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Antimicrobial resistance

Umeå University has a long tradition of research within the field of antimicrobial resistance including basic research that aims to understand the virulence mechanisms of microorganisms and the interaction between the host and microorganisms. More applied research is also conducted that seeks new solutions to combat the problem, for example through the development of new molecules that are effective against resistant bacteria, viruses, fungi and parasites.

Antimicrobial resistance is a global public health problem that is increasing at an alarming rate. Today, about 700,000 people worldwide die each year due to infections caused by antibiotic-resistant bacteria. If nothing is done, 10 million people are at risk of dying from infections caused by resistant microorganisms by 2050.

Today's healthcare is completely dependent on effective antimicrobial agents, for example in connection with cancer treatment, operations and transplants. If resistance development is not slowed down, previously harmless infections or simple surgical procedures risk a fatal outcome in the future.

Features

Några personer som står bredvid varandra
Students found few resistant bacteria at Open house

Collected samples from the visitor's hands and everyday objects.

Fredrik Almqvist, kemi
Promising results for new antibiotic against "flesh-eating" illnesses

Effective against serious infections, according to new study.

Elektronmikroskopbild på gula prickar på blå botten
Degradation of cell wall key in the spread of resistance

New study shows how an enzyme breaks down the bacteria's cell wall to transfer resistance to antibiotics.

Porträtt på Felipe Cava, universitetslektor vid Institutionen för molekylärbiologi, Umeå universitet.
New antibiotics in sight after discovery

Felipe Cava, Umeå University, is one of the researchers that have identified a bacterial enzyme.

Movements in proteins inform about antibiotic resistance spreading

Researchers at Umeå University have discovered how a certain type of protein moves for DNA to be copied.

New transporter for recycling of bacterial cell wall found

A transporter which some bacteria use to recycle fragments of their cell wall has been discovered in Umeå,

New potential target proteins for novel antibiotics discovered

Felipe Cava's group has discovered proteins needed to maintain the bacteria's cell wall structure.

South African expert lectures on antibiotic resistance in aquatic environments

The collaboration with the researcher started through the South Africa - Sweden University Forum, SASUF.

"Antibiotic resistance can affect anyone"

Public health student Erick Venant explains why World Antimicrobial Awareness Week is important to him.

New class of antibiotics against resistant bacteria

Umeå researchers one step closer to a new weapon against multidrug-resistant bacteria.

How antibiotic-resistant bacteria gain their ability to adhere

Infection researchers show in Nature structure and mechanism of bacterium A. baumannii attaching pilis.

Antibiotics increase the risk of colon cancer

A clear link between taking antibiotics and increased risk of colon cancer has been found by researchers.

Umeå researchers in major US initiative to combat antibiotic resistance

Fredrik Almqvist's research group assists with design and synthesis of new antibacterial substances.

A new way to uncover targets for future antibiotics

Maria Fällman and Kemal Avican made their idea into a interdisciplinary project together with Icelab.

A new brick in the wall: bacterial cell wall intermediate found

Intermediate of the peptidoglycan recycling pathway that can modulate synthesis and structure of cell wall.

The aim is to develop new antibiotics

Felipe Cava wants to learn more about the small and complex microbes.

Research groups

Åsa Gylfe Lab
We research about novel antibacterial strategies for treatment of Chlamydia.
Type of project Research group
Bernt Eric Uhlin Lab
Bacterial fitness mechanisms of the versatile pathogenic variants of Escherichia coli and the emerging opportunistic pathogen Acinetobacter...
Type of project Forskargrupp
Felipe Cava Group
Bacterial cell wall composition and its contribution to long-standing and emerging infectious diseases.
Type of project Research group
Fredrik Almqvist Lab
Our group focus on method development in organic synthesis and design and synthesis of molecules to be used for treatment of infectious and...
Type of project Research group
Ignacio Mir-Sanchis Lab
Our group studies antimicrobial resistance - phage therapy.
Type of project Research group
Johan Normark lab
Our research is about host immunological and metabolomic responses to acute infections and vaccination.
Type of project Research group
Johan Trygg - Chemometrics Lab
Advanced data analytics in life science is becoming a core element in modern data driven life science research. Our research focus on data from...
Type of project Research group
Jörgen Johansson Lab
Our group study stress regulatory mechanisms and RNA-mediated regulation in the bacterial pathogen Listeria monocytogen.
Type of project Research group
Jürgen Schleucher Lab
We have a biophysical approach to study both proteins and nucleic acids and tree rings in relation to climate change.
Type of project Research group
Laura Carroll Lab
We develop and utilize bioinformatic approaches to monitor and combat the spread of bacterial pathogens.
Type of project Research group
Magnus Evander Lab
We study viruses that are transmitted from animals or mosquitoes. Also, we develop antiviral drugs.
Type of project Research group
Niklas Arnberg Lab
The overall purpose of our research is to identify molecules and mechanisms that viruses need to bind to and enter host cells. This is of importanc...
Type of project Forskargrupp
Ronnie Berntsson Lab
The group studies structural biology of type 4 secretion systems.
Type of project Research group
Tomas Gustafsson lab
text is coming soon
Type of project Research group