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Syllabus:

Chromatography, 15 Credits

The course is discontinued from 2021-08-09

Swedish name: Kromatografi

This syllabus is valid: 2009-08-24 valid to 2011-09-04 (newer version of the syllabus exists)

Course code: 5KE083

Credit points: 15

Education level: Second cycle

Main Field of Study and progress level: Chemistry: Second cycle, in-depth level of the course cannot be classified

Grading scale: Pass with distinction, Pass, Fail

Responsible department: Department of Chemistry

Contents

The initial theoretical part of the course deals with the thermodynamic, kinetic, and flow dynamic prerequisites for successful analytical separations using various forms of chromatography and differential migration techniques. This section is followed by a treatment of the different forms of analytical gas and liquid chromatography (including supercritical chromatography), analytical electrophoretic methods, and membrane-based separation methods for analytical purposes. Sample preparation by the aid of various physical and chemical separation principles are also taught in this part of the course. Special emphasis is put on aspects that enable the choice of “correct” separation and detection techniques for a particular analytical problem. Much attention is paid to detection, since sensitive and selective analytical methods are dependent on the possibilities for detecting and positively identifying the separated compounds. Chemical methods for separation- and detection-oriented derivatization are also dealt with in this section. The theoretical part of the course ends with a discussion of the working procedures for validation of developed methods, with examples from the pharmaceutical industry.

Required Knowledge

Analytical Chemistry (15 ECTS, 5KE082/5KE081), or the equivalent. English proficiency equivalent to IELTS Academic Training - minimum score 5.0 with no individual score below 4.5 (tests taken before January 2005 not admissible), or TOEFL - minimum score 500 on paper based test and not below 4.0 on the TWE, alternatively 173 on computer based test with iBT61 is also required as well as basic entrance requirements for higher studies in Swedish language proficiency if the course is taught in Swedish.

Literature

The literature list is not available through the web. Please contact the faculty.