Research group We investigate how prediabetes and type 2 diabetes develops and conduct clinical studies to treat and reverse those diseases.
We conduct clinical studies in which the treatment consists of weight loss, physical activity or dietary changes. The goal of our studies is to treat type 2 diabetes or to achieve diabetes remission.
In type 2 diabetes, not only insulin sensitivity and insulin secretion are affected, but several other hormones such as glucagon and incretins. We investigate whether those hormonal abnormalities are reversible.
Using epidemiological studies, we examine the development of prediabetes, which later often leads to type 2 diabetes and cardiovascular disease. We are particularly interested in how metabolism is affected by changes in insulin sensitivity and insulin secretion.
Impaired lung function is an unknown complication of type 2 diabetes which we investigate in epidemiological studies and in a clinical trial.
