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Syllabus:

Quantitative modelling of the building blocks of life, 7.5 Credits

The course is discontinued

Swedish name: Kvantitativ modellering av livets byggstenar

This syllabus is valid: 2015-12-14 and until further notice

Course code: 5BI192

Credit points: 7.5

Education level: Second cycle

Main Field of Study and progress level: Biology: Second cycle, has only first-cycle course/s as entry requirements

Grading scale: TH teknisk betygsskala

Responsible department: Department of Plant Physiology

Revised by: Faculty Board of Science and Technology, 2019-06-04

Contents

The technical development leads to a more precise measurement of cellular processes in time and space, which simultaneously provides an opportunity to more accurately design and test quantitative models of cellular processes. These models can be analysed analytically and numerically, and thereby create a better understanding of the different characteristics that a cell exhibits but also an opportunity to simulate and investigate the properties of the cell that it does not exhibit.
The course start with an overview of the cell's building blocks, their size and abundance. Then the study course continues with the study of spatial and temporal scales of various physical and chemical processes in the cell. How the cell's molecules, through a network of interactions, can process information about its environment and, based on this information control various cellular processes. The course provides a basis for quantitatively studying cellular processes using mathematical tools and computer simulations. The course content is close to current research and is based on an interdisciplinary integration of knowledge from physics, chemistry, biology, mathematics and computer science.

Expected learning outcomes

After completing the course, students should be able to:

  • Demonstrate the ability to analyse cellular processes by using analytical and numerical methods.
  • Quantify cellular length and time scales.
  • Quantify the cell's different macromolecules.
  • Quantify cellular information processing and control systems.
  • Briefly describe current research on the subject.
  • Present results orally and in writing.
  • Critically evaluate and analyse obtained results.

Required Knowledge

Eligibility requirements are 120 ECTS in science or engineering (Including Analysis 1 and 2, Linear Algebra and Differential equations), or equivalent.

Form of instruction

The course is taught in lectures, classes with problem solving and computer exercises, and group seminars.

Examination modes

Examinations are conducted by a written examination by the end of the course and by exercises during the course. To pass the course all examinations and compulsory projects must be approved. Students that have failed on the exam are entitled to two more occasions for re-exam. Those who pass the exam are not permitted a re-exam for a higher grade. A student who has failed on two exams for a course or part of a course, are entitled to have appointed a new examiner, unless there are special reasons against it (HF 6 kap. § 22). Requests for new examiners are made to the Head of the Department of Plant Physiology.

Literature

The literature list is not available through the web. Please contact the faculty.