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Syllabus:

Theory of Molecular Biology and Human Genetics, 12 Credits

The course is discontinued from 2023-06-06

Swedish name: Teori i molekylär biologi och human genetik

This syllabus is valid: 2011-01-24 and until further notice

Course code: 5MO025

Credit points: 12

Education level: Second cycle

Main Field of Study and progress level: Molecular Biology: Second cycle, has only first-cycle course/s as entry requirements
Pharmacy: Second cycle, has only first-cycle course/s as entry requirements

Grading scale: Three-grade scale

Responsible department: Department of Molecular Biology

Revised by: Faculty Board of Science and Technology, 2023-06-06

Contents

The course is divided into two parts: molecular genetics 4,5 ECTS and human genetics 7,5 ECTS. Both consist of theoretical sections. Part 1 (molecular genetics) focuses on molecular biology using E. coli as a model system. The focus will be on genome organization, DNA replication and repair, cell cycle as well as the regulation of transcription, translation and growth. During this part students will also learn about bacterial viruses, transposons, plasmids and the analysis of recombination, genetic exchange and mutations. Part 2 (human genetics) focuses on mechanisms and factors that influence inheritance in humans; from the organization of the genetic material, its packaging into gametes and developmental processes to population structure and environmental factors. Included are also genetic diseases, pharmacogenetics, cancer, model organisms, genomics and techniques such as gene testing and gene therapy.

Expected learning outcomes

After the course the student is expected to: - show extended knowledge on molecular genetics theory - know how to apply fundamental principles of genetic analysis in both haploid and diploid organisms - be able to analyze and evaluate genetics and molecular genetics experiments - be able to describe how the hereditary material is inherited, mapped, analyzed and identified - understand why studies of genetic diseases need to take environmental factors and the variation in the population into account - understand how model organisms such as the fruit fly can be used to study aspects of human genetics - be familiar with techniques such as genetic screening and gene therapy as well as be able to discuss their potential benefits and problems - be able to write and critically evaluate scientific reports - be able to use and understand basic statistical tools

Required Knowledge

Proficiency in English equivalent to Swedish upper secondary course English A (IELTS (Academic) with a minimum overall score of 5.5 and no individual score below 5.0. TOEFL PBT (Paper-based Test) with a minimum total score of 530 and a minimum TWE score of 4. TOEFL iBT (Internet-based Test) with a minimum total score of 72 and a minimum score of 17 on the Writing Section). For admission to the course a bachelor degree in pharmacy, including 90 ECTS pharmaceutics and pharmaceutical chemistry 30 ECTS, or 180 ECTS pharmacy degree or equivalent, are required. The eligibility requirements are also met by a bachelor's degree in molecular biology with at least 30 credits pharmaceutical chemistry and 30 credits biomedical science or equivalent.

Form of instruction

The course is internet based and consists of lectures, self studies, project works with written reports, problem solving. Project works will be done in groups and should be presented both as written reports with references and orally presented to the other project groups who will evaluate the work. Mandatory parts of the course are written reports and exam.

Literature

The literature list is not available through the web. Please contact the faculty.