Erik Lundgren

Research qualifications: Docent

Contact

erik.lundgren@umu.se

+46 70 926 20 31

Works at

Affiliated as professor emeritus at Department of Molecular Biology

6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå

Publications Publications

One mutation, two distinct disease variants: unravelling the impact of transthyretin amyloid fibril composition

Journal of Internal Medicine, Vol. 281, (4) : 337-347

Suhr, Ole B.; Lundgren, Erik; Westermark, P

Inhibition of TTR aggregation-induced cell death: a new role for serum amyloid P component

PLOS ONE, Vol. 8, (2)

Andersson, Karin; Pokrzywa, M; Dacklin, Ingrid; et al.

Inhibition of cellular FLICE-like inhibitory protein abolishes insensitivity to interferon-α in a resistant variant of the human U937 cell line

Apoptosis (London), Vol. 16, (8) : 783-794

Blomberg, Jeanette; Höglund, Andreas; Eriksson, David; et al.

Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein

Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, (14) : 5584-5589

Noborn, Fredrik; O'Callaghan, Paul; Hermansson, Erik; et al.

Uptake of aggregating transthyretin by fat body in a drosophila model for TTR-associated amyloidosis

PloS one, Vol. 5, (12) : e14343-

Pokrzywa, Malgorzata; Dacklin, Ingrid; Vestling, Monika; et al.

Transthyretin amyloidoses: new strategies for therapeutic intervention

Drugs of the future, Vol. 35, (4) : 325-332

Suhr, Ole B; Lundgren, Erik; Westermark, Per

Reduced FAS transcription in clones of U937 cells that have acquired resistance to Fas-induced apoptosis

The FEBS Journal, Vol. 276, (2) : 497-508

Blomberg, Jeanette; Ruuth, Kristina; Jacobsson, Maria; et al.

Liver Transplantation for Transthyretin Amyloidosis

Recent Advances in Transthyretin Evolution, Structure and Biological Functions, New York: Springer Berlin/Heidelberg 2009 : 239-260

Ericzon, Bo-Göran; Lundgren, Erik; Suhr, Ole B.

Antibodies to specific EBNA-1 domains and HLA DRB1*1501 interact as risk factors for multiple sclerosis.

Journal of Neuroimmunology, Vol. 215, (1-2) : 102-107

Sundström, Peter; Nyström, Maria; Ruuth, Kristina; et al.

[Interferon-alpha can improve the prognosis in high-risk melanoma. Combination of surgery, cytostatics and natural IFN-alpha doubled the survival rate.]

Läkartidningen, Läkartidningen Förlag AB 2008, Vol. 105, (6) : 358-361

Strannegård, Orian; Thorén, Fredrik B; Lundgren, Erik

Misfolded transthyretin causes behavioral changes in a Drosophila model for transthyretin-associated amyloidosis.

European Journal of Neuroscience, Vol. 26, (4) : 913-924

Pokrzywa, Malgorzata; Dacklin, Ingrid; Hultmark, Dan; et al.

Differential resistance of melanoma cells to treatment with recombinant IFN-alpha2b and leukocyte IFN.

Anticancer Res, Vol. 27, (4B) : 2109-14

Ruuth, Kristina; Berglund, Asa; Munoz, Varinia; et al.

[Swedish Animal Welfare Agency--a political threat against Swedish research]

Lakartidningen, Vol. 102, (46) : 3480-1

Lundgren, Erik

Does the cytotoxic effect of transient amyloid oligomers from common equine lysozyme in vitro imply innate amyloid toxicity?

Journal of Biological Chemistry, Vol. 280, (8) : 6269-6275

Malisauskas, Mantas; Ostman, Johan; Darinskas, Adas; et al.

The β-strand D of transthyretin trapped in two discrete conformations

Biochimica et Biophysica Acta, Amsterdam: Elsevier 2004, Vol. 1700, (1) : 93-104

Hörnberg, Andreas; Olofsson, Anders; Eneqvist, Therese; et al.

Probing solvent accessibility of transthyretin amyloid by solution NMR spectroscopy.

J Biol Chem, Vol. 279, (7) : 5699-707

Olofsson, Anders; Ippel, Johannes H; Wijmenga, Sybren S; et al.

Gene therapy: lessons learned from liver transplantation for transthyretin-amyloidosis.

Liver Transpl, Vol. 10, (12) : 1551-3

Suhr, Ole B; Holmgren, Gösta; Lundgren, Erik

Only amyloidogenic inermediates of transthyretin induce apoptosis

Biochemical and Biophysical Research Communications - BBRC, Carolina Academic Press 2002, Vol. 294, (2) : 309-314

Andersson, Karin; Olofsson, Anders; Holm Nielsen, Ellen; et al.

Disulfide-bond formation in the transthyretin mutant Y114C prevents amyloid fibril formation in vivo and in vitro.

Biochemistry, Vol. 41, (44) : 13143-51

Eneqvist, Therese; Olofsson, Anders; Ando, Yukio; et al.

Interferon-alpha promotes survival of human primary B-lymphocytes via phoshatidylinositol 3-kinase

Biochemical and Biophysical Research Communications - BBRC, Academic Press 2001, Vol. 284, (3) : 583-586

Ruuth, Kristina; Carlsson, Lennart; Hallberg, Bengt; et al.

The beta-slip: a novel concept in transthyretin amyloidosis.

Mol Cell, Vol. 6, (5) : 1207-18

Eneqvist, Therese; Andersson, Karin; Olofsson, Anders; et al.

A comparative analysis of 23 structures of the amyloidogenic protein transthyretin.

J Mol Biol, Vol. 302, (3) : 649-69

Hörnberg, Andreas; Eneqvist, Therese; Olofsson, Anders; et al.

Exposure of cryptic epitopes on transthyretin only in amyloid and in amyloidogenic mutants

Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 1999, Vol. 96, (6) : 3108-3113

Goldsteins, Gundars; Persson, Håkan; Andersson, Karin; et al.

Characterisation of two highly amyloidogenic mutants of transthyretin

Biochemistry, American Chemical Society (ACS) 1997, Vol. 36, (18) : 5346-5352

Goldsteins, Gundars; Andersson, Karin; Olofsson, Anders; et al.

Amino acid naphthylamidase isozymes in human cells grown in vitro: Hormonal regulation and isozyme differentiation in cancer cells and normal cells

Umeå University medical dissertations, 1

Lundgren, Erik

IFN-alpha induced proliferation of human primary B-lymphocytes

Carlsson, Lennart; Ruuth, Kristina; Lundgren, Erik

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