NEWS Ultrasound, a non-invasive technique commonly used to study the presence of atherosclerosis disease in blood vessels, can be used to identify patients at increased risk of future stroke who could benefit from surgery. Since surgical treatment to prevent stroke is only considered beneficial to some, ultrasound can prove useful in preventing unnecessary surgical intervention, new research at Umeå University shows.
Atherosclerosis, or hardening of the arteries, is an inflammatory disease affecting the arteries supplying the brain, heart, other organs and extremities with oxygen-rich blood. A well-established atherosclerosis disease, with accumulation of plaque narrowing the arteries, can obstruct the blood supply to the brain and other vital organs. Atherosclerosis in the neck arteries can cause stroke. The serious condition, known as carotid stenosis, is quite common in the elderly as well as in people with risk factors such as hypertension, smoking, diabetes, hypercholesterolemia and obesity.
Atherosclerosis disease progression can be controlled by medical treatment including cholesterol-lowering drugs, and significant narrowing in symptomatic patients can be treated surgically.
“We know that preventive surgical treatment of carotid stenosis is only beneficial for a small subgroup, and that most asymptomatic patients will do better with only medical therapy. By using ultrasound, we can identify the patients who are at a higher risk of stroke and thus would benefit from surgery. But preventing unnecessary surgical intervention in most cases is equally important,” says Fisnik Jashari, doctoral student at the Department of Public Health and Clinical Medicine and author of the dissertation.
To assess the nature of atherosclerosis disease and the extent of plaque build-up, the non-invasive ultrasound method remains favoured over most others because it is radiation free, cheap and patient-friendly.
Fisnik Jashari comes from Prishtina in Kosovo, where he works as resident doctor in Neurology. He is a doctoral student in the Department of Public Health and Clinical Medicine at Umeå University.
The dissertation has been published digitally
Fisnik Jashari, Department of Public Health and Clinical Medicine, Umeå UniversityPhone: +46 90 785 00 00, +37 744 19 47 92
Email: fisnik.jashari@medicin.umu.se
On Thursday 26 November, Fisnik Jashari, Department of Public Health and Clinical Medicine, defends his dissertation entitled: Carotid artery disease: plaque features and vulnerability. Opponent: Christine Kremer, Department of Clinical Sciences at Lund University. Main supervisor: Michael Henein, professor at the Department of Public Health and Clinical Medicine.
The public defence of the dissertation will take place at 09:00 at the University Hospital of Umeå (NUS), Unod T9, Room D.
Editor: Anna Lawrence