, (4) : 783-793
Kovrov, Oleg; Kristensen, Kristian Kølby; Larsson, Erika; et al.
2019
Lipoprotein lipase in mouse kidney: effects of nutritional status and high-fat diet
American Journal of Physiology - Renal Physiology
, American Physiological Society 2019, Vol. 316, (3) : F558-F571
Nyrén, Rakel; Makoveichuk, Elena; Malla, Sandhya; et al.
2019
Characterization of ANGPTL4 function in macrophages and adipocytes using Angptl4-knockout and Angptl4-hypomorphic mice[S]
Journal of Lipid Research
, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 2019, Vol. 60, (10) : 1741-1754
Oteng, Antwi-Boasiako; Ruppert, Philip M. M.; Boutens, Lily; et al.
2018
Decreased lipogenesis-promoting factors in adipose tissue in postmenopausal women with overweight on a Paleolithic-type diet
European Journal of Nutrition
, Springer 2018, Vol. 57, (8) : 2877-2886
Blomquist, Caroline; Chorell, Elin; Ryberg, Mats; et al.
2018
Lipoprotein Lipase Deficiency Impairs Bone Marrow Myelopoiesis and Reduces Circulating Monocyte Levels
Arteriosclerosis, Thrombosis and Vascular Biology
, Vol. 38, (3) : 509-519
Chang, Chuchun L.; Garcia-Arcos, Itsaso; Nyrén, Rakel; et al.
2018
A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase
Proceedings of the National Academy of Sciences of the United States of America
, National Academy of Sciences 2018, Vol. 115, (26) : E6020-E6029
Kristensen, Kristian K.; Midtgaard, Søren Roi; Mysling, Simon; et al.
2017
On the regulatory importance of 27-hydroxycholesterol in mouse liver
Journal of Steroid Biochemistry and Molecular Biology
, Elsevier 2017, Vol. 169 : 10-21
Heverin, Maura; Ali, Zeina; Olin, Maria; et al.
2017
High concentrations of Angiopoietin-like Protein 4 detected in serum from patients with rheumatoid arthritis can be explained by non-specific antibody reactivity
PLOS ONE
, Vol. 12, (1)
Makoveichuk, Elena; Ruge, Toralph; Nilsson, Solveig; et al.
2017
TNF-alpha decreases lipoprotein lipase activity in 3T3-L1 adipocytes by up-regulation of angiopoietin-like protein 4
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, Elsevier 2017, Vol. 1862, (5) : 533-540
Makoveichuk, Elena; Vorrsjö, Evelina; Olivecrona, Thomas; et al.
2017
Aromatic residues in the C terminus of apolipoprotein C-III mediate lipid binding and LPL inhibition
JOURNAL OF LIPID RESEARCH
, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 2017, Vol. 58, (5) : 840-852
Meyers, Nathan L.; Larsson, Mikael; Vorrsjo, Evelina; et al.
2017
Lipoprotein lipase activity and interactions studied in human plasma by isothermal titration calorimetry
Journal of Lipid Research
, Vol. 58, (1) : 279-288
Reimund, Mart; Kovrov, Oleg; Olivecrona, Gunilla; et al.
2016
Peroxisome proliferator-activated receptor activation favours selective subcutaneous lipid deposition by coordinately regulating lipoprotein lipase modulators, fatty acid transporters and lipogenic enzymes
Acta Physiologica
, Vol. 217, (3) : 227-239
Blanchard, P. G.; Turcotte, V.; Cote, M.; et al.
2016
Novel mutations in the GPIHBP1 gene identified in 2 patients with recurrent acute pancreatitis
Journal of Clinical Lipidology
, Vol. 10, (1) : 92-100
Jose Ariza, Maria; Luis Martinez-Hernandez, Pedro; Ibarretxe, Daiana; et al.
2016
Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells
The FEBS Journal
, Wiley-Blackwell 2016, Vol. 283, (13) : 2476-2493
Klinger, Stine C.; Højland, Anne; Jain, Shweta; et al.
2016
Free fatty acid transfer across the placenta facilitated by lipoprotein lipase and its relationship with fetal adiposity
British Journal of Obstetrics and Gynecology
, Vol. 123 : 86-86
McMurray, C.; Jordan, F.; Olivecrona, Gunilla; et al.
2016
The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding
eLIFE
, Vol. 5
Mysling, Simon; Kolby Kristensen, Kristian; Larsson, Mikael; et al.
2016
Diabetes and Hypertension Consistently Predict the Presence and Extent of Coronary Artery Calcification in Symptomatic Patients: A Systematic Review and Meta-Analysis
International Journal of Molecular Sciences
, Basel, Switzerland: MDPI 2016, Vol. 17, (9)
Nicoll, Rachel; Zhao, Ying; Ibrahimi, Pranvera; et al.
2016
Role of lipoprotein lipase in lipid metabolism
Current Opinion in Lipidology
, Vol. 27, (3) : 233-241
Olivecrona, Gunilla
2016
SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity
Journal of Clinical Investigation
, American Society for Clinical Investigation 2016, Vol. 126, (7) : 2706-2720
Schmidt, Vanessa; Schulz, Nadja; Yan, Xin; et al.
2016
D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile
Nature Communications
, Vol. 7
Valleix, Sophie; Verona, Guglielmo; Jourde-Chiche, Noémie; et al.
2015
TREM2 regulates microglial cell activation in response to demyelination in vivo
Acta Neuropathologica
, Vol. 129, (3) : 429-447
Cantoni, Claudia; Bollman, Bryan; Licastro, Danilo; et al.
2015
Structure-activity relationships for lipoprotein lipase agonists that lower plasma triglycerides
in vivo
European Journal of Medicinal Chemistry
, Elsevier 2015, Vol. 103 : 191-209
Caraballo, Remi; Larsson, Mikael; Nilsson, Stefan K.; et al.
2015
A Pressure-dependent Model for the Regulation of Lipoprotein Lipase by Apolipoprotein C-II
Journal of Biological Chemistry
, Bethesda: American Society for Biochemistry and Molecular Biology 2015, Vol. 290, (29) : 18029-18044
Meyers, Nathan L; Larsson, Mikael; Olivecrona, Gunilla; et al.
2015
A pressure-dependent model for the regulation of lipoprotein lipase by apolipoprotein C-II
The FASEB Journal
, Vol. 29, (Supplement 1)
Meyers, Nathan; Larsson, Mikael; Olivecrona, Gunilla; et al.
2015
Evidence for Two Distinct Binding Sites for Lipoprotein Lipase on Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1)
Journal of Biological Chemistry
, American Society for Biochemistry and Molecular Biology 2015, Vol. 290, (22) : 13919-13934
Reimund, Mart; Larsson, Mikael; Kovrov, Oleg; et al.
2015
The tissue distribution of lipoprotein lipase determines where chylomicrons bind
Journal of Lipid Research
, Vol. 56, (3) : 588-598
Savonen, Roger; Hiden, Michaela; Hultin, Magnus; et al.
2015
Acute alcohol consumption downregulates lipoprotein lipase activity
in vivo
Metabolism: Clinical and Experimental
, Elsevier 2015, Vol. 64, (11) : 1592-1596
Zemankova, Katerina; Makoveichuk, Elena; Vlasakova, Zuzana; et al.
2014
Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 111, (11) : E1043-E1052
Catoire, MilSNe; Alex, Sheril; Paraskevopulos, Nicolas; et al.
2014
Identification of a small molecule that stabilizes lipoprotein lipase
in vitro
and lowers triglycerides
in vivo
Biochemical and Biophysical Research Communications - BBRC
, Elsevier 2014, Vol. 450, (2) : 1063-1069
Larsson, Mikael; Caraballo, Rémi; Ericsson, Madelene; et al.
2014
Response of angiopoietin-like proteins 3 and 4 to haemodialysis
International Journal of Artificial Organs
, Vol. 37, (1) : 13-20
Mahmood, Dana; Makoveichuk, Elena; Nilsson, Solveig; et al.
2014
Lipoprotein lipase activity is favoured by peritoneal dialysis compared to hemodialysis
Scandinavian Journal of Clinical and Laboratory Investigation
, Vol. 74, (4) : 296-300
Mahmood, Dana; Nilsson, Solveig; Olivecrona, Gunilla; et al.
2013
Hvorfor hypertriglyseridemi fø rer til pankreatitt
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
, Den norske legeforening 2013, Vol. 133, (1) : 14-15
Christophersen, Bjørn; Sørby, Randi; Osmundsen, Harald; et al.
2013
Chronic Intermittent Hypoxia Induces Atherosclerosis via Activation of Adipose Angiopoietin-like 4
American Journal of Respiratory and Critical Care Medicine
, Vol. 188, (2) : 240-248
Drager, Luciano F.; Yao, Qiaoling; Hernandez, Karen L.; et al.
2013
Depletion of FOXP3(+) regulatory T cells promotes hypercholesterolemia and atherosclerosis
Journal of Clinical Investigation
, Vol. 123, (3) : 1323-1334
Klingenberg, Roland; Gerdes, Norbert; Badeau, Robert M; et al.
2013
Apolipoproteins C-I and C-III Inhibit Lipoprotein Lipase Activity by Displacement of the Enzyme from Lipid Droplets
Journal of Biological Chemistry
, Vol. 288, (47) : 33997-34008
Larsson, Mikael; Vorrsjö, Evelina; Talmud, Philippa; et al.
2013
Inactivation of lipoprotein lipase in 3T3-L1 adipocytes by angiopoietin-like protein 4 requires that both proteins have reached the cell surface
Biochemical and Biophysical Research Communications - BBRC
, Elsevier 2013, Vol. 441, (4) : 941-946
Makoveichuk, Elena; Vorrsjö, Evelina; Olivecrona, Thomas; et al.
2013
Fasting apolipoprotein B48 is a marker for peripheral arterial disease in type 2 diabetes
Acta Diabetologica
, Vol. 50, (3) : 383-389
Mancera-Romero, J.; Sanchez-Chaparro, M. A.; Rioja, J.; et al.
2013
Maternal Obesity Is Associated With the Formation of Small Dense LDL and Hypoadiponectinemia in the Third Trimester
Journal of Clinical Endocrinology and Metabolism
, Vol. 98, (2) : 643-652
Meyer, Barbara J.; Stewart, Frances M.; Brown, Elizabeth A.; et al.
2012
Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea
European Heart Journal
, Oxford: Oxford University Press 2012, Vol. 33, (6) : 783-U33
Drager, Luciano F.; Li, Jianguo; Shin, Mi-Kyung; et al.
2012
Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue.
BMC Physiology
, BioMed Central (BMC) 2012, Vol. 12 : 13-
Kroupa, Olessia; Vorrsjö, Evelina; Stienstra, Rinke; et al.
2012
Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury
American Journal of Physiology - Renal Physiology
, Vol. 303, (3) : F437-F448
Li, Shenyang; Nagothu, Kiran; Ranganathan, Gouri; et al.
2012
Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4 are formed
Biochemical and Biophysical Research Communications - BBRC
, San Diego: Elsevier 2012, Vol. 425, (2) : 138-143
Makoveichuk, Elena; Sukonina, Valentina; Kroupa, Olessia; et al.
2012
Triacylglycerol-rich lipoproteins protect lipoprotein lipase from inactivation by ANGPTL3 and ANGPTL4
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, Amsterdam: Elsevier 2012, Vol. 1821, (10) : 1370-1378
Nilsson, Stefan; Anderson, Fredrick; Ericsson, Madelene; et al.
View publications in DiVA
Research groups
Head of research
Gunilla Olivecrona
Research projects
28 February 2007 until 31 December 2009
Role of lipoprotein lipase for plasma lipid transport
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