Image: Mattias Pettersson
Research group Our group aims at integrating all known and hypothesized regulatory mechanisms about T cells in a single predictive model.
Our research group tries to understand how T cells function, in health and disease. T cells are particularly important against cancer, and genetically modified T cells (CAR T cells) is a promising therapy. We use our maps of gene regulation to develop new ways of programming T cells to fight diseases such as cancer.
To our aid we use modern unbiased measurement methods ("multi-omics" and single-cell) that helps us to collect large amounts of information without deciding in advance which genes we should look at. As such we hope to obtain insights not possible with traditional targeted methods. Furthermore we use modern synthetic biology such as the CRISPR-Cas9 technology to reprogram genes, to be able to tell in detail how they function. We hope the genes we discover will be the key to hard-to-cure diseases such as cancer.
For more information, see our external website and the MIMS website
Improved resolution promotes advanced cell analysis, especially in cases of abnormal cell division in cancer.
Some people naturally have higher levels of proteins that protect them from covid-19.
Cancer research at Umeå University receive SEK 59.5 million in the Swedish Cancer Society's allocation.
