Bioorganic Chemistry, 15 Credits

Contents

The course in bioorganic chemistry focuses on organic molecules, their properties and how those properties correlate to organic functional groups and three-dimensional structure. During the course, a large number of fundamental reactions are discussed from a mechanistic point of view, including their application to the synthesis of pharmaceutical drugs. A detailed understanding of reaction mechanisms is used to predict product outcome and to optimize product over bi-product formation. During two weeks of independent laboratory work, the skill of performing and analyzing organic experiments is practiced. The theory and application of modern spectroscopic methods, such as IR and NMR spectroscopy, is used to establish the structure of organic molecules.

Expected learning outcomes

After successfully finishing the course, the student shall:
- understand correlations between the structure of organic molecules and their properties/reactivity
- understand the three-dimensionality of organic molecules and the concept of chirality
- understand and use fundamental reaction mechanisms
- propose reactions/synthetic routes to simpler organic molecules
- propose reaction conditions favoring product over bi-product
- understand the application of organic molecules in some polymers, pharmaceutical drugs, etc
- plan, perform and analyze organic syntheses in the laboratory
- perform basic organic laboratory techniques
- keep a correct laboratory journal
- present the results of organic synthesis both in writing and orally
- determine the structure of organic molecules by IR and NMR spectroscopy.

Required Knowledge

Fundamentals of Chemistry (15 ECTS, 5KE080), or the equivlent. English proficiency equivalent to English A from Swedish Upper secondary education. (IELTS (Academic) with minimum score 5.5 and no individual score below 5.0. TOEFL (Paper based with minimum score 530 and minimum TWE 4). TOEFL (Internet based with minimum score 72 and minimum Written 17)). Basic entrance requirements for higher studies in Swedish language proficiency is also required if the course is taught in Swedish.

Form of instruction

The course is taught in lectures, classes, seminars and practical laboratory practicals. Seminars and laboratory practicals, including related lectures and seminars, are mandatory.

Examination modes

 Examinations are conducted by a written examination by the end of the course and by written and oral presentation of laboratory practicals. This can be combined with other examination forms. For the written exam is given one of the grades 5 Pass with distinction, 4 Pass with merit, 3 Pass, VG Pass with distinction, G Pass, U Fail. On the laboratory work is given one of the grades Fail (U), Pass (G). On the whole the course is given one of the grades 5 Pass with distinction, 4 Pass with merit, 3 Pass, VG Pass with distinction, G Pass, U Fail. To pass the course all examinations and compulsory modules must be approved. Those who pass the exam are not permitted a reexam for a higher grade. A student who has failed on two exams for a course or part of a course, are entitled to have appointed a new examiner, unless there are special reasons against it (HF 6 kap. § 22). Requests for new examiners are made to the Head of the Department of Chemistry.

Academic credit transfer is always evaluated individually (see the University rules for academic credit transfer).