Research group
In Tomas Gustafsson lab, we mainly focus on two different themes; clinical infectious disease research on the topic of tularemia and translational research in the area of antibiotic development against gonorrhoeae.
Tularemia is a rare infection which is caused by the bacterium Francisella tularensis. It is characterized by general symptoms in the form of high fever and flu-like symptoms as well as specific symptom related to the clinical form of the disease – often persistent ulcers and swollen lymph-nodes. Tularemia is unusually common in the northern parts of Sweden which the highest incidence areas in the world. This sets us up for a unique opportunity to design high quality studies of this unpredictable and rare disease. Our main research questions are listed below:
Can we improve diagnostics of tularemia and can we develop a clinical scoring system to aid clinicians?
What is the best treatment of tularemia?
What does tularemia cost – for the patients and for the society?
Can we predict outbreaks of tularemia before they occur?
Which vectors are important for transmission of tularemia?
The antibiotic development studies mainly focus on how we can bridge gaps in the antibiotic development pipeline against Neisseria gonorrhoeae – the causative agent behind gonorrhoeae which is the second most common sexually transmitted disease.