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Syllabus:

Medicinal Chemistry: Design and Combinatorial Chemistry, 15 Credits

The course is discontinued from 2021-08-10

Swedish name: Läkemedelskemi: Design och kombinatorisk kemi (T)

This syllabus is valid: 2011-09-19 and until further notice

Course code: 5KE024

Credit points: 15

Education level: Second cycle

Main Field of Study and progress level: Chemistry: Second cycle, in-depth level of the course cannot be classified

Grading scale: TH teknisk betygsskala

Responsible department: Department of Chemistry

Revised by: Faculty Board of Science and Technology, 2021-08-10

Contents

The aim with the course is to give in-depth knowledge within the field of medicinal chemistry. The course focuses in particular on computational methods for design of compounds and parallel synthesis of compound libraries. The course cover the following topics; basic computational chemistry (quantum and molecular mechanics), molecular modelling, docking, QSAR, pharmacophore modelling, library design, parallel synthesis strategies, heterocycle chemistry, scavanger techniques. The course includes a mixture of theory and practice, where the theory is applied through hands-on exercises both in the computational and synthetic parts.

Required Knowledge

Chemometrics (5KE053, 7.5 hp), Medicinal Chemistry (5KE059/60, 15 hp) and Organic Chemistry (5KE067/68/113, 15 hp), or the equivalent.
Proficiency in English equivalent to Swedish upper secondary course English A (IELTS (Academic) with a minimum overall score of 5.5 and no individual score below 5.0. TOEFL PBT
(Paper-based Test) with a minimum total score of 530 and a minimum TWE score of 4. TOEFL iBT (Internet-based Test) with a minimum total score of 72 and a minimum score of 17 on the Writing Section).
Where the language of instruction is Swedish, applicants must prove proficiency in Swedish to the level required for basic eligibility for higher studies.

Literature

The literature list is not available through the web. Please contact the faculty.