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Umeå University
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Staff photo Elin Chorell

Elin Chorell

My research is focused on identifying mechanisms the underlie development and remission of typ 2 diabetes.

Research qualifications: Docent

Contact

E-mail
elin.chorell@umu.se
Phone
+46 90 785 13 26

Works at

Affiliation
Associate professor at Department of Public Health and Clinical Medicine Section: Endocrinology and diabetes
Location
Visiting address, view map
Myofiber-specific lipidomics unveil differential contributions to insulin sensitivity in individuals of African and European ancestry
Heliyon, Elsevier 2024, Vol. 10, (12)
Eurén, Tova; Gower, Barbara; Steneberg, Pär; et al.
Genetic mimicry analysis reveals the specific lipases targeted by the ANGPTL3-ANGPTL8 complex and ANGPTL4
Journal of Lipid Research, Elsevier 2023, Vol. 64, (1)
Landfors, Fredrik; Chorell, Elin; Kersten, Sander
Leukotriene A4 Hydrolase and Hepatocyte Growth Factor Are Risk Factors of Sudden Cardiac Death Due to First-Ever Myocardial Infarction
International Journal of Molecular Sciences, MDPI 2022, Vol. 23, (18)
Landfors, Fredrik; Vikström, Simon; Wennberg, Patrik; et al.
Lysophospholipids as Predictive Markers of ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI)
Metabolites, MDPI 2021, Vol. 11, (1)
Chorell, Elin; Olsson, Tommy; Jansson, Jan-Håkan; et al.
Improved peripheral and hepatic insulin sensitivity after lifestyle interventions in type 2 diabetes is associated with specific metabolomic and lipidomic signatures in skeletal muscle and plasma
Metabolites, MDPI 2021, Vol. 11, (12)
Chorell, Elin; Otten, Julia; Stomby, Andreas; et al.
Fatty Acid Metabolism and Associations with Insulin Sensitivity Differs Between Black and White South African Women
Journal of Clinical Endocrinology and Metabolism, Endocrine Society 2021, Vol. 106, (1) : E140-E151
Goedecke, Julia H.; Chorell, Elin; van Jaarsveld, Paul J.; et al.
Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity
Diabetologia, Springer 2021, Vol. 64, (7) : 1642-1659
Mendham, Amy E.; Goedecke, Julia H.; Zeng, Yingxu; et al.
The liver-alpha-cell axis after a mixed meal and during weight loss in type 2 diabetes
Endocrine Connections, Bioscientifica 2021, Vol. 10, (9) : 1101-1110
Otten, Julia; Stomby, Andreas; Waling, Maria; et al.
Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes
Diabetologia, Springer 2021, Vol. 64, (9) : 2077-2091
Sjögren, Rasmus J. O.; Rizo-Roca, David; Chibalin, Alexander V.; et al.
Metabolic Profiling of Plasma in Patients with Irritable Bowel Syndrome after a 4-Week Starch- and Sucrose-Reduced Diet
Metabolites, MDPI 2021, Vol. 11, (7)
Stenlund, Hans; Nilholm, Clara; Chorell, Elin; et al.
Walking Time Is associated With Hippocampal Volume in Overweight and Obese Office Workers
Frontiers in Human Neuroscience, Frontiers Media S.A. 2020, Vol. 14
Bergman, Frida; Matsson-Frost, Tove; Jonasson, Lars S.; et al.
Circulating and Adipose Tissue Fatty Acid Composition in Black South African Women with Obesity: A Cross-Sectional Study
Nutrients, MDPI 2020, Vol. 12, (6)
Nankam, Pamela A. Nono; van Jaarsveld, Paul J.; Chorell, Elin; et al.
Fat redistribution and accumulation of visceral adipose tissue predicts type 2 diabetes risk in middle-aged black South African women: a 13-year longitudinal study
Nutrition & Diabetes, Nature Publishing Group 2019, Vol. 9
Mtintsilana, Asanda; Micklesfield, Lisa K.; Chorell, Elin; et al.
Adiposity Mediates the Association between the Dietary Inflammatory Index and Markers of Type 2 Diabetes Risk in Middle-Aged Black South African Women
Nutrients, MDPI 2019, Vol. 11, (6)
Mtintsilana, Asanda; Micklesfield, Lisa K.; Chorell, Elin; et al.
Postprandial levels of GLP-1, GIP, and glucagon after two years of weight loss with a Paleolithic diet: a randomized controlled trial in healthy obese women
European Journal of Endocrinology, Bioscientifica 2019, Vol. 180, (6) : 417-427
Otten, Julia; Ryberg, Mats; Mellberg, Caroline; et al.
Alterations in the metabolism of phospholipids, bile acids and branched-chain amino acids predicts development of type 2 diabetes in black South African women: a prospective cohort study
Metabolism: Clinical and Experimental, Elsevier 2019, Vol. 95 : 57-64
Zeng, Yingxu; Mtintsilana, Asanda; Goedecke, Julia H.; et al.
Decreased lipogenesis-promoting factors in adipose tissue in postmenopausal women with overweight on a Paleolithic-type diet
European Journal of Nutrition, Springer 2018, Vol. 57, (8) : 2877-2886
Blomquist, Caroline; Chorell, Elin; Ryberg, Mats; et al.
An Exercise Intervention to Unravel the Mechanisms Underlying Insulin Resistance in a Cohort of Black South African Women: Protocol for a Randomized Controlled Trial and Baseline Characteristics of Participants
JMIR Research Protocols, JMIR PUBLICATIONS, INC 2018, Vol. 7, (4)
Goedecke, Julia H.; Mendham, Amy E.; Clamp, Louise; et al.
Attenuated Low-Grade Inflammation Following Long-Term Dietary Intervention in Postmenopausal Women with Obesity
Obesity, Vol. 25, (5) : 892-900
Blomquist, Caroline; Alvehus, Malin; Burén, Jonas; et al.
Pregnancy to postpartum transition of serum metabolites in women with gestational diabetes
Metabolism: Clinical and Experimental, Saunders Elsevier 2017, Vol. 72 : 27-36
Chorell, Elin; Hall, Ulrika Andersson; Gustavsson, Carolina; et al.
Plasma metabolomic response to postmenopausal weight loss induced by different diets
Metabolomics, Springer 2016, Vol. 12, (5)
Chorell, Elin; Ryberg, Mats; Larsson, Christel; et al.
Obesity-related metabolite profiles of black women spanning the epidemiologic transition
Metabolomics, New York: Springer-Verlag New York 2016, Vol. 12, (3)
Dugas, Lara R.; Chorell, Elin; Plange-Rhule, Jacob; et al.
Glucocorticoid receptor gene expression in adipose tissue and associated metabolic risk in black and white South African women
International Journal of Obesity, Vol. 39, (2) : 303-311
Goedecke, J H; Chorell, Elin; Livingstone, D E W; et al.
Constrained randomization and multivariate effect projections improve information extraction and biomarker pattern discovery in metabolomics studies involving dependent samples
Metabolomics, Springer 2015, Vol. 11, (6) : 1667-1678
Jonsson, Pär; Wuolikainen, Anna; Thysell, Elin; et al.
Development and optimization of simple one-step methods for the synthesis of 4-amino-substituted 1,8-naphthalimides
European Journal of Organic Chemistry, (28) : 6175-6182
Kindahl, Tomas; Chorell, Elin; Chorell, Erik
Ökat om­vårdnadsbehov främsta orsak till lång vårdtid på medicinklinik: Retrospektiv journalstudie styrker att tidig vårdplanering skulle kunna ge bättre platstillgång
Läkartidningen, Vol. 111, (6) : 219-222
Skärby, Rut; Chorell, Elin; Karling, Pontus
Impact of probiotic feeding during weaning on the serum lipid profile and plasma metabolome in infants
British Journal of Nutrition, Cambridge University Press 2013, Vol. 110, (1) : 116-126
Chorell, Elin; Videhult, Frida Karlsson; Hernell, Olle; et al.
Efficient Synthesis of 2-Substituted Phthalimides from Phthalic Acids in One Step
European Journal of Organic Chemistry, Wiley-VCH Verlagsgesellschaft 2013, Vol. 2013, (33) : 7512-7516
Chorell, Erik; Chorell, Elin
Physical fitness level is reflected by alterations in the human plasma metabolome
Molecular BioSystems, Royal Society of Chemistry 2012, Vol. 8, (4) : 1187-1196
Chorell, Elin; Svensson, Michael; Moritz, Thomas; et al.
Validated and Predictive Processing of Gas Chromatography-Mass Spectrometry Based Metabolomics Data for Large Scale Screening Studies, Diagnostics and Metabolite Pattern Verification
Metabolites, Basel: MDPI 2012, Vol. 2 : 796-817
Thysell, Elin; Chorell, Elin; Svensson, Michael B; et al.
Validated and predictive processing of gas chromatography-mass spectra screening studies, diagnostics and metabolite pattern verification
Metabolites, M D P I AG 2012, Vol. 2, (4) : 796-817
Thysell, Elin; Chorell, Elin; Svensson, Michael; et al.
Mapping the consequenses of physical exercise and nutrition on human health: A predictive metabolomics approach
Umeå: Print och Media 2011
Chorell, Elin
A predictive metabolomics evaluation of nutrition-modulated metabolic stress responses in human blood serum during the early recovery phase of strenuous physical exercise
Journal of Proteome Research, Washington: American Chemical Society 2009, Vol. 8, (6) : 2966-77
Chorell, Elin; Moritz, Thomas; Branth, Stefan; et al.
A Multivariate Screening Strategy for Investigating Metabolic Effects of Strenuous Physical Exercise in Human Serum
Journal of Proteome Research, American Chemical Society 2007, Vol. 6, (6) : 2113-2120
Chorell, Elin; Thysell, Elin; Jonsson, Pär; et al.
Reliable Profile Detection in Comparative Metabolomics
Omics, Mary Ann Liebert 2007, Vol. 11, (2) : 209-224
Thysell, Elin; Pohjanen, Elin; Lindberg, Johan; et al.
Statistical multivariate metabolite profiling for aiding biomarker pattern detection and mechanistic interpretations in GC/MS based metabolomics
Metabolomics, Vol. 2, (4) : 257-68
Chorell, Elin; Thysell, Elin; Lindberg, Johan; et al.
Installing treadmill workstations in offices does little for cognitive performance and brain structure, despite a baseline association between sitting time and hippocampus volume
Bergman, Frida; Mattson-Frost, Tove; Jonasson, Lars; et al.
Long-term effects of a Paleolithic diet on plasma fatty acid composition in postmenopausal women with obesity: a randomized trial
Blomquist, Caroline; Chorell, Elin; Ryberg, Mats; et al.
The impact of feeding Lactobacillus F19 during weaning: a study of the plasma metabolome
Chorell, Elin; Antti, Henrik; Karlsson, Frida; et al.
A metabolomic evaluation of short and long term effects of different macronutrient intake in overweight and obese postmenopausal women
Chorell, Elin; Rydberg, Mats; Larsson, Christel; et al.
Processing of mass spectrometry based metabolomics data for large scale screening studies and diagnostics
Thysell, Elin; Chorell, Elin; Svensson, Michael B.; et al.
View publications in DiVA

Research projects

31 August 2022 until 31 December 2028
Remission of type 2 diabetes becomes possible through eHealth
1 January 2015
What happens to the human body when adhering to a ketogenic diet? A randomised controlled trial
29 April 2013 until 31 December 2027
VIPVIZA

My main teaching is in the area of molecular metabolism, lipid metabolism and multivariate bioinformatics.