Cecilia Hedenström Lindgren

Contact

cecilia.lindgren@umu.se

+46 90 786 93 69

Works at

Staff scientist at Department of Chemistry

KBC, Linnaeus väg 10, C4-33-07 Umeå universitet, 901 87 Umeå

Enzyme dynamics determine the potency and selectivity of inhibitors targeting disease-transmitting mosquitoes

ACS - Infectious Diseases, American Chemical Society (ACS) 2024, Vol. 10, (10) : 3664-3680

Kumari, Rashmi; Lindgren, Cecilia; Kumar, Rajendra; et al.

Structure-function study of a Ca²⁺-independent metacaspase involved in lateral root emergence

Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the National Academy of Sciences (PNAS) 2023, Vol. 120, (22)

Stael, Simon; Sabljić, Igor; Audenaert, Dominique; et al.

A highly substituted ring-fused 2-pyridone compound targeting PrfA and the efflux regulator BrtA in listeria monocytogenes

mBio, American Society for Microbiology 2023, Vol. 14, (3)

Tükenmez, Hasan; Singh, Pardeep; Sarkar, Souvik; et al.

Structure-activity relationships reveal beneficial selectivity profiles of inhibitors targeting acetylcholinesterase of disease-transmitting mosquitoes

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2023, Vol. 66, (9) : 6333-6353

Vidal-Albalat, Andreu; Kindahl, Tomas; Rajeshwari, Rajeshwari; et al.

Broad-Spectrum Antidote Discovery by Untangling the Reactivation Mechanism of Nerve-Agent-Inhibited Acetylcholinesterase

Chemistry - A European Journal, John Wiley & Sons 2022, Vol. 28, (40)

Lindgren, Cecilia; Forsgren, Nina; Hoster, Norman; et al.

Noncovalent Inhibitors of Mosquito Acetylcholinesterase 1 with Resistance-Breaking Potency

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2018, Vol. 61, (23) : 10545-10557

Knutsson, Sofie; Engdahl, Cecilia; Kumari, Rashmi; et al.

Dynamics Determine Signaling in a Multicomponent System Associated with Rheumatoid Arthritis

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2018, Vol. 61, (11) : 4774-4790

Lindgren, Cecilia; Tyagi, Mohit; Viljanen, Johan; et al.

Design strategies for new drugs targeting multicomponent systems: focusing on class II MHC proteins and acetylcholinesterase

Umeå: Umeå universitet 2017

Lindgren, Cecilia

Benefits of statistical molecular design, covariance analysis, and reference models in QSAR: a case study on acetylcholinesterase

Journal of Computer-Aided Molecular Design, Vol. 29, (3) : 199-215

Andersson, C. David; Hillgren, J. Mikael; Lindgren, Cecilia; et al.

Hydroxyethylene isosteres introduced in type II collagen fragments substantially alter the structure and dynamics of class II MHC A(q)/glycopeptide complexes

Organic and biomolecular chemistry, Vol. 13, (22) : 6203-6216

Lindgren, Cecilia; Andersson, Ida E.; Berg, Lotta; et al.

Design of Reactive Drugs: Structure and Mechanism of Novel Nerve Agent Antidotes

Lindgren, Cecilia; Forsgren, Nina; Akfur, Christine; et al.

Modification of a Fragment from Type II Collagen Affects the Dynamics of Human Class II MHC Proteins and the Subsequent T-Cell Response, Associated with Rheumatoid Arthritis

Lindgren, Cecilia; Tyagi, Mohit; Viljanen, Johan; et al.

Hydrophobic recognition allows transcription factor PrfA from Listeria monocytogenes to bind peptides of different sequences and lengths

Oelker, Melanie; Lindgren, Cecilia; Grundström, Christin; et al.

Discovery of three new binding sites and modes of ring-fused 2-pyridones to PrfA: How can they contribute to drug design?

Oelker, Melanie; Vielfort, Katarina; Lindgren, Cecilia; et al.

Discovery of inhibitors and activators targeting metacaspases of the parasite Trypanosoma brucei

Rajeshwari, Rajeshwari; Boström, Emelie; Lindgren, Cecilia; et al.

Potent and selective indole-based inhibitors targeting disease-transmitting mosquitoes

Rajeshwari, Rajeshwari; Lindgren, Cecilia; Duvauchelle, Valentine; et al.

Exploring acetylcholinesterase of honey bees: how to avoid off-target effects of insecticides

Rajeshwari, Rajeshwari; Lindgren, Cecilia; Springer Engdahl, Cecilia; et al.

View publications in DiVA

Research groups

Group member

Anna Linusson Lab