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Image: David Fisher

Martin Cohn group

Research group Maintenance of genomic stability and DNA repair in humans.

Welcome to the Cohn group webpage!

Our laboratory is interested in understanding how the various DNA repair pathways function in human cells. Our work has led to the discovery of novel proteins participating in DNA repair pathways, such as the Fanconi Anemia DNA repair pathway. Interestingly, our findings demonstrate that these proteins often function as part of large multisubunit protein complexes. Using a combination of molecular and cell biology, live-cell imaging, biochemistry, CRISPR/Cas9 genome engineering and cryo-EM, we are continuing to identify and study new proteins playing key roles in human DNA repair pathways.

We are an interactive and dynamic group of people. Cohn laboratory alumni are successful in securing positions as group leaders and post-docs at top institutions as well as leading positions in industry. Read on to explore our research and see who our current group members are.

Publications

Cell Reports, Cell Press 2024, Vol. 43, (11)
Yang, Di; Bai, Fengxiang; Lopez Martinez, David; et al.
Cell Reports, Cell Press 2023, Vol. 42, (7)
Kupculak, Marian; Bai, Fengxiang; Luo, Qiang; et al.
STAR protocols, Elsevier 2021, Vol. 2, (1)
Liang, Chih-Chao; Cohn, Martin A.
Cell Reports, Elsevier 2020, Vol. 32, (7)
Socha, Anna; Yang, Di; Bulsiewicz, Alicja; et al.
Nucleic Acids Research, Oxford University Press 2019, Vol. 47, (21) : 11268-11283
Cipolla, Lina; Bertoletti, Federica; Maffia, Antonio; et al.
Cell Reports, Elsevier 2019, Vol. 27, (10) : 2990-3005.e5.
Lopez-Martinez, David; Kupculak, Marian; Yang, Di; et al.
PLOS Genetics, Public Library of Science (PLoS) 2018, Vol. 14, (10)
Motnenko, Anna; Liang, Chih-Chao; Yang, Di; et al.

 

Head of research

Martin Cohn
Associate professor
E-mail
Email

Overview

Participating departments and units at Umeå University

Department of Molecular Biology

Research area

Cancer, Molecular biology and genetics, Molecular medicine
Latest update: 2024-10-15